Results 21 to 30 of about 19,093 (217)

Voriconazole as a secondary prophylaxis for cryptococcal meningitis during hematopoietic stem cell transplantation

IDCases, 2021
Antifungal prophylaxis is crucial for successful hematopoietic stem cell transplantation (HSCT). Maintenance therapy with fluconazole (FLCZ) is generally prescribed as secondary prophylaxis in patients with human immunodeficiency virus infection and non ...
Emiko Kashima, Keiki Nagaharu, Kazuko Ino, Yuka Sugimoto, Atsushi Fujieda, Keiki Kawakami, Isao Tawara   +6 more
doaj   +1 more source

Utility of clinical assessment, imaging, and cryptococcal antigen titer to predict AIDS-related complicated forms of cryptococcal meningitis

AIDS Research and Therapy, 2010
Background This study aimed to evaluate the prevalence and predictors of AIDS-related complicated cryptococcal meningitis. The outcome was complicated cryptococcal meningitis: prolonged (≥ 14 days) altered mental status, persistent (≥ 14 days) focal ...
Kandel Sean, Jafari Hamta, Sitapati Amy M, Caperna Joseph, Cachay Edward R, Mathews William C   +5 more
doaj   +1 more source

Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a large retrospective cohort of patients after solid organ transplantation [PDF]

, 2017
Background Cryptococcosis is the third most common invasive fungal infection in solid organ transplant (SOT) recipients. There are no nationally representative data describing the incidence, risk factors, and outcomes of cryptococcosis ...
George, Ige A, Olsen, Margaret A, Powderly, William G, Santos, Carlos A   +3 more
core   +2 more sources

“False negative” CSF cryptococcal antigen with clinical meningitis: Case reports and review of literature

Medical Mycology Case Reports, 2020
There is an increasing recognition of patients presenting with cryptococcal meningitis despite having a negative CSF cryptococcal antigen (CrAg). In this report, we describe three cases of patients with advanced immunosuppression who presented to ...
Morris K. Rutakingirwa, Tadeo K. Kiiza, Joshua Rhein   +2 more
doaj   +1 more source

Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease. [PDF]

, 2014
UnlabelledCryptococcus spp. cause life-threatening fungal infection of the central nervous system (CNS), predominantly in patients with a compromised immune system.
Bautos, Jennifer M, Gelli, Angie, Jamklang, Mantana, Na Pombejra, Sarisa, Tham, Rick, Thompson, George R, Uhrig, John P, Vu, Kiem   +7 more
core   +2 more sources

A case report of a brain herniation secondary to cryptococcal meningitis with elevated intracranial pressure in a patient with Human Immunodeficiency Virus/Acquired immunodeficiency syndrome (HIV/AIDS)

IDCases, 2022
Background: Cryptococcal meningitis is a major opportunistic infection in individuals with HIV. The worldwide annual incidence is estimated to be approximately one million cases per year, with the most significant burden in sub-Saharan Africa.
Nehemias Guevara, Abdulrasheed Akande, Mailing Flores Chang, Jane Atallah, Carol Epstein   +4 more
doaj   +1 more source

Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis. [PDF]

, 2018
BACKGROUND: Cryptococcal meningitis (CM) causes an estimated 180,000 deaths annually, predominantly in sub-Saharan Africa, where most patients receive fluconazole (FLC) monotherapy. While relapse after FLC monotherapy with resistant strains is frequently
Berman, J, Bicanic, T, Fisher, MC, Harrison, TS, Hope, W, Kivuyo, S, Kwon-Chung, J, Mfinanga, S, Molloy, SF, Needleman, L, Rhodes, J, Rugemalila, J, Segal, ES, Stone, NR   +13 more
core   +6 more sources

Cryptococcal antigenemia is associated with meningitis or death in HIV-infected adults with CD4 100–200 cells/mm3

BMC Infectious Diseases, 2020
Background Cryptococcal antigen (CrAg) screening with fluconazole prophylaxis has been shown to prevent cryptococcal meningitis and mortality for people living with HIV (PLWH) with CD4 
James Wykowski, Sean R. Galagan, Sabina Govere, Carole L. Wallis, Mahomed-Yunus Moosa, Connie Celum, Paul K. Drain   +6 more
doaj   +1 more source

Idiopathic CD4+ T-lymphocytopenia with cryptococcal meningitis: first case report from Cambodia. [PDF]

, 2009
We report on a patient with cryptococcal meningitis with CD4+ T-lymphocytopenia and no evidence of HIV ...
Augusto, E, Isaakidis, P, Kim, C, Mony, M, Raguenaud, M E   +4 more
core   +2 more sources

Another case of cryptococcal meningitis in a person without HIV who injects drugs: A possible risk factor in need of further investigation

Medical Mycology Case Reports, 2022
Cryptococcal meningitis is a fungal central nervous infection typically occurring in patients with severe immunocompromise. We present a case of cryptococcal meningitis occurring in a patient with active injection drug use (IDU) but no immunocompromising
L. Madeline McCrary, Ryan Paulus, J. Kyle Melvin, John Perfect, Becky L. White   +4 more
doaj   +1 more source