Impact of the BioFire FilmArray Meningitis-Encephalitis Panel on Management of Suspected Paediatric Central Nervous System Infections: A Single-Centre Retrospective Cohort Study. [PDF]
ABSTRACT Background Meningoencephalitis causes significant morbidity and mortality in children worldwide. Prompt diagnosis remains challenging, yet advances in molecular diagnostic technology have improved diagnostic performance. This study examined whether the introduction of the BioFire FilmArray meningitis/encephalitis (ME) multiplex panel impacted ...
Churcher LM +4 more
europepmc +2 more sources
Diagnostic Value of Inflammatory Biomarkers in Bacterial Meningitis: A Cross‐Sectional Study [PDF]
ABSTRACT Background Bacterial meningitis (BM) is a potentially life‐threatening condition that could rapidly progress to permanent brain damage, neurologic complications, or even death. Diagnostic tools to distinguish between BM and aseptic meningitis (AM) are essential to target the appropriate treatment to patients at great risk and concurrently ...
Koyiri V +8 more
europepmc +2 more sources
Real-World Evaluation of the BioFire FilmArray ME Panel: Diagnostic Accuracy and Clinical Utility. [PDF]
Central nervous system (CNS) infections carry high morbidity and mortality, yet traditional diagnostics often fail to identify the causative agent promptly. Rapid multiplex panels offer broader and faster pathogen detection, making it important to understand their real‐world clinical value.
Erinmez M +4 more
europepmc +2 more sources
Invasive Haemophilus influenzae Disease in Adults ≥65 Years, United States, 2011. [PDF]
BackgroundSince the introduction of the Haemophilus influenzae serotype b vaccine, H influenzae epidemiology has shifted. In the United States, the largest burden of disease is now in adults aged ≥65 years.
Bennett, Nancy +15 more
core +1 more source
Haemophilus influenzae infection in children is detected as sporadic cases and is characterized by polymorphism of clinical symptoms (rhinopharyngitis, purulent meningitis, acute epiglottitis, panniculitis, etc.), which complicates an early diagnosis and
Gennadii A. Kharchenko +1 more
doaj +1 more source
Introduction. Invasive Haemophilus influenza type b (Hib) infection often manifests as severe and complicated forms of purulent meningitis in children from birth to 6 years of age.
E. L. Sitkina +3 more
doaj +1 more source
Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens. [PDF]
The burden of meningitis in low-and-middle-income countries remains significant, but the infectious causes remain largely unknown, impeding institution of evidence-based treatment and prevention decisions.
Crawford, Emily D. +25 more
core +2 more sources
Haemophilus influenzae type b meningitis in a vaccinated and immunocompetent child
Invasive Haemophilus influenzae type b (Hib) disease decreased dramatically after the introduction of conjugate vaccine in routine immunization schedules.We report a case of a fifteen-months-old girl, previously healthy and vaccinated, admitted in the ...
Ana F. Almeida +3 more
doaj +1 more source
Haemophilus influenzae Meningitis in Adults [PDF]
Haemophilus influenzae meningitis though common in childhood is rarely seen in the adult. During the past four years eight cases of H. influenzae meningitis have been seen in St. Thomas's Hospital and four of these were in patients over 20 years old. There was a possible predisposing condition in two patients.
S J, Eykyn, R D, Thomas, I, Phillips
openaire +2 more sources
Conjugate Haemophilus influenzae type b vaccines for sickle cell disease. [PDF]
BACKGROUND: People affected with sickle cell disease are at high risk of infection from Haemophilus influenzae type b. Before the implementation of Haemophilus influenzae type b conjugate vaccination in high-income countries, this was responsible for a ...
Allali, Slimane +4 more
core +2 more sources

