Bacterial meningitis: Mechanisms of disease and therapy [PDF]
Bacterial meningitis continues to be a serious infectious disease with a high morbidity and mortality in young children. Early recognition and initiation of adequate treatment are the major determinants for a good outcome.
Groot, R. (Ronald) de +2 more
core +1 more source
Background: During the last two decades, significant changes have taken place in the epidemiology of meningitis, especially due to the global availability and expanding use of Hib vaccines.
Nihar Dash +4 more
doaj +1 more source
Diagnostic Performance of the QIAstat-Dx Meningitis/Encephalitis Panel: Insights From Seven Clinical Evaluations. [PDF]
This review compares the QIAstat‐Dx ME panel with the BioFire FilmArray ME panel across seven studies on CNS infections. The findings support the clinical utility of QIAstat‐Dx, highlighting its diagnostic performance, interpretative advantages, and the need for further real‐world evaluation in high‐risk populations.
Liotti FM +3 more
europepmc +2 more sources
From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]
In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core +3 more sources
Background. Meningitis is a serious communicable disease with high morbidity and mortality rates. It is an endemic disease in Egypt caused mainly by Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. In some settings, bacterial
Walaa Shawky Khater, Safia Hamed Elabd
doaj +1 more source
Risk factors for Haemophilus influenzae and pneumococcal respiratory tract colonization in CVID [PDF]
To the Editor: Disease-specific studies focused on infection risk in common variable immune deficiencies (CVIDs) are needed to define strategies for controlling respiratory infections predominantly due to bacteria such as Streptococcus pneumoniae and ...
Camilli, Romina +10 more
core +1 more source
Objetivo: analisar o perfil etiológico e alguns aspectos epidemiológicos das crianças com meningite bacteriana, internadas em um hospital público universitário.
Orlando C. Mantese +4 more
doaj +1 more source
Chorioamnionitis in the Second Trimester Secondary to Multidrug-Resistant <i>Haemophilus influenzae</i> Infection. [PDF]
Purpose Nontypeable Haemophilus influenzae (NTHi) is an emerging perinatal pathogen linked to chorioamnionitis, preterm birth, and early pregnancy loss. This case report describes the presentation, microbiologic findings, and management of second‐trimester NTHi‐associated chorioamnionitis, emphasizing diagnostic challenges and antimicrobial ...
Carlson KS, Korthals MB.
europepmc +2 more sources
Polymerase Chain Reaction Assay and Bacterial Meningitis Surveillance in Remote Areas, Niger
To compensate for the lack of laboratories in remote areas, the national reference laboratory for meningitis in Niger used polymerase chain reaction (PCR) to enhance the surveillance of meningitis caused by Neisseria meningitidis, Streptococcus ...
Fati Sidikou +7 more
doaj +1 more source
Vaccine-Induced Waning of Haemophilus influenzae Empyema and Meningitis, Angola
In Angola during 2003–2012, we detected Haemophilus influenzae in 18% of 2,634 and 26% of 2,996 bacteriologically positive pleural or cerebrospinal fluid samples, respectively, from children. After vaccination launch in 2006, H.
Heikki Peltola +8 more
doaj +1 more source

