Results 101 to 110 of about 20,003 (228)

Pneumococcal meningitis in children and adults before and after implementation of PCV13 into national pediatric immunization program: A cohort study in Taiwan

Journal of Infection and Public Health
Background: Streptococcus pneumoniae remains a leading cause of bacterial meningitis worldwide. Although pneumococcal conjugate vaccines (PCVs) have markedly reduced vaccine serotypes (VTs) invasive pneumococcal disease, the emergence of non-vaccine ...
Ching-Min Tang, Hsin-Chieh Li, Lin-Hui Su, Jainn-Jim Lin, Shao-Hsuan Hsia, Oi-Wa Chan, En-Pei Lee, Kuang-Lin Lin, Cheng-Hsun Chiu   +8 more
doaj   +1 more source

National, regional, and state-level burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in India: modelled estimates for 2000–15

The Lancet Global Health, 2019
Summary: Background: India accounts for a disproportionate burden of global childhood illnesses. To inform policies and measure progress towards achieving child health targets, we estimated the annual national and state-specific childhood mortality and ...
Brian Wahl, PhD, Apoorva Sharan, ScM, Maria Deloria Knoll, PhD, Rajesh Kumar, ProfMD, Li Liu, PhD, Yue Chu, MSPH, David A McAllister, MD, Harish Nair, ProfPhD, Harry Campbell, ProfMD, Igor Rudan, ProfMD, Usha Ram, ProfPhD, Molly Sauer, MPH, Anita Shet, MD, Robert Black, ProfMD, Mathuram Santosham, ProfMD, Katherine L O'Brien, ProfMD, Narendra K Arora, ProfMD   +16 more
doaj   +1 more source

Perceptions of measles, pneumonia, and meningitis vaccines among caregivers in Shanghai, China, and the health belief model: a cross-sectional study

BMC Pediatrics, 2017
Background In China, the measles vaccine is offered for free whereas the pneumococcal vaccine is a for-fee vaccine. This difference has the potential to influence how caregivers evaluate whether a vaccine is important or necessary for their child, but it
Abram L. Wagner, Matthew L. Boulton, Xiaodong Sun, Bhramar Mukherjee, Zhuoying Huang, Irene A. Harmsen, Jia Ren, Brian J. Zikmund-Fisher   +7 more
doaj   +1 more source

Phage lytic enzyme Cpl-1 for antibacterial therapy in experimental pneumococcal meningitis [PDF]

, 2008
Treatment of bacterial meningitis caused by Streptococcus pneumoniae is increasingly difficult, because of emerging resistance to antibiotics. Recombinant Cpl-1, a phage lysin specific for S.
Grandgirard, Denis, Vincent A. Fischetti, Fischetti, Vincent A., Loeffler, Jutta M., Jutta M. Loeffler, Stephen L. Leib, Leib, Stephen L., Denis Grandgirard   +7 more
core   +1 more source

Progranulin Plays a Protective Role in Pneumococcal Meningitis by Inhibiting Pyroptosis

Immunity, Inflammation and Disease
Objective Pneumococcal meningitis is a serious infectious disease with a high mortality rate and a global presence, and survivors have different degrees of neurological sequelae as a consequence of the host response to the infection.
Jingyao Wang, Lihua Kang, Wenlong Xu, Jiangming Xiao, Yajun Min, Sijie Li, Changlong Zhou, Yibing Yin, Xuemei Zhang, Qun Zhang   +9 more
doaj   +1 more source

PNEUMOCOCCAL MENINGITIS [PDF]

BMJ, 1917
C, Worster-Drought, A M, Kennedy
openaire   +2 more sources

Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis. [PDF]

, 2019
BACKGROUND Pneumococcal meningitis is associated with high risk of neurological sequelae such as cognitive impairment and hearing loss. These sequelae are due to parenchymal brain and inner ear damage primarily induced by the excessive inflammatory ...
Grandgirard, Denis, Le, Ngoc Dung, Zemp, Jonas, Leib, Stephen L., Muri, Lukas Kilian   +4 more
core   +1 more source

Effects of clinically used antioxidants in experimental pneumococcal meningitis [PDF]

, 2000
Reactive oxygen intermediates mediate brain injury in bacterial meningitis. Several antioxidant drugs are clinically available, including N-acetylcysteine (NAC), deferoxamine (DFO), and trylizad-mesylate (TLM).
Pfister, Luz-Andrea, Leppert, David, Täuber, Martin G., Leib, Stephen L., Auer, Marc   +4 more
core   +1 more source

The impact of childhood pneumococcal vaccination on hospital admissions in England: a whole population observational study

BMC Infectious Diseases, 2019
Background Pneumococcal infections are major causes of morbidity and mortality worldwide. We use routine hospital admissions data and time-series modelling analysis to estimate the impact of the seven and thirteen valent pneumococcal conjugate vaccines ...
Tinevimbo Shiri, Noel D. McCarthy, Stavros Petrou   +2 more
doaj   +1 more source

Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

EBioMedicine, 2016
Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections.
Lene F. Lundbo, Zitta Barrella Harboe, Louise N. Clausen, Mads V. Hollegaard, Henrik T. Sørensen, David M. Hougaard, Helle B. Konradsen, Mette Nørgaard, Thomas Benfield   +8 more
doaj   +1 more source