Results 81 to 90 of about 20,003 (228)

Assessing the Impact of TLR4 rs4986790 Polymorphism on Bacterial Meningitis Risk: A Systematic Review and Meta-Analysis

Annals of Indian Academy of Neurology
Background and Objectives: Toll-like receptor (TLR2) gene plays an important role in the pathogenesis of bacterial meningitis (such as meningococcal meningitis and pneumococcal meningitis).
Praveen Kumar Chandra Sekar, Ramakrishnan Veerabathiran   +1 more
doaj   +1 more source

Targeting the Dynamic Susceptibility Window: Time‐Sensitive Photodynamic Synergy With Antibiotics Against Streptococcus spp

Lasers in Surgery and Medicine, Volume 58, Issue 4, Page 331-342, April 2026.
ABSTRACT Objective Evaluated the antimicrobial efficacy of curcumin‐mediated photodynamic inactivation (PDI) against both sensitive and resistant strains of Streptococcus pneumoniae and Streptococcus pyogenes, as well as its potential to enhance antibiotic effects (amoxicillin, ceftriaxone, erythromycin).
Isabella S. Gonçalves, Jennifer M. Soares, Vanderlei S. Bagnato, Kate C. Blanco   +3 more
wiley   +1 more source

Pneumococcal meningitis in the newborn period in a prevaccination era: a 10-year experience at a tertiary intensive care unit

The Turkish Journal of Pediatrics, 2011
There are few data with respect to pneumococcal meningitis in neonates. Epidemiological aspects, clinical features and outcomes in newborn infants diagnosed with pneumococcal meningitis were evaluated in this study.
Ahmet Yağmur Baş, Nihal Demirel, Mustafa Aydin, Ayşegül Zenciroglu, Alparslan Tonbul, Gönül Tanir   +5 more
doaj  

Epidemiology of pneumococcal meningitis in sentinel hospital surveillance of Viet Nam, 2015–2018

BMC Infectious Diseases
Background Streptococcus pneumoniae (S. pneumoniae), Haemophilus influenzae (H. influenzae), and Neisseria meningitidis (N. meningitidis) are leading causes of childhood bacterial meningitis and preventable by vaccines.
Dac Trung Nguyen, Thi Loan Nguyen, Allison Olmsted, Thi Hong Duong, Hong Mai Hoang, Lien Huong Nguyen, Mahamoudou Ouattara, Jennifer Milucky, Fernanda C. Lessa, Thi Trang Dai Vo, Van Thanh Phan, Thi Hien Anh Nguyen, Nguyen My Nguyet Pham, Huu Khanh Truong, Thi Quynh Tram Phan, Thi Hong Hoa Bui, Van Khang Pham, Makiko Iijima, Binh Le, Lindsay Kim, Jennifer Loo Farrar   +20 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, Volume 600, Issue 6, Page 864-893, March 2026.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Pathophysiology of pneumococcal meningitis [PDF]

, 2016
Bacterial meningitis is a serious infectious disease, involving the membranes surrounding the brain and spinal cord, and the subarachnoid space. In the Netherlands most common causative agents are Streptococcus pneumoniae (72%) and Neisseria meningitidis
Geldhoff, M.
core   +1 more source

How Far Can we Go? Managing Moyamoya Syndrome in a 3‐Year‐Old With Thalassemia Major: A Rare Pediatric Case From Nepal

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Moyamoya syndrome (MMS) is a rare progressive cerebrovascular disorder causing stenosis of intracranial arteries and collateral vessel formation. Pediatric presentations often include ischemic strokes, and coexisting Thalassemia Major may worsen vascular outcomes.
Kshitiz Parajuli, Abhisek Jha, Aron Neupane, Shristi Gupta, Nischal Timsina, Sagar Bhagat, Raja Babu Gupta, Anand Sah, Anup Katwal   +8 more
wiley   +1 more source

Pneumococcal meningitis induces apoptosis in recently postmitotic immature neurons in the dentate gyrus of neonatal rats [PDF]

, 2007
Bacterial meningitis is associated with high rates of morbidity and mortality, despite advances in antibiotic therapy. Meningitis caused by Streptococcus pneumoniae is associated with a particularly high incidence of neurological sequelae including ...
Grandgirard, D, Tauber, Martin G., Pleasure, S J, Leib, Stephen L., Kummer, J, Bifrare, Y-D   +5 more
core   +1 more source

Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage.

PLoS Pathogens, 2013
Streptococcus pneumoniae (pneumococcal) meningitis is a common bacterial infection of the brain. The cholesterol-dependent cytolysin pneumolysin represents a key factor, determining the neuropathogenic potential of the pneumococci.
Carolin Wippel, Jana Maurer, Christina Förtsch, Sabrina Hupp, Alexandra Bohl, Jiangtao Ma, Timothy J Mitchell, Stephanie Bunkowski, Wolfgang Brück, Roland Nau, Asparouh I Iliev   +10 more
doaj   +1 more source

The Current Landscape and Future Prospects of Vaccine Manufacturing in Africa: Challenges, Innovations, and Opportunities: A Narrative Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Africa has significant challenges in meeting its vaccination needs, including inadequate manufacturing capacity, infrastructure deficiencies, a scarcity of experienced personnel, regulatory hurdles, restricted access to technology and intellectual property.
Courage Chandipwisa, Agness Shimilimo, Olivier Uwishema, Helen Onyeaka   +3 more
wiley   +1 more source