Results 71 to 80 of about 91,384 (218)

Epidemiology of pneumococcal meningitis in sentinel hospital surveillance of Viet Nam, 2015–2018

BMC Infectious Diseases
Background Streptococcus pneumoniae (S. pneumoniae), Haemophilus influenzae (H. influenzae), and Neisseria meningitidis (N. meningitidis) are leading causes of childhood bacterial meningitis and preventable by vaccines.
Dac Trung Nguyen, Thi Loan Nguyen, Allison Olmsted, Thi Hong Duong, Hong Mai Hoang, Lien Huong Nguyen, Mahamoudou Ouattara, Jennifer Milucky, Fernanda C. Lessa, Thi Trang Dai Vo, Van Thanh Phan, Thi Hien Anh Nguyen, Nguyen My Nguyet Pham, Huu Khanh Truong, Thi Quynh Tram Phan, Thi Hong Hoa Bui, Van Khang Pham, Makiko Iijima, Binh Le, Lindsay Kim, Jennifer Loo Farrar   +20 more
doaj   +1 more source

Subtotal Versus Total Splenectomy in Children With Sickle Cell Disease: Clinical Outcomes and Splenic Function Assessed by Pocked Red Blood Cell Count

American Journal of Hematology, Volume 101, Issue 10, Page 2654-2658, October 2026.
Alma Al Sibaaie, Abdoulaye Sissoko, Carmen Capito, Christophe Chardot, Mariane de Montalembert, Valentine Brousse, Joséphine Brice, Martina Bevacqua, Camille Roussel, Lucie Dumas, Astan Cissé, Pierre Buffet, Slimane Allali   +12 more
wiley   +1 more source

Parental Socio‐Economic Factors and the Risk of Invasive Bacterial Infections in Children: A Register‐Based Finnish Study

Acta Paediatrica, Volume 115, Issue 7, Page 1487-1495, July 2026.
ABSTRACT Aim Little is known about how socio‐economic factors influence severe childhood bacterial infections. We explored whether parental socio‐economic status correlates with the risk of invasive bacterial infections in the offspring. Methods Data on children < 16 years with community‐acquired blood or cerebrospinal fluid culture–positive bacterial ...
Kyrönlahti Anniina, Hermunen Teemu, Nieminen Tea, Koivisto Karoliina, Rantanen Matti, Saxén Harri, Madanat‐Harjuoja Laura   +6 more
wiley   +1 more source

New therapies for pneumococcal meningitis

, 2004
The treatment of pneumococcal meningitis remains a major challenge, as reflected by the continued high morbidity and case fatality of the disease. The worldwide increase of penicillin-resistant pneumococci and more recently cephalosporin- and vancomycin ...
Täuber, MG, Cottagnoud, PH
core   +1 more source

Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage.

PLoS Pathogens, 2013
Streptococcus pneumoniae (pneumococcal) meningitis is a common bacterial infection of the brain. The cholesterol-dependent cytolysin pneumolysin represents a key factor, determining the neuropathogenic potential of the pneumococci.
Carolin Wippel, Jana Maurer, Christina Förtsch, Sabrina Hupp, Alexandra Bohl, Jiangtao Ma, Timothy J Mitchell, Stephanie Bunkowski, Wolfgang Brück, Roland Nau, Asparouh I Iliev   +10 more
doaj   +1 more source

Dynamic models of pneumococcal carriage and the impact of the Heptavalent Pneumococcal Conjugate Vaccine on invasive pneumococcal disease. [PDF]

, 2010
BACKGROUND: The 7-valent pneumococcal conjugate vaccine has been introduced in national immunisation programmes of most industrialised countries and recently in two African GAVI eligible countries (Rwanda and The Gambia). However the long term effects of
George, Robert, Robert George, Y.H. Choi, Miller, Elizabeth, Edmunds, John W., Elizabeth Miller, Melegaro, Alessia, Yoon Hong Choi, E. Miller, Choi, Yoon Hong, Gay, Nigel J, Edmunds, W John, Nigel J Gay, R. George, W John Edmunds, Alessia Melegaro, N.J. Gay, W.J. Edmunds, Gay, Nigel J., George Robert, Miller Elizabeth, Edmunds W John, Choi Yoon, Gay Nigel J, Melegaro Alessia   +24 more
core   +2 more sources

Development of a Clinical Severity Score for Indian Sickle Cell Anaemia Patients

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background Sickle cell anaemia (SCA) is a monogenic disorder but shows variable disease severity. We evaluated the utility of paediatric severity scores (PSS) in Indian patients and developed two modified scores: Indian Severity Score 1 (ISS1) by adding four clinical parameters to PSS, and ISS2 by excluding four biochemical measures from ISS1.
Suraj S. Nongmaithem, Amitabh Biswas, Swaroop Iyer, Jandhayala Vyshnavi, Archana Wath, Giriraj R. Chandak, Dipty Jain   +6 more
wiley   +1 more source

Epidemiologic, clinical and bacteriologic characteristics of pneumococcal meningitis in pediatric patients from Lima, Peru

Revista Peruana de Medicina Experimental y Salud Pública, 2016
Objectives. To describe the clinical characteristics, lethality, antibiotic susceptibility, and serotype distribution of pneumococcal meningitis in pediatric patients in Lima, Peru. Materials and Methods.
Long Davalos, Yessica Terrazas, Ana Quintana, Martha Egoavil, Katherine Sedano, María E. Castillo, Isabel Reyes, Eduardo Chaparro, Wilda Silva, Francisco Campos, Andrés Saenz, Roger Hernandez, Olguita del Águila, Daniel Guillén Pinto, Theresa J. Ochoa   +14 more
doaj   +1 more source

A novel case of autosomal recessive CARD11 loss‐of‐function underlying impaired antiviral immunity and a review of literature

Clinical &Translational Immunology, Volume 15, Issue 5, 2026.
We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson, Cecilia Verryt, Paula Keating, Thomas Saunders, Samuel Dalton, Barry D Hock, Liping Goddard, Kylie Drake, Anja Werno, John O'Donnell, Jeffrey R Stinson, Andrew L Snow, Kuang‐Chih Hsiao   +12 more
wiley   +1 more source

Brain levels of neuropeptide Y in experimental pneumococcal meningitis [PDF]

, 1993
Neuropeptide Y (NPY), which is found in high concentrations in several regions of the brain including nuclei of the brain stem and in nerve fibers surrounding cerebral vessels, has been proposed to play a role in regulating cerebral blood flow (CBF) and ...
Täuber, MG, Kennedy, SL, Guerra-Romero, L, Ferriero, D, Sheldon, RA   +4 more
core   +2 more sources