Results 51 to 60 of about 91,384 (218)

Toxicity in neuronal cells caused by cerebrospinal fluid from pneumococcal and gram-negative meningitis [PDF]

, 1992
To identify neurotoxic factors in meningitis, a neuronal cell line (HN33.1) was exposed to cerebrospinal fluid (CSF) obtained from rabbits with pneumococcal meningitis or Escherichia coli meningitis or 2 h and 6 h after meningitis was induced by ...
M. G. Tauber, H. Loetscher, Täuber, MG, Sachdeva, M, Lesslauer, W, Kennedy, SL, S. L. Kennedy, W. Lesslauer, M. Sachdeva, Loetscher, H   +9 more
core   +1 more source

Retrospective database analysis for clinical diagnoses commonly associated with pneumococcal diseases in the Malaysian healthcare system over a 3-year period (2013–2015)

BMC Infectious Diseases
Background Pneumococcal disease caused by Streptococcus pneumoniae is an important cause of morbidity and mortality across all ages, particularly in younger children and older adults. Here, we describe pneumococcal disease hospitalizations at Ministry of
Saravanan S. R. Sundaramurthy, Kristen E. Allen, Mark A. Fletcher, Kok Fui Liew, Boekhtiar Borhanuddin, Mohammad Ali, Graciela Morales, Bradford Gessner, Jerusha Naidoo, Jo Southern   +9 more
doaj   +1 more source

Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome

EBioMedicine, 2016
Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Early recognition of the pathogen and subsequent innate immune response play a vital role in disease susceptibility and outcome. Genetic variations in innate immune genes
Bart Ferwerda, Mercedes Valls Serón, Aldo Jongejan, Aeilko H. Zwinderman, Madelijn Geldhoff, Arie van der Ende, Frank Baas, Matthijs C. Brouwer, Diederik van de Beek   +8 more
doaj   +1 more source

Greater Cochlear Damage in Otogenic Versus Meningogenic Meningitis: Hearing Rehabilitation Implications

The Laryngoscope, Volume 136, Issue 9, Page 3998-4005, September 2026.
Otogenic route of meningitis was associated with greater cochlear hair cell loss in comparison with the meningogenic one in this otopathology study. Neuronal depletion has been traditionally implicated in failed hearing rehabilitation of post‐meningitis deafness.
Matheus Pedrosa Tavares, Henrique Furlan Pauna, Rafael da Costa Monsanto, Nevra Keskin‐Yilmaz, Breno Lima de Almeida, Norma de Oliveira Penido   +5 more
wiley   +1 more source

A Prospective Longitudinal Study of the Clinical Outcomes from Cryptococcal Meningitis following Treatment Induction with 800 mg Oral Fluconazole in Blantyre, Malawi [PDF]

, 2013
Introduction: Cryptococcal meningitis is the most common neurological infection in HIV infected patients in Sub Saharan Africa, where gold standard treatment with intravenous amphotericin B and 5 flucytosine is often unavailable or difficult to ...
Mavuto Mukaka, Rothe, Camilla, Feasey, NA, Tom Harrison, van Oosterhout Joep J., Denis, Brigitte, Lalloo David G., Goodson, P, Rothe, C, Jean Chikafa, Sloan, DJ, Goodson, Patrick, Nicholas A Feasey, Mukaka, Mavuto, Joep J van Oosterhout, Lalloo, DG, Allain, T, Heyderman Robert S., Camilla Rothe, Harrison, T, Sloan Derek J., Harrison, Tom, Harrison Tom, Sloan, Derek J., Allain Theresa, Mukaka, M, Lalloo, David G., Theresa Allain, Goodson Patrick, Denis, B, van Oosterhout, JJ, Chikafa, Jean, Derek J Sloan, David G Lalloo, Chikafa, J, Patrick Goodson, Brigitte Denis, Rothe Camilla, Robert S Heyderman, Feasey Nicholas A., Chikafa Jean, van Oosterhout, Joep J., Mukaka Mavuto, Allain, Theresa, Feasey, Nick; id_orcid, Heyderman, RS, Feasey, Nicholas A., Denis Brigitte, Lalloo, David; id_orcid, Heyderman, Robert S.   +49 more
core   +1 more source

How Do Climatic Factors Directly Influence the Incidence and Risk of Meningococcal Meningitis Across the African Meningitis Belt? A Narrative Literature Review

GeoHealth, Volume 10, Issue 9, September 2026.
Abstract Globally, the highest incidence of meningococcal meningitis occurs within the African meningitis belt, spanning 26 countries across sub‐Saharan Africa. Meningococcal meningitis incidence is highly seasonal in this region specifically, with outbreaks mostly occurring during the dry season, characterized by low rainfall and atmospheric humidity,
Molly Cliff, Kanny Diallo, Richard B. Yapi, Axelle B. D. Tano, Sally Jahn, Caroline M. Wainwright, Caroline Trotter   +6 more
wiley   +1 more source

A Trial of a 7-Valent Pneumococcal Conjugate Vaccine in HIV-Infected Adults. [PDF]

, 2010
BACKGROUND: Streptococcus pneumoniae is a leading and serious coinfection in adults with human immunodeficiency virus (HIV) infection, particularly in Africa.
Zijlstra, EE, Molyneux, Malcolm E, White, Sarah A., Mwaiponya, Martin, Mwalukomo, Thandie, Gordon, Stephen, Zijlstra, Eduard E, Longwe, Herbert, French, N, Mwalukomo, T, White, SA, French, Neil, Gordon, SB, Mwaiponya, M, Gilks, CF, Gilks, Charles F, Mwafulirwa, Gershom, Molyneux, Malcolm E., Mwafulirwa, G, Molyneux, ME, Gordon, Stephen B., Gordon, Stephen B, White, Sarah; id_orcid, Longwe, H, Gilks, Charles F., White, Sarah A, Zijlstra, Eduard E.   +26 more
core   +1 more source

Burden of Pneumococcal Disease in Northern Togo before the Introduction of Pneumococcal Conjugate Vaccine.

PLoS ONE, 2017
BackgroundS. pneumoniae is a leading cause of meningitis morbidity and mortality in the African meningitis belt, but little is known of its contribution to the burden of pneumonia in the region.
Jennifer C Moïsi, Makawa-Sy Makawa, Haoua Tall, Kodjo Agbenoko, Berthe-Marie Njanpop-Lafourcade, Stanislas Tamekloe, Moussa Amidou, Judith E Mueller, Bradford D Gessner   +8 more
doaj   +1 more source

Streptococcus pneumoniae serotype-2 childhood meningitis in Bangladesh: a newly recognized pneumococcal infection threat. [PDF]

PLoS ONE, 2012
BACKGROUND: Streptococcus pneumoniae is a leading cause of meningitis in countries where pneumococcal conjugate vaccines (PCV) targeting commonly occurring serotypes are not routinely used.
Samir K Saha, Hassan M Al Emran, Belal Hossain, Gary L Darmstadt, Senjuti Saha, Maksuda Islam, Atique I Chowdhury, Dona Foster, Aliya Naheed, Shams El Arifeen, Abdullah H Baqui, Shamim A Qazi, Stephen P Luby, Robert F Breiman, Mathuram Santosham, Robert E Black, Derrick W Crook, Pneumococcal Study Group   +17 more
doaj   +1 more source

Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom, Abdul‐Halim Osman, Onyansaniba K. Ntim, Fleischer C. N. Kotey, Eric S. Donkor   +4 more
wiley   +1 more source