Results 31 to 40 of about 20,003 (228)

The Pathophysiology of Pneumococcal Meningitis

open access: yesAnnals of Medicine, 1994
The interactions between pneumococcal surface components and host defence systems that initiate pneumococcal meningitis have been studied in considerable molecular detail over the past decade. In this sense, the pneumococcus has served as a prototype for the unravelling of the genesis of inflammation caused by gram-positive bacteria.
B, Spellerberg, E I, Tuomanen
openaire   +2 more sources

Genome analysis of a highly virulent serotype 1 strain of streptococcus pneumoniae from West Africa [PDF]

open access: yes, 2012
Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and bacteremia, estimated to cause 2 million deaths annually. The majority of pneumococcal mortality occurs in developing countries, with serotype 1 a leading cause in these areas.
Loman Nicholas J.   +43 more
core   +1 more source

Trends in incidence of pneumococcal disease before introduction of conjugate vaccine: South West England, 1996-2005. [PDF]

open access: yes, 2008
Introduction of pneumococcal conjugate and polysaccharide vaccines into the United Kingdom's routine immunization programmes is expected to change the epidemiology of invasive pneumococcal disease (IPD).
Dance, DA   +21 more
core   +1 more source

Clinical outcome of pneumococcal meningitis during the emergence of pencillin-resistant Streptococcus pneumoniae: an observational study

open access: yesBMC Infectious Diseases, 2011
Background Prior to the availability of generic third-generation cephalosporins, penicillins were widely used for treatment of pneumococcal meningitis in developing countries despite concerns about rising levels of penicillin resistance among ...
Gouveia Edilane L   +11 more
doaj   +1 more source

Adult meningitis in a setting of high HIV and TB prevalence: findings from 4961 suspected cases. [PDF]

open access: yes, 2010
BACKGROUND: The presentation and causes of adult meningitis in South Africa have changed substantially as a result of HIV. Knowledge of aetiology and laboratory findings in patients presenting with meningitis are important in guiding management.
Crede Tom   +25 more
core   +1 more source

Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]

open access: yes, 2011
We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Mitchell, Tim J   +52 more
core   +1 more source

Pneumococcal meningitis in adults in 2014–2018 after introduction of pediatric 13-valent pneumococcal conjugate vaccine in Japan

open access: yesScientific Reports, 2022
We assessed the impact of the pediatric 13-valent pneumococcal conjugate vaccine (PCV13) on pneumococcal meningitis in adults in Japan in 2014–2018 by comparing epidemiological characteristics of adults with invasive pneumococcal disease with (n = 222 ...
Bin Chang   +21 more
doaj   +1 more source

Ten years of surveillance for invasive Streptococcus pneumoniae during the era of antiretroviral scale-up and cotrimoxazole prophylaxis in Malawi. [PDF]

open access: yes, 2011
OBJECTIVE: To document trends in invasive pneumococcal disease (IPD) in a central hospital in Malawi during the period of national scale-up of antiretroviral therapy (ART) and cotrimoxazole prophylaxis.
Mavuto Mukaka   +41 more
core   +1 more source

Monitoring the introduction of pneumococcal conjugate vaccines into West Africa: design and implementation of a population-based surveillance system. [PDF]

open access: yes, 2012
Routine use of pneumococcal conjugate vaccines (PCVs) in developing countries is expected to lead to a significant reduction in childhood deaths. However, PCVs have been associated with replacement disease with non-vaccine serotypes.
Greenwood, Brian M   +55 more
core   +1 more source

Serotype Distribution and Antimicrobial Susceptibility Pattern of Streptococcus pneumoniae in COVID-19 Pandemic Era in Brazil

open access: yesMicroorganisms
Despite the introduction of the pneumococcal vaccine, Streptococcus pneumoniae remains a cause of invasive diseases in Brazil. This study provides the distribution of serotypes and antimicrobial susceptibility patterns for pneumococcal isolates before ...
Samanta C. G. Almeida   +4 more
doaj   +1 more source

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