Results 11 to 20 of about 91,384 (218)

Serotype Distribution of Remaining Pneumococcal Meningitis in the Mature PCV10/13 Period: Findings from the PSERENADE Project [PDF]

Microorganisms, 2021
Pneumococcal conjugate vaccine (PCV) introduction has reduced pneumococcal meningitis incidence. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project described the serotype distribution of remaining pneumococcal ...
Maria Garcia Quesada, Yangyupei Yang, Julia C. Bennett, Kyla Hayford, Scott L. Zeger, Daniel R. Feikin, Meagan E. Peterson, Adam L. Cohen, Samanta C. G. Almeida, Krow Ampofo, Michelle Ang, Naor Bar-Zeev, Michael G. Bruce, Romina Camilli, Grettel Chanto Chacón, Pilar Ciruela, Cheryl Cohen, Mary Corcoran, Ron Dagan, Philippe De Wals, Stefanie Desmet, Idrissa Diawara, Ryan Gierke, Marcela Guevara, Laura L. Hammitt, Markus Hilty, Pak-Leung Ho, Sanjay Jayasinghe, Jackie Kleynhans, Karl G. Kristinsson, Shamez N. Ladhani, Allison McGeer, Jason M. Mwenda, J. Pekka Nuorti, Kazunori Oishi, Leah J. Ricketson, Juan Carlos Sanz, Larisa Savrasova, Lena Petrova Setchanova, Andrew Smith, Palle Valentiner-Branth, Maria Teresa Valenzuela, Mark van der Linden, Nina M. van Sorge, Emmanuelle Varon, Brita A. Winje, Inci Yildirim, Jonathan Zintgraff, Maria Deloria Knoll, the PSERENADE Team   +49 more
doaj   +3 more sources

Estudi experimental del tractament de la meningitis pneumocòcica produïda per soques resistents a cefalosporines de tercera generació. Virulència, eficàcia i resposta inflamatòria [PDF]

, 2006
[cat] La meningitis pneumocòcica és una malaltia associada a una elevada mortalitat (20-40) i a l'aparició de seqüeles neurològiques en un 30% dels pacients, nens i adults, que sobreviuen.
Ribes Miravet, Sandra
core   +6 more sources

Bioengineered Extracellular Vesicles Mitigate Neuroinflammation by Neutralizing Pneumolysin and Delaying Disease Onset in Experimental Pneumococcal Meningitis. [PDF]

J Extracell Vesicles
ABSTRACT Bacterial meningitis is a life‐threatening neurological disorder frequently caused by a Streptococcus pneumoniae (the pneumococcus) infection of the brain. Standard treatment consists of antibiotics to eliminate bacteria and dexamethasone to reduce inflammation.
Farmen K, Mamand DR, Tofiño-Vian M, Yfanti G, Liang X, Zhou H, Hou VWQ, Andaloussi SE, Wiklander OPB, Iovino F.   +9 more
europepmc   +2 more sources

The Burden of Streptococcus Pneumoniae-Related Admissions in Pediatric Population: A Retrospective Cohort Study Between Years 2018-2023 From a Southern Italian Region. [PDF]

Health Sci Rep
ABSTRACT Background Pneumococcus are often found in the respiratory tract of healthy people, especially children, and are a common cause of infections such as otitis media, sinusitis, conjunctivitis and community‐acquired pneumonia. In other cases, the bacteria can cause more serious conditions known collectively as invasive pneumococcal disease (IPD),
Di Giovanni P, Di Martino G, Petrangelo M, Donatiello V, Vaccaro F, Tognaccini L, Trebbi E, Aita T, Romano F, Staniscia T.   +9 more
europepmc   +2 more sources

Meningococcal and pneumococcal meningitis in Northern Ghana [PDF]

, 2008
Despite improvements in technology, treatments and understanding of how bacterial meningitis develops, the disease remains a potentially life-threatening emergency capable of causing significant morbidity and mortality. N. meningitidis, S.
Forgor, Abdulai Adams
core   +1 more source

Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis. [PDF]

, 2009
During acute bacterial infections such as meningitis, neutrophils enter the tissue where they combat the infection before they undergo apoptosis and are taken up by macrophages.
Häcker Georg, Bianca Obermaier, Georg Häcker, Robert Paul, Hans Häcker, Obermaier, Bianca, Paul Robert, Frankenberg, Tobias, Koedel, Uwe, Uwe Koedel, Frankenberg Tobias, Paul, Robert, Susanne Kirschnek, Kirschnek, Susanne, Tobias Frankenberg, Kirschnek Susanne, Obermaier Bianca, Koedel Uwe, Häcker, Hans, Häcker, Georg, Häcker Hans   +20 more
core   +2 more sources

Leukocyte attraction by CCL20 and its receptor CCR6 in humans and mice with pneumococcal meningitis.

PLoS ONE, 2014
We previously identified CCL20 as an early chemokine in the cerebrospinal fluid (CSF) of patients with pneumococcal meningitis but its functional relevance was unknown.
Matthias Klein, Matthijs C Brouwer, Barbara Angele, Madelijn Geldhoff, Gabriel Marquez, Rosa Varona, Georg Häcker, Helga Schmetzer, Hans Häcker, Sven Hammerschmidt, Arie van der Ende, Hans-Walter Pfister, Diederik van de Beek, Uwe Koedel   +13 more
doaj   +1 more source

Clinical and Bacteriological Analysis of Pediatric Pneumococcal Meningitis after 13-Valent Pneumococcal Conjugate Vaccine Introduction in Japan

Microbiology Spectrum, 2022
Streptococcus pneumoniae is one of the leading causes of meningitis in children. In Japan, since the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13), the number of pneumococcal meningitis due to non-PCV13 serotypes in children has ...
Erika Kurihara, Kenichi Takeshita, Saori Tanaka, Noriko Takeuchi, Misako Ohkusu, Haruka Hishiki, Naruhiko Ishiwada   +6 more
doaj   +1 more source

The Pathophysiology of Pneumococcal Meningitis

Annals of Medicine, 1994
The interactions between pneumococcal surface components and host defence systems that initiate pneumococcal meningitis have been studied in considerable molecular detail over the past decade. In this sense, the pneumococcus has served as a prototype for the unravelling of the genesis of inflammation caused by gram-positive bacteria.
B, Spellerberg, E I, Tuomanen
openaire   +2 more sources

Bacteremia causes hippocampal apoptosis in experimental pneumococcal meningitis

BMC Infectious Diseases, 2010
Background Bacteremia and systemic complications both play important roles in brain pathophysiological alterations and the outcome of pneumococcal meningitis.
Rowland Ian, Leib Stephen L, Østergaard Christian, Brandt Christian T   +3 more
doaj   +1 more source