Results 41 to 50 of about 494,505 (356)

Prolonged shedding of SARS-CoV-2 at high viral load amongst hospitalised immunocompromised persons living with HIV in South Africa

International Journal of Infectious Diseases, 2022
Purpose: There is limited information on SARS-CoV-2 shedding duration amongst persons living with HIV (PLWH). We hypothesised that PLWH shed SARS-CoV-2 for longer periods and at higher viral load than HIV-uninfected persons. Methods & Materials: From
S. Meiring, S. Tempia, J. Bhiman, J. Kleynhans, A. Buys, M. Makhasi, M. Mcmorrow, J. Moyes, V. Quan, S. Walaza, M. Du Plessis, N. Wolter, A. Von Gottberg, C. Cohen   +13 more
doaj   +1 more source

Febre purpúrica brasileira: resultados preliminares da investigação etiológica

Revista do Instituto de Medicina Tropical de São Paulo, 1987
Em várias regiões do interior do Estado de São Paulo, notificou-se a partir do final de 1984 a 1986, a ocorrência de doença até então desconhecida, com características clínicas, em muitos aspectos, semelhante à meningococcemia.
K. Irino, I. M. L. Lee, M. Kaku, M. C. C. Brandileone, C. E. A. Melles, C. E. Levy, S. E. Berkley, D. W. Fleming, G. A. Silva, L. Harrison   +9 more
doaj   +1 more source

Pneumococcal Serotype Identification by Capsular Sequence Typing (CST): A Modified Novel Approach for Serotyping Directly in Clinical Samples

Diagnostics, 2021
As almost 60–70% of Invasive Pneumococcal Disease (IPD) is identified by nonculture methods in Greece, serotyping is of high importance for the better monitoring of pneumococcal serotypes due to the availability of conjugate vaccines.
Nektarios Marmaras, Athanasia Xirogianni, Anastasia Papandreou, Efthymia Petinaki, Vana Papaevangelou, Maria Tsolia, Georgina Tzanakaki   +6 more
doaj   +1 more source

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance. [PDF]

, 2019
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
Aller, Altamirano, Arechavala, Bicanic, Bicanic, Boeva, Chang, Chen, Dannaoui, DePristo, Drusano, Harrison, Li, Longley, Loyse, Martin, Mayanja-Kizza, McKenna, Molloy, Mondon, Neely, Nixon, Nussbaum, Saag, Sionov, Sionov, Stone, Stott, Stott, Sudan, Wiederhold, Witt   +31 more
core   +1 more source

Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing

JAMA Neurology, 2018
Importance Identifying infectious causes of subacute or chronic meningitis can be challenging. Enhanced, unbiased diagnostic approaches are needed.
M. Wilson, B. O’Donovan, J. Gelfand, H. Sample, F. Chow, John P. Betjemann, M. Shah, M. Richie, M. Gorman, R. Hajj-Ali, L. Calabrese, K. Zorn, E. Chow, J. Greenlee, J. Blum, G. Green, Lillian M. Khan, Debarko Banerji, C. Langelier, C. Bryson-Cahn, Whitney E. Harrington, Whitney E. Harrington, J. Lingappa, Niraj M. Shanbhag, A. Green, B. Brew, B. Brew, A. Soldatos, L. Strnad, S. Doernberg, C. Jay, V. Douglas, S. Josephson, J. Derisi   +33 more
semanticscholar   +1 more source

Mortality from HIV‐associated meningitis in sub‐Saharan Africa: a systematic review and meta‐analysis

Journal of the International AIDS Society, 2020
HIV‐associated cryptococcal, TB and pneumococcal meningitis are the leading causes of adult meningitis in sub‐Saharan Africa (SSA). We performed a systematic review and meta‐analysis with the primary aim of estimating mortality from major causes of adult
M. Tenforde, A. Gertz, David S. Lawrence, Nicola K Wills, B. Guthrie, C. Farquhar, J. Jarvis   +6 more
semanticscholar   +1 more source

Global etiology of bacterial meningitis: A systematic review and meta-analysis

PLoS ONE, 2018
Bacterial meningitis is a global public health concern, with several responsible etiologic agents that vary by age group and geographical area. The aim of this systematic review and meta-analysis was to assess the etiology of bacterial meningitis in ...
Anouk M. Oordt-Speets, Renee Bolijn, R. V. van Hoorn, Amit Bhavsar, M. Kyaw   +4 more
semanticscholar   +1 more source

An overview of bacterial meningitis epidemics in Africa from 1928 to 2018 with a focus on epidemics “outside-the-belt”

BMC Infectious Diseases, 2020
Background Bacterial meningitis occurs worldwide but Africa remains the most affected continent, especially in the "Meningitis belt" that extends from Senegal to Ethiopia.
Serge Mazamay, J. Guégan, Neby Diallo, D. Bompangue, Eric Bokabo, J. Muyembe, N. Taty, Tonton Paul Vita, H. Broutin   +8 more
semanticscholar   +1 more source

Assessment of acute headache in adults - what the general physician needs to know. [PDF]

, 2018
Headache is common. Up to 5% of attendances to emergency departments and acute medical units are due to headache. Headache is classified as either primary (eg migraine, cluster headache) or secondary to another cause (eg meningitis, subarachnoid ...
Agrawal, Cappelen-Smith, Dodick, Hoffmann, Mac Grory, Macdonald, omi, Savitz, Sheikh, Solomon   +9 more
core   +1 more source

Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a large retrospective cohort of patients after solid organ transplantation [PDF]

, 2017
Background Cryptococcosis is the third most common invasive fungal infection in solid organ transplant (SOT) recipients. There are no nationally representative data describing the incidence, risk factors, and outcomes of cryptococcosis ...
George, Ige A, Olsen, Margaret A, Powderly, William G, Santos, Carlos A   +3 more
core   +2 more sources