Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report [PDF]
, 2018 Rationale: Tuberculous meningitis is a highly morbid, often fatal disease. Patient concern: We describe a case of an Italian child. Diagnoses: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and ...
Ajassa, Camilla +8 more
core +1 more source
Scientific Reports, 2018 Although rare in the U.S., outbreaks due to Neisseria meningitidis do occur. Rapid, early outbreak detection is important for timely public health response. In this study, we characterized U.S.
Melissa J. Whaley +10 more
doaj +1 more source
Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children [PDF]
, 2014 Extracellular heat shock protein 72 (Hsp72) is an endogenous danger signal and potential biomarker for critical illness in children. We hypothesized that elevated levels of extracellular Hsp72 in the cerebrospinal fluid (CSF) of children with suspected ...
Kernie, Steven G. +5 more
core +1 more source
Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa
BMC Infectious Diseases, 2019 Background We assessed the utility of a multi-target, real-time PCR assay for Bordetella pertussis detection and diagnosis in patients with severe respiratory illness (SRI), influenza-like illness (ILI), and asymptomatic controls.
Fahima Moosa +10 more
doaj +1 more source
The economic burden of RSV-associated illness in children aged < 5 years, South Africa 2011–2016
BMC Medicine, 2023 Background Data on the economic burden of RSV-associated illness will inform decisions on the programmatic implementation of maternal vaccines and monoclonal antibodies.
Jocelyn Moyes +11 more
doaj +1 more source
mSphere, 2022 Predictions of vaccine efficacy against Neisseria meningitidis serogroup B (NmB) disease are hindered by antigenic variability, limiting the representativeness of individual NmB isolates.
Alessandro Muzzi +8 more
doaj +1 more source
From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]
, 2017 In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core +3 more sources
Starting ART following cryptococcal meningitis:The optimal time has yet to be defined
Southern African Journal of HIV Medicine, 2013 Ever since the public sector rollout of antiretroviral therapy (ART) in 2004, the question of the optimal time to start ART following diagnosis of an opportunistic infection has aroused controversy among South African HIV clinicians and researchers.
T A Bicanic +3 more
doaj +1 more source
BMC Public Health, 2021 Background Describing contact patterns is crucial to understanding infectious disease transmission dynamics and guiding targeted transmission mitigation interventions. Data on contact patterns in Africa, especially South Africa, are limited.
Jackie Kleynhans +13 more
doaj +1 more source
Cryptococcal meningitis in HIV-infected patients: a longitudinal study in Cambodia. [PDF]
, 2010 To describe the frequency of diagnosis of cryptococcosis among HIV-infected patients in Phnom Penh, Cambodia, at programme entry, to investigate associated risk factors, and to determine the incidence of cryptococcal ...
Amornkul +24 more
core +2 more sources