Results 61 to 70 of about 398,631 (356)
Advanced Science, EarlyView.BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source
Molecular Identification of Meningitis/Septicemia Due to Streptococcus spp. in Greece (2015–2024)
DiagnosticsBackground/Objectives: Meningitis due to the species Streptococcus is a severe central nervous system infection caused by various microorganisms belonging to Streptococcus spp.
Constantinos Karamalis +5 more
doaj +1 more source
Useful residual hearing despite radiological findings suggestive of anacusis [PDF]
, 1999 A severe malformation of the inner ear, often referred to as severe labyrinthine dysplasia or common cavity deformity, consists of an absent or dilated cochlear basal coil, wide communication with the vestibule and a tapered internal acoustic meatus and ...
Bamiou, DE, Mahoney, CO, Sirimanna, T
core +1 more source
Advanced Science, EarlyView.ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan +7 more
wiley +1 more source
The Global Burden of Meningitis in Children: Challenges with Interpreting Global Health Estimates
Microorganisms, 2021 The World Health Organization (WHO) has developed a global roadmap to defeat meningitis by 2030. To advocate for and track progress of the roadmap, the burden of meningitis as a syndrome and by pathogen must be accurately defined.
Claire Wright +12 more
doaj +1 more source
Advanced Science, EarlyView.Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley +1 more source
BMC Infectious Diseases, 2018 Background Bacterial meningitis is a life-threatening infection that remains a public health concern. Bacterial meningitis is commonly caused by the following species: Neisseria meningitidis, Streptococcus pneumoniae, Listeria monocytogenes, Haemophilus ...
Nadav Topaz +6 more
doaj +1 more source
Pneumocéfalo Espontâneo Hipertensivo [PDF]
, 2019 info:eu-repo/semantics ...
Favas 1, C, Serôdio, J, Trindade, M
core +1 more source
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
Advanced Science, EarlyView.This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source
Vaccine implementation: Alaska 2017 [PDF]
, 2017 Bacterial meningitis is a serious disease that causes permanent dysfunction or death; adolescents and young adults carry the greatest risk. The national Advisory Committee on Immunization Practices (ACIP) has released vaccine recommendations that include
Hulstine, Amanda
core