Results 61 to 70 of about 498,582 (354)

Mortality from HIV‐associated meningitis in sub‐Saharan Africa: a systematic review and meta‐analysis

Journal of the International AIDS Society, 2020
HIV‐associated cryptococcal, TB and pneumococcal meningitis are the leading causes of adult meningitis in sub‐Saharan Africa (SSA). We performed a systematic review and meta‐analysis with the primary aim of estimating mortality from major causes of adult
M. Tenforde, A. Gertz, David S. Lawrence, Nicola K Wills, B. Guthrie, C. Farquhar, J. Jarvis   +6 more
semanticscholar   +1 more source

An overview of bacterial meningitis epidemics in Africa from 1928 to 2018 with a focus on epidemics “outside-the-belt”

BMC Infectious Diseases, 2020
Background Bacterial meningitis occurs worldwide but Africa remains the most affected continent, especially in the "Meningitis belt" that extends from Senegal to Ethiopia.
Serge Mazamay, J. Guégan, Neby Diallo, D. Bompangue, Eric Bokabo, J. Muyembe, N. Taty, Tonton Paul Vita, H. Broutin   +8 more
semanticscholar   +1 more source

Pneumococcal Serotype Identification by Capsular Sequence Typing (CST): A Modified Novel Approach for Serotyping Directly in Clinical Samples

Diagnostics, 2021
As almost 60–70% of Invasive Pneumococcal Disease (IPD) is identified by nonculture methods in Greece, serotyping is of high importance for the better monitoring of pneumococcal serotypes due to the availability of conjugate vaccines.
Nektarios Marmaras, Athanasia Xirogianni, Anastasia Papandreou, Efthymia Petinaki, Vana Papaevangelou, Maria Tsolia, Georgina Tzanakaki   +6 more
doaj   +1 more source

Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a large retrospective cohort of patients after solid organ transplantation [PDF]

, 2017
Background Cryptococcosis is the third most common invasive fungal infection in solid organ transplant (SOT) recipients. There are no nationally representative data describing the incidence, risk factors, and outcomes of cryptococcosis ...
George, Ige A, Olsen, Margaret A, Powderly, William G, Santos, Carlos A   +3 more
core   +2 more sources

Global etiology of bacterial meningitis: A systematic review and meta-analysis

PLoS ONE, 2018
Bacterial meningitis is a global public health concern, with several responsible etiologic agents that vary by age group and geographical area. The aim of this systematic review and meta-analysis was to assess the etiology of bacterial meningitis in ...
Anouk M. Oordt-Speets, Renee Bolijn, R. V. van Hoorn, Amit Bhavsar, M. Kyaw   +4 more
semanticscholar   +1 more source

Corticosteroids for managing tuberculous meningitis

Cochrane Database of Systematic Reviews, 2016
Background Tuberculous meningitis is a serious form of tuberculosis (TB) that affects the meninges that cover a person's brain and spinal cord. It is associated with high death rates and with disability in people who survive.
K. Prasad, Mamta B. Singh, H. Ryan
semanticscholar   +1 more source

Initial Experiences with Invasive Meningococcal Disease: Insights from Survivors and Their Caregivers

Infectious Diseases and Therapy
Introduction Invasive meningococcal disease (IMD) has a low incidence but is a life-threatening illness with a 10–15% mortality rate. Even with timely treatment, survivors may experience acute and long-term health complications.
Oscar Herrera-Restrepo, Nuzhat Afroz, Eliazar Sabater Cabrera, Matthew Reaney, France Ginchereau Sowell, Ramiya Kumar, Alicia Stillman, Patti Wukovits, Mariana Rodrigues, Sofia B. Pinto, Zeki Kocaata, Obinna Onwude   +11 more
doaj   +1 more source

Cronobacter, the emergent bacterial pathogen Enterobacter sakazakii comes of age; MLST and whole genome sequence analysis [PDF]

, 2014
Background: Following the association of Cronobacter spp. to several publicized fatal outbreaks in neonatal intensive care units of meningitis and necrotising enterocolitis, the World Health Organization (WHO) in 2004 requested the establishment of a ...
Dickins, B, Forsythe, SJ, Jolley, KA
core   +2 more sources

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma, Ilo Leppik, Thomas Henry, Thaddeus Walczak, Sima Patel, Robert McGovern   +5 more
wiley   +1 more source