Methionine enkephalin(MENK) upregulated memory T cells in anti-influenza response [PDF]
BMC Immunology, 2023 Novel prophylactic drugs and vaccination strategies for protection against influenza virus should induce specific effector T-cell immune responses in pulmonary airways and peripheral lymphoid organs.
Jing Tian +6 more
doaj +5 more sources
Methionine enkephalin upregulates toll-like receptors in macrophages to suppress severe fever with thrombocytopenia syndrome virus infection [PDF]
Frontiers in ImmunologyBackgroundSevere fever with thrombocytopenia syndrome virus (SFTSV) is a newly identified tick-borne virus with a high case fatality rate. Currently, no specific antiviral drugs are available for its treatment.
Jing Tian +7 more
doaj +3 more sources
Methionine enkephalin upregulates the immune function of RAW264.7 cells to inhibit the infection of Nelson Bay orthoreoviruses [PDF]
Scientific ReportsPreliminary research has found that MENK can upregulate the antiviral state of macrophages to inhibit influenza virus infection. To further study the immunomodulatory mechanism of MENK in macrophages against reovirus, we used RNA-Seq technology to ...
Xiaoli Tao +4 more
doaj +3 more sources
Red Blood Cell Distribution Width (RDW) as Predictor of the Clinical Course and Mortality in Patients With Acute Respiratory Distress Syndrome (ARDS): A Retrospective Study [PDF]
Health Science ReportsBackground and Aims Evidence on the prognostic value of red blood cell distribution width (RDW) in critically ill patients with acute respiratory distress syndrome (ARDS) is limited.
Anna Kirsch +8 more
doaj +3 more sources
Tumor associated macrophages in gastric cancer dual roles in immune evasion and clinical implications for targeted therapy [PDF]
Frontiers in ImmunologyGastric cancer (GC) remains a major global health burden with persistently high mortality despite therapeutic advances. Accumulating evidence highlights the pivotal role of tumor-associated macrophages (TAMs) in orchestrating gastric tumor progression ...
Chang Wang +6 more
doaj +2 more sources
PEPI Lab: a flexible compact multi-modal setup for X-ray phase-contrast and spectral imaging [PDF]
Scientific Reports, 2023 This paper presents a new flexible compact multi-modal imaging setup referred to as PEPI (Photon-counting Edge-illumination Phase-contrast imaging) Lab, which is based on the edge-illumination (EI) technique and a chromatic detector.
Luca Brombal +4 more
doaj +2 more sources
The effects of the COVID-19 pandemic on pediatric dog bite injuries [PDF]
Injury EpidemiologyBackground/objective Shortly after the onset of the COVID Pandemic, when many schools and outside activities were suspended, dog adoption rates increased. It is unknown if increased dog adoption rates along with stay-at-home orders resulted in changes to
Paul T. Menk +2 more
doaj +2 more sources
Serum neurofilament light chain in COVID-19 and the influence of renal function [PDF]
European Journal of Medical Research, 2023 COVID-19 is associated with various neurological symptoms. Serum neurofilament light chain (sNfL) is a robust marker for neuroaxonal injury. Recent studies have shown that elevated levels of sNfL are associated with unfavorable outcome in COVID-19 ...
Peter Körtvelyessy +9 more
doaj +3 more sources
Antimicrobial Peptide Arsenal Predicted from the Venom Gland Transcriptome of the Tropical Trap-Jaw Ant Odontomachus chelifer [PDF]
Toxins, 2023 With about 13,000 known species, ants are the most abundant venomous insects. Their venom consists of polypeptides, enzymes, alkaloids, biogenic amines, formic acid, and hydrocarbons.
Josilene J. Menk +6 more
doaj +2 more sources
Effects of the primary lung infection on outcomes in patients with severe ARDS treated with ECMO: a retrospective analysis [PDF]
Frontiers in MedicineIntroductionAcute respiratory distress syndrome (ARDS) requiring veno-venous extracorporeal membrane oxygenation (vvECMO) remains associated with high mortality.
Martin Mirus +19 more
doaj +2 more sources