Results 161 to 170 of about 91,813 (297)

FDA's 2025 removal of black box warnings on menopausal hormone therapy. [PDF]

Ann Med Surg (Lond)
Zeeshan F, Saqlain A.
europepmc   +1 more source

Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization

Macromolecular Rapid Communications, EarlyView.
Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou, John T. Leman, Harper Serringer, Ke Xia, Christopher N. LaFratta, Chaitanya Ullal, Edmund F. Palermo   +6 more
wiley   +1 more source

Menopausal hormone therapy for breast cancer patients: what is the current evidence? [PDF]

Menopause
Glynne S, Simon J, Branson A, Payne S, Newson L, Manyonda I, Cleator S, Douek M, Usiskin S, Tobias JS, Vaidya JS.   +10 more
europepmc   +1 more source

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

Long-term amyloid PET and MRI outcomes in a menopausal hormone therapy trial. [PDF]

Alzheimers Dement
Kantarci K, Kara F, Tosakulwong N, Fought AJ, Schwarz CG, Senjem ML, Kendall-Thomas J, Min P, Lowe VJ, Jack CR, Kapoor E, Fields JA, Bailey KR, James TT, Faubion L, Lobo RA, Manson JE, Pal L, Hammers DB, Brinton EA, Malek-Ahmadi M, Cedars MI, Naftolin FN, Santoro N, Miller VM, Harman SM, Dowling NM, Gleason CE.   +27 more
europepmc   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

Neuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher, Anna F. Dominiczak, Luis M. Garcia‐Segura, Nobuhiro Harada, J. B. Hutchison, James M. Mullin, Delyth Graham, Peter O'Shaughnessy, Hilary Victoria O. Carswell   +8 more
wiley   +1 more source

Improvements in interoceptive sensibility, pain and functional clinical outcome measures after participation in an interdisciplinary pain management program

PM&R, EarlyView.
Abstract Background Altered interoception, the sense of signals from inside the body, is linked to chronic pain. No studies to date have examined whether interoceptive sensibility, one's self‐reported beliefs about the body and tendencies to be internally focused, changes following participation in an interdisciplinary pain management program (IPMP ...
Stephanie Voss, Shannon La Penna, Alison Yum, Neha P. Gothe, Christine M. Gagnon   +4 more
wiley   +1 more source

Menopausal Hormone Therapy-Risks, Benefits and Emerging Options: A Narrative Review. [PDF]

Int J Mol Sci
Arnautu AM, Nimigean VR, Nacea-Radu CA, Tilici DM, Paun DL.   +4 more
europepmc   +1 more source

Female hormonal exposures and neuromyelitis optica symptom onset in a multicenter study [PDF]

, 2017
Alvarez, Enrique, Cross, Anne H, et al,
core   +2 more sources

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source