Results 61 to 70 of about 2,260,319 (245)

Lactobacillus johnsonii attenuates ovarian aging by remodeling the gut–ovary axis

iMetaOmics, EarlyView.
Aging is accompanied by a reduced abundance of L. johnsonii and ovarian decline. Supplementation with L. johnsonii elevates microbial IPA production via the LdhA enzyme and commensal bacteria. IPA activates the AhR/YAP signaling axis, promoting YAP nuclear translocation and inducing the expression of downstream target genes CYR61 and CTGF. This cascade
Jiamin He, Qiwen Wang, Luyi Chen, Yadong Qi, Dingjiacheng Jia, Jilei Xu, Qingyi Wang, Yao Jiang, Jian Zhou, Yong Sun, Ruochen Yan, Lan Wang, Tongyao Hou, Zheng Kuang, Min Jin, Liangjing Wang, Shujie Chen   +16 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Evaluation of association between psychological stress level during menopausal transition period and serum estrogen level among middle-aged women: A cross-sectional study

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: Menopause is a gradual transition from reproductive to non-reproductive phase in women during which there is substantial fluctuation in estrogen or estrogen deficiency.
Ashwini Kishan, Shailaja S Moodithaya, Amrit M Mirajkar   +2 more
doaj   +1 more source

A study on the prevalence of menopausal symptoms and its impact on quality of life among women aged 41 to 60 years in a rural area

Journal of Family Medicine and Primary Care
Introduction: Menopausal transition has an impact on health and well-being of women. Majority of rural women employed in manual labour, suffer from severe menopausal symptoms.
R A Roshini, A. Meriton Stanly, Varadarajan Samya   +2 more
doaj   +1 more source

Menopausal transition and early postmenopause in women with obesity of various types and degrees [PDF]

РМЖ. Мать и дитя, 2019
Menopausal transition and early postmenopause in women with obesity of various types and degrees E.A. Sandakova1, I.G. Zhukovskaya2 1 Academician E.A.
Sandakova E.A., Zhukovskaya I.G.
doaj  

Psychosomatic and vasomotor symptom changes during transition to menopause

Menopause Review, 2019
Menopause is the condition in which the gradual decline in ovarian function finally leads to the permanent cessation of menstruation. Oestrogen deficiency may cause early symptoms during the menopausal transition and late symptoms after menopause ...
Areti Augoulea, Michalis Moros, Aikaterini Lykeridou, George Kaparos, Rallou Lyberi, Konstantinos Panoulis   +5 more
doaj   +1 more source

Epilepsy surgery through a reproductive lifespan lens

Epilepsia, EarlyView.
Aisha A. Abdulrazaq, Dorothee Kasteleijn‐Nolst Trenite, Torbjörn Tomson   +2 more
wiley   +1 more source

Comparison of Continuous‐Time Random Walk and Fractional Order Calculus Diffusion Models for Preoperative Breast Lesion Characterization: Diagnosis, Biomarker Prediction and Molecular Subtyping

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Accurate preoperative characterization of breast lesions is important for individualized management. The conventional monoexponential (Mono) model has limited ability to capture the complex microstructure of lesions. Non‐Gaussian diffusion models, including continuous‐time random walk (CTRW) and fractional‐order calculus (FROC), may
Yimeng Cao, Shaomin Li, Zhexuan Yang, Xueyan Liu, Shifang Tan, Tian Ren, Wenjia Wang, Haiyang Li, Xingzhi Chen, Xin Zhao, Meiying Cheng   +10 more
wiley   +1 more source

Swedish women's experiences of menopausal transition : A focus group study

, 2023
Objective: The aim of this study was to examine women's experience of menopausal transition and their expectations and wishes for support from healthcare.
Brorsson, Annika, Lycke, Anette, Brorsson, Annika,, Lycke, Anette,, Lund University.   +4 more
core   +1 more source