Results 41 to 50 of about 44,752 (306)

Cohort profile: the avon longitudinal study of parents and children: ALSPAC mothers cohort [PDF]

, 2013
The Avon Longitudinal Study of Children and Parents (ALSPAC) was established to understand how genetic and environmental characteristics influence health and development in parents and children.
A. Boyd, A. Fraser, A. Ness, Alati, C. Macdonald-Wallis, Chen, Chittleborough, Cookson, D. A. Lawlor, Davey Smith, Deave, Dudding, Evans, FARROW, Fergusson, G. Davey Smith, Golding, Golding, Golombok, Hibbeln, J. Golding, J. Henderson, J. Macleod, Jeffreys, K. Tilling, L. Molloy, Lawlor, Lawlor, Leary, Lewis, Liu, Loos, Macdonald-Wallis, Macdonald-Wallis, Macdonald-Wallis, Macleod, Micali, Northstone, O'Connor, O'CONNOR, O'Connor, O'Connor, Perry, Rogers, S. M. Nelson, S. Ring, Shugart, Smith, Weedon, Willer, Zammit   +50 more
core   +2 more sources

Menopausal status, transition, and age at menopause with accelerated biological aging across multiple organ systems: findings from two cohort studies

BMC Medicine
Background Biological aging is a heterogeneous process that varies across organs and systems. The dynamic hormonal changes during the menopausal transition may have profound and organ-specific impacts on biological aging.
Yi Xiang, Qiong Meng, Zitong Huang, Ning Zhang, Yuan Zhang, Xianbin Ding, Jianhong Yu, Baimakangzhuo, Leilei Liu, Xiong Xiao, Xing Zhao   +10 more
doaj   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Prevalence and management of menopausal symptoms in malaysian women during peri and post menopause [PDF]

, 2015
Women upon reaching menopause often silently suffer debilitating physical and psychological symptoms. The peri and postmenopausal period constitutes a challenging transition time for women’s health, and good menopausal health is a crucial aspect in ...
Alias, Norma, Haron, Habibah @ Norehan, Harun, Hafizah, Kamaruddin, Azlina   +3 more
core  

Prospective study to compare antibiosis versus the association of N-acetylcysteine, D-mannose and morinda citrifolia fruit extract in preventing urinary tract infections in patients submitted to urodynamic investigation [PDF]

, 2017
BACKGROUND: The abuse of antimicrobical drugs has increased the resistance of microorganisms to treatments, thus to make urinary tract infections (UTIs) more difficult to eradicate.
Al Rawashdah, S, AL SALHI, Yazan, Carbone, Antonio, Coppola, Gianpietro, Fuschi, Andrea, Leto, Antonino, Maruccia, S, Maurizi, Angela, Mele, Rita, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Velotti, Gennaro, Zanello, Pp   +12 more
core   +2 more sources

The menopause transition: an update [PDF]

Human Reproduction Update, 2002
The menopausal transition is an area of active clinical investigation and epidemiological research. Recent results from several worldwide cohorts of women are beginning to provide a paradigm by which to explain the epidemiological and clinical manifestations of the ovarian process of follicle attrition.
openaire   +2 more sources

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Anxiety and depression in menopausal transition: A hospital-based study from Kashmir

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2020
Background: Menopausal transition (MT) is the period of irregular menstrual activity which directly precedes menopause and is characterized by widely fluctuating hormone levels and reproductive, metabolic, and psychological disturbances.
Shabir Ahmad Dar, Zaid Ahmad Wani, Bilal Ahmad Bhat, Shanoo Sheikh, Junaid Nabi, Aaliya Khanam, Deeba Nazir, Mudasir Nazir   +7 more
doaj   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Vascular function and cardiovascular risk factors in women with severe flushing [PDF]

, 2011
Background: Seventy per cent of postmenopausal women suffer from hot flushes causing significant morbidity in 25%. Oestrogen replacement provides symptom relief, but its use has declined following safety issues and there is, as yet, no good alternative ...
Andrikoula, Bechlioulis, Brockie, Caballero, Ferrell, Freedman, Freeman, Gambacciani, Ginsburg, Huang, Keating, Khan, Khan, Kronenberg, Kubli, Leal, Lerman, Lobo, Martin, Modena, Morris, Nilsson, Noon, Ramsay, Ramsay, Sattar, The Emerging Risk Factors Collaboration, Thurston, Wardell   +28 more
core   +1 more source