Results 31 to 40 of about 2,260,319 (245)

Menopausal hormone therapy prescription strategies in patients of transitional age

Клинический разбор в общей медицине
Menopausal transition is a special period of reproductive aging associated with a broad spectrum of endocrine and metabolic alterations contributing to the complete remodeling of the physiological body functioning patterns.
Mekan R. Orazov, Viktor E. Radzinskiy, Vera E. Balan, Evgeniy D. Dolgov   +3 more
doaj   +1 more source

DOES PHYSICAL ACTIVITY MODULATE CHANGES IN BLOOD PRESSURE AND BODY ADIPOSITY DURING THE MENOPAUSAL TRANSITION?

, 2021
DOES PHYSICAL ACTIVITY MODULATE CHANGES IN BLOOD PRESSURE AND BODY ADIPOSITY DURING THE MENOPAUSAL ...
H-K Juppi (17175622), TH Tammelin (14376027), S Sipila (17175625), M Hyvarinen (17175619), S Taskinen (13575202), JE Karppinen (15869816), Timo Rantalainen (13097757), EK Laakkonen (15869819)   +7 more
core   +1 more source

Menopausal Transition Is Not Associated with Dietary Change in Swiss Women [PDF]

, 2021
BACKGROUND Adherence to a healthy diet could contribute to maintaining adequate health throughout the menopausal transition, but data are scarce. OBJECTIVE We evaluated the association between menopausal status and changes in dietary intake in ...
Oscar H Franco, Taulant Muka, Raguindin, Peter Francis, Bally, Lia, Franco, Oscar H, Grisotto, Giorgia, Marija Glisic, Lia Bally, Muka, Taulant, Arjola Bano, Bano, Arjola, Giorgia Grisotto, Peter Francis Raguindin, Marques-Vidal, Pedro, Glisic, Marija, Pedro Marques-Vidal, Grisotto, G., Glisic, M., Bano, A., Bally, L., Franco, O.H., Raguindin, P.F., Marques-Vidal, P., Muka, T.   +23 more
core   +3 more sources

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Menopausal status, transition, and age at menopause with accelerated biological aging across multiple organ systems: findings from two cohort studies

BMC Medicine
Background Biological aging is a heterogeneous process that varies across organs and systems. The dynamic hormonal changes during the menopausal transition may have profound and organ-specific impacts on biological aging.
Yi Xiang, Qiong Meng, Zitong Huang, Ning Zhang, Yuan Zhang, Xianbin Ding, Jianhong Yu, Baimakangzhuo, Leilei Liu, Xiong Xiao, Xing Zhao   +10 more
doaj   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Sleep During Menopausal Transition: A 6-Year Follow-Up [PDF]

, 2017
Study Objectives: Menopausal transition is associated with increased dissatisfaction with sleep, but the effects on sleep architecture are conflicting. This prospective 6-year follow-up study was designed to evaluate the changes in sleep stages and sleep
Tarja Saaresranta, Polo-Kantola, Paivi, Päivi Polo-Kantola, Heinonen, Olli J., Himanen, Sari-Leena, Kurki, Samu, Eero Huupponen, Lampio, Laura, Saaresranta, Tarja, Olli J. Heinonen, Laura Lampio, Janne Engblom, Sari-Leena Himanen, Samu Kurki, Huupponen, Eero, Engblom, Janne, Olli Polo, Polo, Olli   +17 more
core   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

Animal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad, Hubdar Ali Kolachi, Jesse Oluwaseun Ayantoye, Xiaomeng Zhang, Muhammad Usman Mehmood, Rajilan Hilali Shanga, Pengcheng Wan, Xueming Zhao   +7 more
wiley   +1 more source

Metabolic syndrome in menopausal transition: Isfahan Healthy Heart Program, a population based study

Diabetology & Metabolic Syndrome, 2010
Introduction There is a remarkable increase in cardiovascular disease after menopause. On the other hand, metabolic syndrome as a collection of risk factors has a known effect on cardiovascular diseases.
Heidari Ramin, Sadeghi Masoumeh, Talaei Mohammad, Rabiei Katayoun, Mohammadifard Noushin, Sarrafzadegan Nizal   +5 more
doaj   +1 more source