Results 101 to 110 of about 272,065 (310)

A Thematic Analysis of Mental Illness in New Zealand News Articles

open access: yes, 2014
Mental illness is one of the main reasons for disability in the western world with one in five individuals being classed as mentally ill during some time in their life.
Fernandez, Brett
core  

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

FAMILY VIOLENCE

open access: yesPravo, 2010
At issue is family violence which exists as a phenomenon but is not sufficiently focused on in many countries.There are still countries in vich family is not(according to the low) a crime.Family violence is behavior in vich one family member endangers ...
Milan Počuča
doaj  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Understanding object-oriented source code from the behavioural perspective

open access: yes, 2005
Comprehension is a key activity that underpins a variety of software maintenance and engineering tasks. The task of understanding object-oriented systems is hampered by the fact that the code segments that are related to a user-level function tend to be ...
Walkinshaw, N., Roper, M., Wood, M.
core  

'Paperwork': Its implications for community mental health nurses' practice [PDF]

open access: yes, 2011
This study aims to examine the real life documentary practices of community mental health nurses to enable a better understanding of the impact of paperwork on their nursing practice.The work on the research proposal was supported by the Community ...
Deacon, Maureen
core  

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

open access: yesAdvanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu   +19 more
wiley   +1 more source

Sharing Developers' Mental Models through Source Code Annotations [PDF]

open access: yesAnnals of computer science and information systems, 2015
Matúš Sulír, Milan Nosáľ
doaj   +1 more source

Volunteering in the care of people with severe mental illness: a systematic review

open access: yes, 2012
Background Much of the literature to date concerning public attitudes towards people with severe mental illness (SMI) has focused on negative stereotypes and discriminatory behaviour.
Hallett Claudia   +11 more
core   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

open access: yesAdvanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis   +32 more
wiley   +1 more source

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