Results 121 to 130 of about 272,065 (310)

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Full‐Stack Architectures for Intelligent Brain‐Computer Interfaces

Advanced Science, EarlyView.
System‐level overview of brain–computer interfaces (BCIs), illustrating the integration of neural signal acquisition, wireless transmission, and adaptive decoding. Advanced electrode, tissue interfaces, energy‐efficient communication, and robust algorithms collectively enable stable signal quality, real‐time processing, and closed‐loop operation ...
Hee Kyu Lee, Hyun Bin Kim, Sang Uk Park, Janghoon Joo, Jinhong Min, Geumbee Lee, Joohoon Kang, Hyoyoung Jeong, Jae‐Young Yoo, Sang Min Won   +9 more
wiley   +1 more source

A survey of occupational therapy practitioners in mental health

, 1998
As part of the College of Occupational Therapists’ Mental Health Project, a survey of occupational therapists practising in mental health in the UK was conducted.
Richards, G, Chacksfield, J, Craik, C
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Commentary on the Alaska Revised Criminal Code (Ch. 166, SLA 1978) and Errata to the Commentary [PDF]

, 1978
Originally published in Senate Journal Supplements 47 and 48, Tenth Alaska Legislature (1977–1978). As of 1975, Alaska’s criminal laws were based primarily on Oregon criminal statutes as they existed at the close of the nineteenth century, with new ...
Alaska Criminal Code Revision Subcommission
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Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins

Advanced Science, EarlyView.
Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo, Xia Zhong, Petros Koutrakis, Carolina L. Zilli Vieira, Feifei Si, Yaqi Wang, Xinyao Lian, Yi Fan, Zhaokun Wang, Shaodan Huang, Jing Li   +10 more
wiley   +1 more source

The barriers and facilitators of supporting self care in Mental Health NHS Trusts

, 2010
Mental health presents challenges to the concept of self care – mental health services have been especially reluctant to share responsibility with service users, and some service users are reluctant to engage with services that they feel are ...
Simons, Lucy, White, Sarah, Minogue, Virginia, Lucock, Mike, Betton, Victoria, Green, Katherine, Miller, Stephen, Gillard, Steve, Holt, Barrie, Turner, Kati   +9 more
core  

A psychoanalytic investigation of transference management in the Irish adult public mental health services [PDF]

, 2012
Mental health is a pressing issue for society with approximately 700,000 of the Irish population being affected by a mental health problem over the course of their lives.
Moore, Gerard
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Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories

eLife
Spatial periodicity in grid cell firing has been interpreted as a neural metric for space providing animals with a coordinate system in navigating physical and mental spaces.
Rebecca RG, Giorgio A Ascoli, Nate M Sutton, Holger Dannenberg   +3 more
doaj   +1 more source

Equipes multiprofissionais em saúde mental: problemas e desafios para o Serviço Social. [PDF]

, 2014
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Serviço Social.O presente trabalho de conclusão de curso trata-se de um trabalho monográfico realizado a partir de uma revisão bibliográfica, que tem por objetivo analisar o
Jordão, Aline Evanise
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