Results 91 to 100 of about 5,076,978 (312)

Unveiling chiral amino acid alterations and glycine dysregulation in late-life depression through targeted metabolomics

open access: yesFrontiers in Psychiatry
BackgroundLate-life depression (LLD) is a major depressive disorder that is highly prevalent among older people, and there are currently no validated biomarkers for the diagnosis and treatment of LLD.
Mingxia Liu   +8 more
doaj   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Biopsychosocial predictors and trajectories of work participation after transdiagnostic occupational rehabilitation of participants with mental and somatic disorders: a cohort study [PDF]

open access: gold, 2018
Karen Walseth Hara   +7 more
openalex   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Erratum to: A qualitative study of perceived needs and factors associated with the quality of care for common mental disorders in patients with chronic diseases: the perspective of primary care clinicians and patients [PDF]

open access: gold, 2016
Pasquale Roberge   +17 more
openalex   +1 more source

Comorbidity of mental and musculoskeletal disorders in ageing women: A data linkage study using national registries [PDF]

open access: hybrid, 2021
Jeremi Heikkinen   +6 more
openalex   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

Suicidal risk is associated with hyper-connections in the frontal-parietal network in patients with depression

open access: yesTranslational Psychiatry
Suicide is a complex behavior strongly associated with depression. Despite extensive research, an objective biomarker for evaluating suicide risk precisely and timely is still lacking.
Yanping Ren   +13 more
doaj   +1 more source

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