Results 51 to 60 of about 5,076,978 (312)

Prophylactic Management of Vestibular Migraine: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Vestibular migraine (VM) is a neurological disorder characterized by episodic vertigo in patients with migraine, contributing to substantial functional impairment. Although VM is relatively common, a consensus on effective prophylactic treatments is lacking.
Hussain Ali Almohammed, Husna Irfan Thalib, Kawthar Faisal Kushara, Bushra Wadi Bin Saddiq, Bayan Mohammed Khair Al Zoabi, Tanveer Nidal Khan, Ahmed Salah Morad, Rimas Warid Aljuaid, Lamyaa Mohammed Gharawi, Shahad Jawdat Alsaygh, Mable Pereira, Shaima Abuhulayqah   +11 more
wiley   +1 more source

LC–MS/MS quantification of 20(S)-protopanaxadiol in complex biological matrices for bioanalytical method validation and pharmacokinetic analysis

Scientific Reports
20(S)-Protopanaxadiol (PPD) is a saponin derivative of ginsenoside, with more potent biological and pharmacological activities than Rg3 and Rh2. The lack of ionizable centers leads to low mass spectrometry reactions and internal cleavage of three ...
Pengfei Li, Shanshan Liu, Hongyan Zhuang, Mengxi niu, Fei Pan, Nan Wang, Sha Sha, Qian Wang, Jing Wang   +8 more
doaj   +1 more source

Incidence Rates and Cumulative Incidences of the Full Spectrum of Diagnosed Mental Disorders in Childhood and Adolescence.

JAMA psychiatry, 2019
Importance Knowledge about the epidemiology of mental disorders in children and adolescents is essential for research and planning of health services.
S. Dalsgaard, E. Thorsteinsson, B. Trabjerg, J. Schullehner, O. Plana-Ripoll, Isabell Brikell, T. Wimberley, Malene Thygesen, K. B. Madsen, Allan Timmerman, D. Schendel, J. Mcgrath, P. Mortensen, C. Pedersen   +13 more
semanticscholar   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Sociodemographic, clinical and treatment characteristics of current rapid-cycling bipolar disorder: a multicenter Chinese study

International Journal of Bipolar Disorders
Background Rapid cycling bipolar disorder (RCBD), characterized by four or more episodes per year, is a complex subtype of bipolar disorder (BD) with poorly understood characteristics.
Jin-jie Xu, Xue-quan Zhu, Shuang Liu, Lu-yu Ding, Bing-bing Fu, Cong-cong Sun, Yan-li Pan, Wei Wang, Ling Zhang   +8 more
doaj   +1 more source

Exploring Comorbidity Within Mental Disorders Among a Danish National Population

JAMA psychiatry, 2019
Importance Individuals with mental disorders often develop comorbidity over time. Past studies of comorbidity have often restricted analyses to a subset of disorders and few studies have provided absolute risks of later comorbidity.
O. Plana-Ripoll, C. Pedersen, Y. Holtz, M. Benros, S. Dalsgaard, P. de Jonge, C. Fan, L. Degenhardt, Andrea Ganna, A. Greve, J. Gunn, K. Iburg, L. Kessing, Brian K. Lee, C. Lim, O. Mors, M. Nordentoft, Anders Prior, A. Roest, S. Saha, A. Schork, James G. Scott, K. Scott, T. Stedman, H. Sørensen, T. Werge, H. Whiteford, T. Laursen, E. Agerbo, R. Kessler, P. Mortensen, J. Mcgrath   +31 more
semanticscholar   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Factors associated with the frequency of manic and depressive episodes in bipolar disorder: a multicenter study in China

BMC Psychiatry
Background Mania and depression are the predominant mood episodes in bipolar disorder (BD), and their frequency significantly affects the long-term prognosis of patients. Method This is a multicenter, longitudinal cohort study in China.
Shuang Liu, Jin-Jie Xu, Xue-Quan Zhu, Bing-Bing Fu, Yan-Li Pan, Cong-Cong Sun, Sheng Li, Gao-Ming Xie, Ling Zhang   +8 more
doaj   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source

Clinical characteristics of 217 Chinese cases with depersonalization/derealization disorder

BMC Psychiatry
Depersonalization/derealization disorder (DPD) is a prevalent yet inadequately understood clinical condition characterized by a recurrent or persistent sense of unreality.
Mingkang Song, Sisi Zheng, Nan Song, Hong Zhu, Yuan Jia, Zhiqing Dai, Xinzi Liu, Ziyao Wu, Yuhang Duan, Zhiyuan Huang, Jindong Chen, Hongxiao Jia   +11 more
doaj   +1 more source