Results 31 to 40 of about 2,169,216 (305)

Targeting the Beast Along My Illness Trajectory: A Qualitative Study of Females With Triple-Negative Breast Cancer

open access: yesJournal of Patient Experience
Breast cancer subtypes differ in prevalence, aggressiveness, and availability of targeted therapies. However, research often examines the lived experiences of individuals with breast cancer collectively.
Josianne Scerri PhD   +2 more
doaj   +1 more source

Self-Stigma in Patients with Endogenous Mental Disorders: A Cross-Sectional Comparative Study [PDF]

open access: yesConsortium Psychiatricum
BACKGROUND: Self-stigma remains one of the most vexing issues in psychiatry. It complicates the treatment and social functioning of patients with endogenous psychiatric disorders. Identifying the specific features of self-stigma depending on the type and
Tatiana Solokhina   +7 more
doaj   +1 more source

Preconception origins of perinatal maternal mental health

open access: yes, 2021
Perinatal maternal symptoms of depression and anxiety compromise psychosocial function and influence developmental outcomes in the offspring. The onset of symptoms remains unclear with findings that suggest a preconceptual origin. We addressed this issue
Chong, Yap Seng   +10 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mental Health Nurses’ and Allied Health Professionals’ Individual Research Capacity and Organizational Research Culture: A Comparative Study

open access: yesSAGE Open Nursing
Introduction Healthcare professionals have development needs related to their consumption, use, and practice of clinical research. Little is known about these issues in mental health services specifically.
Geoffrey L. Dickens PhD, MA, RMN   +4 more
doaj   +1 more source

Stable structure, shifting links: How depression–anxiety symptom networks reconfigure from pregnancy to postpartum

open access: yesEuropean Psychiatry
Background Network analysis was employed to test whether the overall pattern of depressive–anxious symptom connections remains stable or whether specific symptom-to-symptom links shift from pregnancy to postpartum.
Alberto Stefana   +5 more
doaj   +1 more source

A multi-country survey of the socio-demographic factors associated with adherence to COVID-19 preventive measures during the first wave of the COVID-19 pandemic

open access: yesBMC Public Health, 2023
Background Health behaviours are influenced by individual characteristics including age, gender, education and economic level. This study aimed to assess the associations between individual-level determinants and adherence to COVID-19 preventive measures.
Morenike Oluwatoyin Folayan   +15 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

ABC of mental health: Mental health and the law [PDF]

open access: yesBMJ, 1997
The law relating to medical practice in general, and mental health in particular, is complex. This article provides a summary of the laws applying in England and Wales. Certain mental disorders are the only medical conditions for which the law permits treatment without the consent of the patient, but this can be undertaken only in a hospital or ...
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Home - About - Disclaimer - Privacy