Results 51 to 60 of about 4,652,557 (359)

Multifactorial, biomarker-based model for assessing the state of patients with schizophrenia

open access: yesБюллетень сибирской медицины
Relevance. Objective comparison of biological markers and real clinical presentation is especially difficult in mental disorders, which are classified according to a large number of diagnostic criteria and a wide variety of symptoms.
E. G. Cheremnykh   +8 more
doaj   +1 more source

Association between polymorphism of the NEDD4 gene and cognitive dysfunction of schizophrenia patients in Chinese Han population

open access: yesBMC Psychiatry, 2019
Background Schizophrenia is a complex psychiatric disorder with unknown etiology. A number of recent studies have shown that the polymorphism of the neural precursor cell expressed developmentally down-regulated 4 (NEDD4) gene is associated with a ...
Chao Han   +6 more
doaj   +1 more source

An Assessment of Mental Health Services for Veterans in the State of Texas [PDF]

open access: yes, 2015
This report describes the complex challenges faced by veterans and their families in seeking, navigating, and attaining adequate mental health care in Texas.
Eaton, David   +3 more
core  

Fixel‐Based Analysis of Diffusion Imaging as a Quantitative Marker of Disease State in Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous neurodegenerative diseases causing progressive deterioration and reduced quality of life. Therapeutic advances have been limited by a lack of sensitive anatomic, functional, or diffusion imaging‐based biomarkers.
David J. Arpin   +11 more
wiley   +1 more source

CONNECTION BETWEEN ORAL DISEASES AND MENTAL HEALTH

open access: yesRomanian Journal of Oral Rehabilitation
Extensive epidemiological research has been conducted by the World Health Organization (WHO) in recent years to identify and validate associations between mental problems and physical illnesses.
Oana Cristina Cretu   +6 more
doaj   +1 more source

Plasma complement C3 and C3a are increased in major depressive disorder independent of childhood trauma

open access: yesBMC Psychiatry, 2022
Background Dysregulated complement system is linked to pathophysiology of major depressive disorder (MDD). Childhood trauma has been associated with an increased incidence of adult depression via a putative mechanism of immune activation.
Xianmei Luo   +5 more
doaj   +1 more source

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro   +12 more
wiley   +1 more source

Minocycline as adjunctive treatment for treatment-resistant depression: study protocol for a double blind, placebo-controlled, randomized trial (MINDEP2)

open access: yesBMC Psychiatry, 2020
Background Available evidence suggests that adjunctive treatment with immunomodulatory medications may be effective in the treatment of major depressive disorder (MDD).
Muhammad Ishrat Husain   +14 more
doaj   +1 more source

Mental health nurses’ attitudes, experience, and knowledge regarding routine physical healthcare:systematic, integrative review of studies involving 7,549 nurses working in mental health settings [PDF]

open access: yes, 2019
Background: There has been a recent growth in research addressing mental health nurses’ routine physical healthcare knowledge and attitudes. We aimed to systematically review the empirical evidence about i) mental health nurses’ knowledge, attitudes, and
Atlantis, Evan   +4 more
core   +6 more sources

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova   +5 more
wiley   +1 more source

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