Results 61 to 70 of about 1,732,130 (259)

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

Child and Adolescent Mental Health Services (CAMHS) – CHO 1 2017 Inspection Report [PDF]

, 2018
In 2017, the Inspector of Mental Health Services sought information from each Community Healthcare Organisation (CHO) about Child and Adolescent Mental Health Services (CAMHS) in their area. Information was collected by questionnaire on 15 September 2017
Mental Health Commission (MHC)
core  

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Body context and posture affect mental imagery of hands. [PDF]

PLoS ONE, 2012
Different visual stimuli have been shown to recruit different mental imagery strategies. However the role of specific visual stimuli properties related to body context and posture in mental imagery is still under debate.
Silvio Ionta, David Perruchoud, Bogdan Draganski, Olaf Blanke   +3 more
doaj   +1 more source

Mental Health Commission Annual Report 2016 [PDF]

, 2017
During 2016, the Commission in association with the Executive continued its work in accordance with the Mental Health Act 2001 and under the direction of its Strategic Plan.
Mental Health Commission (MHC)
core  

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Mental-rotation performance.

, 2021
Percent correct in the mental-rotation task displayed as a function of participant group (cisfemale, cismale, transmale) and hemisphere (left, right). Error bars indicate standard error of the mean.
E. Darcy Burgund (11805563)
core   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Quantum‐Like Dynamics in Whole‐Brain Models of the Human Connectome

Advanced Science, EarlyView.
Quantum‐like dynamics in the human brain. The level of quantum‐like behavior in a non‐quantum system of coupled oscillators is regulated by the spectral gap of the coupling graph. Whole‐brain modelling using QL fits the empirical data significantly better and has a lower model‐derived energy cost than the non‐QL model.
Gustavo Deco, Yonatan Sanz Perl, Natasha Greenstein, Shamil Chandaria, Gregory Scholes, Morten L. Kringelbach   +5 more
wiley   +1 more source

Motor Processes in Children's Mental Rotation [PDF]

, 2009
Previous studies with adult human participants revealed that motor activities can influence mental rotation of body parts and abstract shapes. In this study, we investigated the influence of a rotational hand movement on mental rotation performance from ...
Daum, Moritz M., Frick, A, Frick, Andrea, Frick, A., Mast, F W, Walser, Simone; https://orcid.org/, Mast, F., Daum, Moritz M; https://orcid.org/, Mast, Fred W., Daum, M., Walser, S., Walser, Simone   +11 more
core   +1 more source