Results 141 to 150 of about 67,358 (303)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Mental Stress Follows Mental Rules [PDF]

Journal of Clinical Endocrinology & Metabolism, 1999
openaire   +2 more sources

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Individualistic mentality and economic education

, 2011
The article focuses on economic education broadened by the effects of market mechanism on social system. In economic and social research, the two basic approaches are individualism and collectivism.
Horeháj, Jozef, Kubišová, Ľuboslava
core  

Measuring Enlarged Mentality: Development and Validation of the Enlarged Mentality Scale

Hannah Arendt's concept of enlarged mentality (also referred to as representative thinking) has received much attention from theorists and philosophers, but it has not been a central concept in the empirical political communication literature.
Jones-Jang, S. Mo, Degefe, Elizabeth Demissie, Chung, Myojung, Kim, Nuri   +3 more
core   +1 more source

Contextual extension and validation of the Fo Mentality Scale among Chinese college students. [PDF]

Front Psychol
Chen Q, Xin Z.
europepmc   +1 more source

Mental Handicap and the Mental Health Act [PDF]

Bulletin of the Royal College of Psychiatrists, 1985
openaire   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Rejecting conspiracies doesn't necessarily mean that you're smart: The relationship between conspiracy discrimination and reasoning ability. [PDF]

Br J Soc Psychol
Robson SG, Martire KA, Pearson S, Cosgrove TJ, Jetten J, Faasse K, Hornsey MJ.   +6 more
europepmc   +1 more source