Results 61 to 70 of about 22,311 (267)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Preview of BPM6 Methodology and Analysis of Foreign Direct Investment in 2015 in Croatia

open access: yesActa Economica et Turistica, 2017
Foreign direct investments include equity capital, reinvested earnings and debt relations between ownership-related residents and non-residents. Since 31 October 2014, the Croatian National Bank has started to publish information in the field of ...
Šlogar Helena   +2 more
doaj   +1 more source

GENETIC DETERMINATIONS OF MENTALITY

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2015
Purpose. The article is devoted to clarifying the role of physicality and psycho-physical characteristics of a person as a preconditions of the mentality forming.
L. V. Osadcha
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Legal mentality and causes of corruption in Ukraine

open access: yesНауково-інформаційний вісник Івано-Франківського університету права імені Короля Данила Галицького
Purpose. The purpose of the study is to analyze the legal mentality of Ukrainian society as an important factor influencing the formation and spread of corruption, to identify its root causes, and to develop recommendations for overcoming this phenomenon
Dovhanych V.
doaj   +1 more source

Value-Semantic Blocks in Images of African Poetry (in the Context of Historical and Social Changes) [PDF]

open access: yesУченые записки Института Африки Российской академии наук
The article presents an interdisciplinary study at the intersection of culturology and African studies. The author suggests that the formation and transformation of values and meanings in Africa were influenced by specific facts of the history of sub ...
Kharitonova Elena Vladimirovna
doaj   +1 more source

Mental illness and mental health [PDF]

open access: yesThe Lancet Psychiatry, 2017
Adam M, Chekroud   +2 more
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

“Oydinda Yurgan Odamlar” Qissasidagi Maqollarda “Oila” Konsepti

open access: yesİmgelem
Bu makale son çeyrek asırda ortaya çıkan ve gelişmekte olan kültür dilbilim alanında yazılmıştır. Atasözleri söz konusu dilbilim dalının temel kavramı olan konseptleri analiz etmek için en önemli mazleme sayılır.
Nuriddin Altinbaev, Rajab Abdiyev
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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