Results 11 to 20 of about 19,622 (211)

New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties

open access: yesPharmaceutics, 2023
This study describes the preparation, characterization, and influence of the enantiopure vs. racemic coformer on the physico-chemical properties of a pharmaceutical cocrystal.
Panpan Ma   +17 more
doaj   +1 more source

Improvement of the pharmacological activity of menthol via enzymatic β-anomer-selective glycosylation

open access: yesAMB Express, 2017
Menthol has a considerable cooling effect, but the use range of menthol is limited because of its extremely low solubility in water and inherent flavor.
Ha-Young Choi   +4 more
doaj   +1 more source

Menthol cigarette smoking and obesity in young adult daily smokers in Hawaii

open access: yesPreventive Medicine Reports, 2015
This study investigates 1) the relationship between menthol cigarette smoking and obesity and 2) the association of body mass index with the nicotine metabolite ratio among menthol and non-menthol daily smokers aged 18–35 (n = 175).
Alyssa Marie M. Antonio   +18 more
doaj   +1 more source

Plasma Menthol Glucuronide as a Biomarker for the Behavioral Effects of Menthol and Nicotine in Humans

open access: yesFrontiers in Pharmacology, 2022
This secondary analysis sought to determine if plasma menthol glucuronide (MG) concentrations predict changes in three outcomes, subjective drug effects, urges to smoke, and heart rate, following concurrent inhaled menthol and intravenous nicotine.
Ralitza Gueorguieva   +11 more
doaj   +1 more source

THE CRYSTALLIZATION OF MENTHOL. [PDF]

open access: yesJournal of the American Chemical Society, 1917
n ...
openaire   +2 more sources

Tobacco industry tactics to circumvent and undermine the TPD menthol ban in the UK

open access: yesTobacco Prevention and Cessation, 2020
Background The World Health Organisation recommends banning menthol cigarettes because of menthol’s role in the initiation and continuance of smoking. Across the world, the tobacco industry has attempted to block, stall, limit or circumvent legislation ...
Karin K. Silver, Rosemary Hiscock
doaj   +1 more source

A-type GABA receptor as a central target of TRPM8 agonist menthol. [PDF]

open access: yesPLoS ONE, 2008
Menthol is a widely-used cooling and flavoring agent derived from mint leaves. In the peripheral nervous system, menthol regulates sensory transduction by activating TRPM8 channels residing specifically in primary sensory neurons.
Xiao-Bing Zhang   +7 more
doaj   +1 more source

Engineered Saccharomyces cerevisiae for the De Novo Biosynthesis of (−)-Menthol

open access: yesJournal of Fungi, 2022
Menthol, a high-value commodity monoterpenoid chemical, holds an important market share commercially because of its distinct functions. The menthol on the market mainly originates from plant extraction, which is facing challenges such as the seasonal ...
Xueqin Lv   +7 more
doaj   +1 more source

Ca<sup>2+</sup>-independent cytotoxicity of menthol in the A549 lung cancer cell line. [PDF]

open access: yesCurr Res Toxicol
Menthol evokes cooling sensations by activating the transient receptor potential melastatin 8 (TRPM8) channel, resulting in relaxing, anti-inflammatory, and analgesic effects when administered through inhalation and topical application.
Takahashi K, Ohta T.
europepmc   +2 more sources

Custom mentholation of commercial cigarettes for research purposes

open access: yesToxicology Reports, 2014
In the U.S. menthol remains the sole permitted characterizing cigarette flavor additive in part because efforts to link menthol cigarette use to increased tobacco-related disease risk have been inconclusive. To perform definitive studies, cigarettes that
Ian C. MacGregor   +11 more
doaj   +1 more source

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