Results 31 to 40 of about 65,266 (300)

Protective effects of menthol against sepsis-induced hepatic injury: Role of mediators of hepatic inflammation, apoptosis, and regeneration

open access: yesFrontiers in Pharmacology, 2022
Liver dysfunction in sepsis is a major complication that amplifies multiple organ failure and increases the risk of death. Inflammation and oxidative stress are the main mediators in the pathophysiology of sepsis.
A. Matouk   +9 more
semanticscholar   +1 more source

Tobacco industry tactics to circumvent and undermine the TPD menthol ban in the UK

open access: yesTobacco Prevention and Cessation, 2020
Background The World Health Organisation recommends banning menthol cigarettes because of menthol’s role in the initiation and continuance of smoking. Across the world, the tobacco industry has attempted to block, stall, limit or circumvent legislation ...
Karin K. Silver, Rosemary Hiscock
doaj   +1 more source

A-type GABA receptor as a central target of TRPM8 agonist menthol. [PDF]

open access: yesPLoS ONE, 2008
Menthol is a widely-used cooling and flavoring agent derived from mint leaves. In the peripheral nervous system, menthol regulates sensory transduction by activating TRPM8 channels residing specifically in primary sensory neurons.
Xiao-Bing Zhang   +7 more
doaj   +1 more source

Therapeutic hydrophobic deep eutectic solvents of menthol and fatty acid for enhancing anti-inflammation effects of curcuminoids and curcumin on RAW264.7 murine macrophage cells

open access: yesRSC Advances, 2022
Owing to their water insolubility, low stability, and poor absorption, anti-inflammatory curcuminoids (CUN) are difficult to be extracted and delivered to the action site.
K. Kongpol   +5 more
semanticscholar   +1 more source

In Vitro Consequences of Electronic-Cigarette Flavoring Exposure on the Immature Lung. [PDF]

open access: yes, 2019
Background: The developing lung is uniquely susceptible and may be at increased risk of injury with exposure to e-cigarette constituents. We hypothesize that cellular toxicity and airway and vascular responses with exposure to flavored refill solutions ...
Berkelhamer, Sara   +5 more
core   +2 more sources

Targeting the transcription factor HES1 by L-menthol restores protein phosphatase 6 in keratinocytes in models of psoriasis

open access: yesNature Communications, 2022
Protein Phosphatase 6 down-regulation in keratinocytes is a pivotal event that amplifies the inflammatory circuits in psoriasis, indicating that restoration of protein phosphatase 6 can be a rational strategy for psoriasis treatment.
Zhikai Wang   +14 more
semanticscholar   +1 more source

Use of Menthol Cigarettes, Smoking Frequency, and Nicotine Dependence Among US Youth

open access: yesJAMA Network Open, 2022
Key Points Question Do youth menthol cigarette smokers smoke more frequently and display greater symptoms of nicotine dependence than youth nonmenthol cigarette smokers? Findings In this population-based pooled cohort study including 1492 observations of
E. Leas   +3 more
semanticscholar   +1 more source

Menthol sensory qualities and smoking topography: a review of tobacco industry documents. [PDF]

open access: yes, 2011
ObjectiveTo determine what the tobacco industry knew about the potential effects of menthol on smoking topography-how a person smokes a cigarette.MethodsA snowball strategy was used to systematically search the Legacy Tobacco Documents Library (http ...
McCandless, Phyra M, Yerger, Valerie B
core   +2 more sources

Impact of the European Union’s menthol cigarette ban on smoking cessation outcomes: longitudinal findings from the 2020–2021 ITC Netherlands Surveys

open access: yesTobacco Control, 2022
Introduction To reduce the appeal of tobacco, the European Union (EU) banned menthol as a characterising flavour in cigarettes in May 2020. This pre/post-study evaluated the impact of the menthol ban on smoking cessation outcomes among a representative ...
C. Kyriakos   +8 more
semanticscholar   +1 more source

Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice. [PDF]

open access: yesPLoS ONE, 2015
Addition of menthol to cigarettes may be associated with increased initiation of smoking. The potential mechanisms underlying this association are not known.
Michael A Ha   +7 more
doaj   +1 more source

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