Results 41 to 50 of about 6,199 (251)

Synthetic cathinones related fatalities: an update [PDF]

, 2018
Synthetic cathinones, more commonly known as "bath salts", are synthetic drugs chemically related to cathinone, a psychostimulant found in the khat plant.
Busardò, F. P., Giorgetti, R., Marinelli, E., Pantano, F., Pichini, S., Zaami, S.   +5 more
core   +1 more source

Binge-like mephedrone treatment induces memory impairment concomitant with brain kynurenic acid reduction in mice.

Toxicology and Applied Pharmacology, 2022
While mephedrone (4-methylmethcathinone), a synthetic cathinone derivative, is widely abused by adolescents and young adults, the knowledge about its long-term effects on memory processes is limited.
M. Marszałek-Grabska, I. Zakrocka, B. Budzyńska, S. Marciniak, K. Kaszubska, M. Lemieszek, Sylwia Winiarczyk, J. Kotlinska, W. Rzeski, W. Turski   +9 more
semanticscholar   +1 more source

Mephedrone and chemsex: a case report

Legal Medicine, 2020
The chemsex or slamsex phenomenon has attracted attention worldwide, with concerns also expressed by health professionals for the spread of sexually transmitted diseases. Mephedrone or 4-methylmethcathinone, a substituted cathinone homolog of ephedrine, is one of the most popular substances used as a cheaper alternative to other traditional drugs ...
Anzillotti L., Calo L., Banchini A., Schirripa M. L., Marezza F., Cecchi R.   +5 more
openaire   +3 more sources

A study of in vitro metabolism and cytotoxicity of mephedrone and methoxetamine in human and pig liver models using GC/MS and LC/MS analyses

Open Chemistry, 2020
In the current study, the metabolism of two novel psychoactive substances (NPSs), mephedrone and methoxetamine (MXE), was studied in vitro in pig liver microsomes to determine potential metabolites by liquid chromatography-mass spectrometry (LC-MS ...
Alshamaileh Majed, Hussain Issam, Baron Mark, Croxton Ruth, Vetter Marleen, Gonzalez-Rodriguez Jose   +5 more
doaj   +1 more source

Mephedrone pharmacokinetics after intravenous and oral administration in rats: relation to pharmacodynamics [PDF]

, 2014
Fe d'errates disponible a: http://​dx.​doi.​org/​10.​1007/​s00213-013-3283-6Rationale Mephedrone (4-methylmethcathinone) is a still poorly known drug of abuse, alternative to ecstasy or cocaine.
A Winstock, AJ Dickson, C Csajka, CM Hysek, D. Pubill, DM Wood, DM Wood, E. Escubedo, F Nagai, F Schifano, GC Hadlock, HC Porchet, J Fonsart, J Martínez-Clemente, J. Camarasa, J. Martínez-Clemente, KJ Varner, LB Sheiner, LD Simmler, LK Sørensen, M. Carbó, MD Schechter, MH Baumann, MH Baumann, MR Meyer, NV Cozzi, OI Khreit, P Wilkinson, PD Maskell, PH Barrett, R López-Arnau, R. López-Arnau, SA Hitchcock, T Chu, TM Brunt   +34 more
core   +2 more sources

Alteration of Ethanol Reward by Prior Mephedrone Exposure: The Role of Age and Matrix Metalloproteinase-9 (MMP-9)

International Journal of Molecular Sciences, 2022
Mephedrone, a synthetic cathinone, is widely abused by adolescents and young adults. The aim of this study was to determine: (i) whether prior mephedrone exposure would alter ethanol reward and (ii) whether age and matrix metalloproteinase-9 (MMP-9) are ...
P. Grochecki, I. Smaga, M. Marszałek-Grabska, Malgorzata Lopatynska-Mazurek, Tymoteusz Słowik, E. Gibuła-Tarłowska, E. Kędzierska, J. Listos, M. Filip, J. Kotlinska   +9 more
semanticscholar   +1 more source

Roar of meow-meow (mephedrone) in India

Journal of Mental Health and Human Behaviour, 2015
Recently, a dangerous new designer drug mephedrone has fast gained popularity among the youth and teens of India. Its abuse has soared to mount to an epidemic.
Pooja Yudhishthir Palkar, Anand Ajit Kumthekar   +1 more
doaj   +1 more source

Low levels of chemsex among men who have sex with men, but high levels of risk among men who engage in chemsex: analysis of a cross-sectional online survey across four countries [PDF]

, 2018
Background: This paper establishes the prevalence of chemsex drug use among men who have sex with men (MSM), the extent to which these drugs are used in a sexual context, as well as their associated behaviours and circumstances of use. Methods: Data from
Bourne, Adam, Flowers, Paul, Frankis, Jamie, McDaid, Lisa   +3 more
core   +3 more sources

Deaths of individuals aged 16-24 years in the UK after using mephedrone [PDF]

, 2015
Objective: Mephedrone is a stimulant drug chemically related to amphetamine, with effects similar to those of amphetamine and cocaine. This study aims to analyse fatalities following ingestion of mephedrone in the UK amongst 16-24 year olds in 2009-13 ...
Advisory Council on the Misuse of Drugs (ACMD), Advisory Council on the Misuse of Drugs (ACMD), Carhart-Harris, Corkery, Cosbey, Cozzi, Dargan, De Letter, Dickson, Durham, Dyer, Home Office, James, Kalix, Kalix, López-Arnau, Maskell, Measham, Meltzer, Morris, Newcombe, Schifano, Schifano, Schifano, Schifano, Schifano, Simmler, Torrance, Tsitsika, Winstock, Winstock, Winstock, Wood, Wood, Wood, Wood, Yamamoto   +36 more
core   +1 more source

Excretion of mephedrone and its phase I metabolites in urine after a controlled intranasal administration to healthy human volunteers

Drug Testing and Analysis, 2022
Mephedrone is a stimulant drug structurally related to cathinone. At present, there are no data available on the excretion profile of mephedrone and its metabolites in urine after controlled intranasal administration to human volunteers.
Joanna Czerwinska, M. Parkin, C. George, A. Kicman, P. Dargan, V. Abbate   +5 more
semanticscholar   +1 more source