Results 21 to 30 of about 6,199 (251)

Impact of Mephedrone on Fear Memory in Adolescent Rats: Involvement of Matrix Metalloproteinase-9 (MMP-9) and N-Methyl-D-aspartate (NMDA) Receptor

open access: yesInternational Journal of Molecular Sciences, 2023
Treatment of Post-Traumatic Stress Disorder (PTSD) is complicated by the presence of drug use disorder comorbidity. Here, we examine whether conditioned fear (PTSD model) modifies the rewarding effect of mephedrone and if repeated mephedrone injections ...
P. Grochecki   +9 more
semanticscholar   +1 more source

Cutaneous features at injection sites of intravenous mephedrone.

open access: yesBritish Journal of Dermatology, 2023
We present the cutaneous adverse effects of subcutaneous extravasation of mephedrone resulting in thrombotic vasculopathy and chronic ulcerations. Due to the increasing use of mephedrone, especially among the community of men who have sex with men ...
Manuel Agud de Dios   +4 more
semanticscholar   +1 more source

Mephedrone inhalation causes pneumomediastinum [PDF]

open access: yesBMJ Case Reports, 2014
A 17-year-old male patient presented to A&E with swelling on the right side of his neck, extending to below the clavicle, associated with neck pain and dysphonia. On examination, subcutaneous supraclavicular and chest wall emphysema was noted. Clinical observations and bloods were normal.
Ruth, Graham, Nia, Bowen, Joy, Singh
openaire   +2 more sources

Chemsex drugs: More than ghb, mephedrone and methamphetamine?

open access: yesEuropean Psychiatry, 2021
Introduction The intentional use of drugs before or during sexual intercourse (chemsex), due to its impact on mental health, is a phenomenon of high importance in men who have sex with men.
J. Curto Ramos   +3 more
doaj   +1 more source

Mephedrone induces partial release at human dopamine transporters but full release at human serotonin transporters.

open access: yesNeuropharmacology, 2023
Mephedrone (4-methylmethcathinone) is a cathinone derivative that is recreationally consumed for its energizing and empathogenic effects. The stimulating properties are believed to arise from the ability of mephedrone to interact with the high-affinity ...
F. P. Mayer   +11 more
semanticscholar   +1 more source

Urinary retention secondary to mephedrone [PDF]

open access: yesBMJ Case Reports, 2013
We discuss a case of a 25-year-old man who presented to the acute medical take with a mixed overdose of mephedrone and paracetamol. Sixteen hours after ingestion, he reported that he was unable to micturate. A bladder scan confirmed that he was in urinary retention and he was catheterised.
Nerys, Conway   +3 more
openaire   +2 more sources

Relationship between GABA-Ergic System and the Expression of Mephedrone-Induced Reward in Rats—Behavioral, Chromatographic and In Vivo Imaging Study

open access: yesInternational Journal of Molecular Sciences, 2023
Mephedrone is a psychoactive drug that increases dopamine, serotonin and noradrenaline levels in the central nervous system via interaction with transporters or monoamines. The aim of the presented study was to assess the role of the GABA-ergic system in
Olga Wronikowska-Denysiuk   +9 more
semanticscholar   +1 more source

Psychoactive Substances Taken with Mephedrone and HCV Infection [PDF]

open access: yesJournal of Clinical Medicine, 2021
Background: In recent years, the observed frequency of hospitalization of patients taking mephedrone with other psychoactive substances has increased. There are no data in the literature on the effect of mephedrone use on liver function in patients, including the frequency of HCV infection. We have analysed the impact of taking mephedrone together with
Michal Ordak   +3 more
openaire   +3 more sources

Recent trends in analytical methods to determine new psychoactive substances in hair [PDF]

open access: yes, 2017
New Psychoactive Substances (NPS) belong to several chemical classes, including phenethylamines, piperazines, synthetic cathinones and synthetic cannabinoids.
García Algar, Oscar   +4 more
core   +1 more source

Investigation of Biotransformation Products of p-Methoxymethylamphetamine and Dihydromephedrone in Wastewater by High-Resolution Mass Spectrometry

open access: yesMetabolites, 2021
There is a paucity of information on biotransformation and stability of new psychoactive substances (NPS) in wastewater. Moreover, the fate of NPS and their transformation products (TPs) in wastewater treatment plants is not well understood.
Juliet Kinyua   +6 more
doaj   +1 more source

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