Results 11 to 20 of about 6,199 (251)

Neurotoxicity Induced by Mephedrone: An up-to-date Review [PDF]

open access: yesCurrent Neuropharmacology, 2017
BACKGROUND: Mephedrone is a β-ketoamphetamine belonging to the family of synthetic cathinones, an emerging class of designer drugs known for their hallucinogenic and psychostimulant properties as well as for their abuse potential.
Flaminia Pantano   +2 more
exaly   +7 more sources

Dose and time-dependent selective neurotoxicity induced by mephedrone in mice. [PDF]

open access: yesPLoS ONE, 2014
Mephedrone is a drug of abuse marketed as 'bath salts". There are discrepancies concerning its long-term effects. We have investigated the neurotoxicity of mephedrone in mice following different exposition schedules.
José Martínez-Clemente   +5 more
doaj   +4 more sources

The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties

open access: yesJournal of Neuroinflammation, 2021
Background Synthetic cathinones are a category of psychostimulants belonging to the growing number of designer drugs also known as “Novel Psychoactive Substances” (NPS).
Tetyana P. Buzhdygan   +6 more
doaj   +2 more sources

The Effect of Selected Cathinones on Natural Cell Membranes: Microelectrophoretic Methods [PDF]

open access: yesMolecules
Synthetic cathinones are cathinone analogues that humans have artificially created. The first compounds appeared on the European market in 2005. They belong to a class of drugs called stimulants, classified as new psychoactive substances.
Anna Trynda   +4 more
doaj   +2 more sources

Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers

open access: yesPharmaceuticals, 2020
Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers: R-(+)-mephedrone and S-(−)-mephedrone.
Joanna Czerwinska   +6 more
doaj   +2 more sources

Comparative Untargeted Metabolomics Analysis of the Psychostimulants 3,4-Methylenedioxy-Methamphetamine (MDMA), Amphetamine, and the Novel Psychoactive Substance Mephedrone after Controlled Drug Administration to Humans

open access: yesMetabolites, 2020
Psychoactive stimulants are a popular drug class which are used recreationally. Over the last decade, large numbers of new psychoactive substances (NPS) have entered the drug market and these pose a worldwide problem to human health.
Andrea E. Steuer   +10 more
doaj   +2 more sources

Novel Psychoactive Substances—Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs [PDF]

open access: yesFrontiers in Psychiatry, 2017
A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Zurina Hassan   +8 more
doaj   +3 more sources

Forensic Electrochemistry: The Electroanalytical Sensing of Mephedrone Metabolites

open access: yesACS Omega, 2019
The constant and persistent synthesis and abuse of new psychoactive substances have sparked the requirement for rapid, on-site, sensitive analytical protocols for their sensing and quantification.
Hadil M. Elbardisy   +8 more
doaj   +2 more sources

Characteristics of methamphetamine-related deaths in the United Kingdom, 1997-2024. [PDF]

open access: yesAddiction
Abstract Background and aims People who use methamphetamine have a standardised mortality ratio 6.8 times greater than the general population, with several countries reporting concerning increases in methamphetamine‐related mortality over the past decade.
Roberts E, McKetin R, Copeland C.
europepmc   +2 more sources

A Sexual Affiliation Network of Men Who Have Sex With Men Practicing Risk Sexual Behaviors and Chemsex: A Two-Mode Approach. [PDF]

open access: yesPublic Health Nurs
ABSTRACT Background Dating apps for men who have sex with men (MSM) have facilitated unprotected sexual encounters and practices. In addition, drug use during such encounters is widespread among MSM. Traditionally, these populations have been studied in order to relate these facts to their socioeconomic characteristics and not from the perspective of ...
Marqués-Sánchez P   +5 more
europepmc   +2 more sources

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