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Meprobamate Overdosage

Human Toxicology, 1985
Meprobamate is a non-barbiturate hypnotic/tranquillizer, first used clinically in 1955. One preparation (Tenavoid; Edwin Burgess) contains meprobamate and bendrofluazide and is prescribed for pre-menstrual tension. In adults therapeutic plasma meprobamate concentrations range up to 10 mg/l and unwanted side-effects occur at greater ...
J, Dennison, J N, Edwards, G N, Volans
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Addiction to Meprobamate

New England Journal of Medicine, 1957
THE use of meprobamate§ has become widespread in a variety of disturbances of emotional origin. Physicians are under much demand for this drug from patients whose information is obtained largely from the lay press, radio and television. Hence, they are now faced with the situation in which huge quantities are consumed and yet the possible adverse ...
J A, EWING, R E, FULLILOVE
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Dissociation of Learning and Meprobamate

Psychological Reports, 1967
The study was designed to determine whether rats trained in an avoidance conditioning situation while drugged (meprobamate) would demonstrate a decrement in performance when tested without the drug. Also, would Ss trained without the drug exhibit a decrement when tested on the drug.
S S, Barnhart, D W, Abbott
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Hydrolysis and determination of meprobamate

Pharmaceutisch Weekblad Scientific Edition, 1983
Most pharmacopoeial methods for meprobamate are based on acid hydrolysis, followed by determination of the ammonia formed. In order to find optimum conditions the hydrolysis was studied with the aid of TLC. Various types and concentrations of acid were tested.
S M, Dreijer-van der Glas, H A, Dingjan
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ADVERSE REACTIONS TO MEPROBAMATE

Journal of the American Medical Association, 1956
• Adverse reactions seen after the administration of the tranquilizing drug meprobamate included cutaneous, muscular, gastrointestinal, and paradoxical cerebral effects. The cutaneous effects, seen in five cases, were chiefly purpuric and accompanied by intense itching; one 400-mg.
H T, FRIEDMAN, W L, MARMELZAT
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Acute Meprobamate Poisoning

New England Journal of Medicine, 1958
MEPROBAMATE, or 2-methyl-2-n-propyl-1,3-propanediol dicarbamate, is a tranquilizing drug that has become widely used in the short time since its synthesis in 1950.1 It has been proved to be of particular value in anxiety and tension states and numerous related conditions.2 It has also been used to good advantage in various types of skeletal-muscle ...
L W, POWELL, G T, MANN, S, KAYE
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Meprobamate Addiction

New England Journal of Medicine, 1958
R C, MOHR, B T, MEAD
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