Results 121 to 130 of about 224,221 (263)

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Promoting effect of small molecules in cardiomyogenic and neurogenic differentiation of rat bone marrow-derived mesenchymal stem cells

Drug Design, Development and Therapy, 2015
Ramin Khanabdali,1 Anbarieh Saadat,1 Maizatul Fazilah,1 Khairul Fidaa’ Khairul Bazli,1 Rida-e-Maria Qazi,2 Ramla Sana Khalid,2 Durriyyah Sharifah Hasan Adli,1 Soheil Zorofchian Moghadamtousi,1 Nadia Naeem,2 Irfan Khan,2 Asmat Salim,2 ShamsulAzlin ...
Khanabdali R, Saadat A, Fazilah M, Bazli KFK, Qazi RM, Khalid RS, Hasan Adli DS, Moghadamtousi SZ, Naeem N, Khan I, Salim A, Shamsuddin SAA, Mohan G   +12 more
doaj  

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source

Staufen purification: challenges and opportunities. Protocols and troubleshooting. [PDF]

MethodsX
Shakoor H, Tripepi A.
europepmc   +1 more source

Semicrystalline Polymacrolactone Networks via Disulfide Chemistry: Synthesis, Cross-Linking, and Chemical Degradation Pathways. [PDF]

Polym Sci Technol
Ferrentino N, Russo S, Di Giacomo F, Santulli F, Sorrentino A, Mazzeo M, Pappalardo D.   +6 more
europepmc   +1 more source

Differences Between a Monoclonal Anti-NC1 Antibody (12D) That Selectively Stains Injured Kidneys and Other Anti-NC1 Antibodies. [PDF]

Cureus
Yokoyama T, Tabuchi Y, Hattori S.
europepmc   +1 more source

Streamlined spectroscopic assay for besifloxacin: A one-pot approach evaluating drugs in eye drops and aqueous humor samples based on fluorescent isoindole generation. Comprehensive evaluation of whiteness, and blueness. [PDF]

Sci Rep
Abu-Hassan AA.
europepmc   +1 more source

Protocol for detecting protein S-glutathionylation in Arabidopsis thaliana under oxidative stress using a non-transgenic chemical toolkit. [PDF]

STAR Protoc
Zhao S, Chen X, Wang W.
europepmc   +1 more source

Phosphonate- and Phosphonic Acid-Functionalized Polycyclooctenes Enabling High Ionic Conductivity and Intrinsic Flame Retardancy in Solid-State Lithium-Ion Batteries. [PDF]

ACS Omega
Misenan MSM, Gündoğdu AI, Rahim M, Figen AK, Eren T.   +4 more
europepmc   +1 more source