Results 41 to 50 of about 2,340 (236)

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

open access: yesAdvanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai   +16 more
wiley   +1 more source

The ORCA‐TWIN qCMOS Experiment I. Science Case and Commissioning at Calar Alto Observatory

open access: yesAstronomische Nachrichten, EarlyView.
ABSTRACT We describe a pilot study to explore a new generation of fast and low noise CMOS image sensors for time domain astronomy, using two remote telescopes with a baseline of 1635 km. The experiment involves direct imaging with novel qCMOS image sensor technology that combines fast readout with sub‐electron readout noise.
Martin M. Roth   +20 more
wiley   +1 more source

Origins of Mercury’s Big Heart of Iron: Exploring Pathways to Form High Core Mass Fraction Planets via N-body Simulations

open access: yesThe Astrophysical Journal
Mercury’s core mass fraction (CMF) is 0.7, more than double that of the other rocky planets in the solar system, which have CMFs of 0.3 or lower. The origin of Mercury’s large, iron-rich core remains unknown. Adding to this mystery, an elusive population
Haniyeh Tajer   +5 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

open access: yesBMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang   +6 more
wiley   +1 more source

Temperature-related Variations of 1064 nm Surface Reflectance on Mercury: Implications for Space Weathering

open access: yesThe Planetary Science Journal
It has been predicted that high equatorial temperatures on Mercury could promote thermal annealing by Ostwald ripening, where nanophase metal particles (a product of space weathering) coalesce and grow into larger, microphase particles, resulting in ...
Ariel N. Deutsch   +9 more
doaj   +1 more source

DETERMINATION OF COORDINATES OF THE BASIC POINTS OF THE ILLUMINATED PART OF THE SPHERICAL PLANET'S VISIBLE DISC

open access: yesOdessa Astronomical Publications, 2017
The formulae for determination of planetocentric coordinates of the basic points of an illuminated part of the visible disc of a spherical planet in projection onto the plane of the sky are derived. The formulae are deduced from general expressions using
V. V. Mikhalchuk
doaj   +1 more source

Making the Solar System

open access: yesThe Astrophysical Journal, 2023
We model the early stages of planet formation in the solar system, including continual planetesimal formation, and planetesimal and pebble accretion onto planetary embryos in an evolving disk driven by a disk wind.
John Chambers
doaj   +1 more source

Barriers to the Adoption of Circular Economy Business Models in the Indian Textile Industry

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The Indian textile industry has significant negative impacts on the environment. This industry needs to adopt a circular economy approach to become more sustainable; however, progress on this has been limited. In this study, we report on the barriers to adoption of Circular Economy Business Models (CEBMs) in the Indian textile industry.
Himanshu Chandra   +2 more
wiley   +1 more source

Revisiting Electronic and Nuclear Sputtering from Ions at Mercury Using Linear Cascade Theory

open access: yesThe Planetary Science Journal
This study revisits calculations using linear cascade theory (LCT) to estimate the relative importance of the ion-induced collisional sputtering yield (also referred to as knock-on, nuclear, or kinetic sputtering) and the ion-induced electronic ...
Orenthal J. Tucker   +5 more
doaj   +1 more source

Data‐Driven Pathways to Circular E‐Waste Management

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT As the volume and complexity of electronic waste grow worldwide, regional and subnational systems are increasingly tasked with managing the environmental, economic, and social challenges of circular resource recovery. This paper focuses on Canada's e‐waste sector to examine how circular economy (ce) principles can be integrated into regional ...
Saidia Ali   +3 more
wiley   +1 more source

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