Results 91 to 100 of about 116,668 (290)

Acquiring foreign firms far away might be hazardous to your share price: evidence from Germany [PDF]

open access: yes, 2007
This paper examines shareholder wealth effects of cross-border acquisitions. In a sample of 155 large acquisitions by German corporations from 1985–2006 international transactions in total do not lead to significant announcement returns.
Grote, Michael H., Rücker, Fabian
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Mergers and Acquisitions in Europe [PDF]

open access: yes
This paper provides a comprehensive overview of the European takeover market.We characterize the main features of the domestic and cross-border corporate takeovers involving European companies in the period 1993-2001.We provide detailed and comparable ...
Martynova, M., Renneboog, L.D.R.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

EMPIRICAL EVIDENCE ON THE MOTIVES FOR MERGERS AND ACQUISITIONS IN EIGHT FOOD INDUSTRIES [PDF]

open access: yes
This paper investigates the motives for mergers and acquisitions in eight U.S. food products industries from1977-92. Results show that acquired plants were highly productive before mergers and realized an increase in productivity growth in the post ...
Nguyen, Sang V., Ollinger, Michael
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Mergers and acquisitions: does performance depend on managerial ability? [PDF]

open access: yesJ Innov Entrep, 2023
Suryaningrum DH   +3 more
europepmc   +1 more source

Betcha can’t acquire just one: merger programs and compensation [PDF]

open access: yes
This paper examines the evolution of merger programs, that is, repeated acquisitions by the same firm. Most acquisitions are made by firms with merger programs.
Richard J. Rosen
core  

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