Results 171 to 180 of about 207,836 (317)

A network-based model of Aspergillus fumigatus elucidates regulators of development and defensive natural products of an opportunistic pathogen. [PDF]

Nucleic Acids Res
Carriel CC, Halberg-Spencer SA, Kotvanova M, Pyne S, Park SC, Seo HW, Schmidt A, Calise DG, Ané JM, Keller NP, Roy S.   +10 more
europepmc   +1 more source

Variant Prioritization by Pedigree‐Based Haplotyping

Genetic Epidemiology, Volume 50, Issue 3, April 2026.
ABSTRACT Whole genome sequence (WGS) data provides opportunities for comprehensive evaluation of variants that may influence complex traits. However, prioritizing the large number of variants, particularly those in non‐coding regions, is a challenge.
Rafael A. Nafikov, Harkirat K. Sohi, Alejandro Q. Nato Jr., Andrea R. Horimoto, Tyler R. C. Day, Thomas D. Bird, Anita L. DeStefano, Elizabeth E. Blue, Ellen M. Wijsman   +8 more
wiley   +1 more source

Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype. [PDF]

PLoS One
Ning X, Nguyễn TTT, Morinaga T, Tada Y, Shimada H, Hiroshima K, Yamaguchi N, Tagawa M.   +7 more
europepmc   +1 more source

Mapping Evidence on Care Interventions for People Living With Motor Neurone Disease: A Protocol for a Living Evidence and Gap Map

Clinical and Public Health Guidelines, Volume 3, Issue 2, April 2026.
ABSTRACT Objective To map the available evidence informing the care and management of people living with motor neurone disease (MND), including evidence pertaining to carers, asymptomatic genetic carriers, family, friends and healthcare professionals caring for people with MND.
Danielle Pollock, Cindy Stern, Melissa Bond, Timothy Hugh Barker, Sabira Hasanoff, Grace Holland, Ines Semendric, Anna Fragkoudi, Nipun Shrestha, Sebastian Cole Facchin‐Young, Abigail Molly Day‐Sharman, Lemma Negesa Bulto, Lara Stollery, Sitasma Sharma, Camille Schubert, Lynne Giles, Jay Beasley‐Hall, Tracy Merlin, Julie Labra, Steve Vucic, Taryn Hunt, Zachary Munn   +21 more
wiley   +1 more source

Transient proliferation by reversible YAP and mitogen control of the cyclin D1/p27 ratio. [PDF]

Commun Biol
Ferrick KR, Upadhya SW, Fan Y, Ratnayeke N, Teruel MN, Meyer T.   +5 more
europepmc   +1 more source

Mitochondrial Adaptations in Skeletal Muscle Following Incretin‐Based Therapies: In Vitro

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Incretin‐based therapies such as glucagon‐like peptide‐1 receptor agonists (GLP‐1Ras), dual GLP‐1/GIP agonists and amylin analogues have demonstrated significant weight loss benefits. However, their impact on skeletal muscle mitochondrial function, particularly under metabolic stress, remains unclear. This study aimed to investigate
Victoria Old, Melanie Davies, Matthew Denniff, Pratik Choudhary, Nicholas Eastley, Robert U. Ashford, Emma Watson   +6 more
wiley   +1 more source

Therapeutic Potential of hucMSC-EVs in Diabetic Kidney Disease via Regulating the miR-146b-5p/Merlin/YAP Axis. [PDF]

Stem Cells Int
Li B, Wang Q, Shi L, Liu Q, Qian H, Yu L, Ji C.   +6 more
europepmc   +1 more source

Inclusion by design: A mixed‐methods feasibility study on backward design for inclusive education

Review of Education, Volume 14, Issue 1, April 2026.
Abstract Teachers worldwide are required to plan for student diversity and create inclusive learning environments, yet existing curriculum planning models often lack explicit guidance for inclusive education. This study examined the feasibility of Inclusion by Design (IbD), a backward planning framework developed to support proactive, inclusive lesson ...
Tom Porta, Abu Nawas
wiley   +1 more source

Schwannomatosis tumor modeling: progress and prospects for translational research. [PDF]

J Biol Eng
Madison MS, Xu H, Gonzalez-Vargas Y, Yonk MG, Thompson CM, Haney H, Babbitt D, Du Y, Hirbe AC, Boulis NM, Bai RY, Lei K.   +11 more
europepmc   +1 more source

Bridging the gap: Co‐produced neurodiversity‐affirming resources for undiagnosed children aged 7–11: Insights from children, families and stakeholders

Journal of Research in Special Educational Needs, Volume 26, Issue 2, April 2026.
Abstract This qualitative study investigated the acceptability and suitability of neurodiversity‐affirming psychoeducational resources for children aged 7–11 years without formal autism or attention deficit hyperactivity disorder (ADHD) diagnoses. Using a reflexive thematic analysis of semi‐structured interviews with 24 families and written feedback ...
E. Shore, L. Powell
wiley   +1 more source