Results 31 to 40 of about 207,836 (317)

Merlin is a negative regulator of human melanoma growth.

PLoS ONE, 2012
Merlin is encoded by the neurofibromatosis type 2 (NF2) gene and is a member of the Band 4.1 protein family. This protein acts as a linker that connects cell surface proteins to the actin cytoskeleton.
Lucas B Murray, Ying-Ka Ingar Lau, Qin Yu   +2 more
doaj   +1 more source

Distribution of Merlin in eukaryotes and first report of DNA transposons in kinetoplastid protists.

PLoS ONE, 2021
DNA transposons are defined as repeated DNA sequences that can move within the host genome through the action of transposases. The transposon superfamily Merlin was originally found mainly in animal genomes. Here, we describe a global distribution of the
Ana Luisa Kalb Lopes, Eva Kriegová, Julius Lukeš, Marco Aurélio Krieger, Adriana Ludwig   +4 more
doaj   +1 more source

On the design of an energy-efficient low-latency integrated protocol for distributed mobile sensor networks [PDF]

, 2004
Self organizing, wireless sensors networks are an emergent and challenging technology that is attracting large attention in the sensing and monitoring community.
A.G. Ruzzelli, L. Evers, L. F. W. Van Hoesel, P. J. M. Havinga, S. Dulman, Self Organizing   +5 more
core   +3 more sources

Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma

Cancer Research, 2021
The endogenous retrovirus HERV-K activates oncogenic signaling pathways and promotes proliferation of Merlin-deficient schwannomas and meningiomas, which can be targeted with antiretroviral drugs and TEAD inhibitors.
E. Maze, Bora Agit, S. Reeves, D. Hilton, D. Parkinson, L. Laraba, E. Ercolano, K. Kurian, C. Hanemann, Robert D. Belshaw, S. Ammoun   +10 more
semanticscholar   +1 more source

Merlin status regulates p75NTR expression and apoptotic signaling in Schwann cells following nerve injury

Neurobiology of Disease, 2015
After nerve injury, Schwann cells (SCs) dedifferentiate, proliferate, and support axon regrowth. If axons fail to regenerate, denervated SCs eventually undergo apoptosis due, in part, to increased expression of the low-affinity neurotrophin receptor ...
Iram Ahmad, Augusta Fernando, Richard Gurgel, J. Jason Clark, Linjing Xu, Marlan R. Hansen   +5 more
doaj   +1 more source

FIRST-based survey of Compact Steep Spectrum sources, II. MERLIN and VLA observations of Medium-sized Symmetric Objects [PDF]

, 2004
A new sample of candidate Compact Steep Spectrum (CSS) sources that are much weaker than the CSS source prototypes has been selected from the VLA FIRST catalogue. MERLIN `snapshot' observations of the sources at 5 GHz indicate that six of them have an FR
A. Marecki, Alexander, Arshakian, Augusto, Becker, Bennett, Best, Browne, Cordey, De Breuck, Douglas, Fanaroff, Fanti, Fanti, Fanti, Feretti, Ghisellini, Giovannini, Goldshmidt, Hatziminaoglou, Jamrozy, Janiuk, Kaiser, Komissarov, Kunert, Lara, Liu, Lonsdale, M. Kunert-Bajraszewska, Machalski, Machalski, Murgia, Oshlack, Owsianik, Owsianik, P. Thomasson, Patnaik, Peacock, Polatidis, R. E. Spencer, Readhead, Reynolds, Richstone, Röttgering, Saikia, Saikia, Siemiginowska, Siemiginowska, Slee, Snellen, Snellen, Spencer, Thomasson, Tschager, Vigotti, White, Wiita, Wilkinson, Woo   +58 more
core   +2 more sources

Systematic assessment of template-based genome-scale metabolic models created with the BiGG Integration Tool

Journal of Integrative Bioinformatics, 2022
Genome-scale metabolic models (GEMs) are essential tools for in silico phenotype prediction and strain optimisation. The most straightforward GEMs reconstruction approach uses published models as templates to generate the initial draft, requiring further
Oliveira Alexandre, Cunha Emanuel, Cruz Fernando, Capela João, Sequeira João C., Sampaio Marta, Sampaio Cláudia, Dias Oscar   +7 more
doaj   +1 more source

Merlin-Arthur with efficient quantum Merlin and quantum supremacy for the second level of the Fourier hierarchy [PDF]

, 2018
We introduce a simple sub-universal quantum computing model, which we call the Hadamard-classical circuit with one-qubit (HC1Q) model. It consists of a classical reversible circuit sandwiched by two layers of Hadamard gates, and therefore it is in the ...
Morimae, Tomoyuki, Nishimura, Harumichi, Takeuchi, Yuki   +2 more
core   +2 more sources

Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2

Molecular Therapy: Methods & Clinical Development, 2022
Loss of function of the neurofibromatosis type 2 (NF2) tumor suppressor gene leads to the formation of schwannomas, meningiomas, and ependymomas, comprising ∼50% of all sporadic cases of primary nervous system tumors.
Shilpa Prabhakar, Roberta L. Beauchamp, Pike See Cheah, Akiko Yoshinaga, Edwina Abou Haidar, Sevda Lule, Gayathri Mani, Katia Maalouf, Anat Stemmer-Rachamimov, David H. Jung, D. Bradley Welling, Marco Giovannini, Scott R. Plotkin, Casey A. Maguire, Vijaya Ramesh, Xandra O. Breakefield   +15 more
doaj   +1 more source

Los Baladros de Burgos (1498) y Sevilla (1535) frente a frente: su idiosincrasia y la de su modelo

Revista de Filología Española, 2022
El artículo confronta las dos versiones impresas de Merlin —el Baladro del sabio Merlín con sus profecías impreso por Juan de Burgos (Burgos, 1498) y el “Baladro” publicado como primer libro de la Demanda del Sancto Grial con los maravillosos fechos de ...
Paloma Gracia
doaj   +1 more source