Results 41 to 50 of about 207,836 (317)

Stability of the tumor suppressor merlin depends on its ability to bind paxillin LD3 and associate with β1 integrin and actin at the plasma membrane

Biology Open, 2012
Summary The NF2 gene encodes a tumor suppressor protein known as merlin or schwannomin whose loss of function causes Neurofibromatosis Type 2 (NF2). NF2 is characterized by the development of benign tumors, predominantly schwannomas, in the peripheral ...
Maria Elisa Manetti, Sandra Geden, Marga Bott, Nicklaus Sparrow, Stephen Lambert, Cristina Fernandez-Valle   +5 more
doaj   +1 more source

Impact of sequence variation in the ul128 locus on production of human cytomegalovirus in fibroblast and epithelial cells [PDF]

, 2013
The human cytomegalovirus (HCMV) virion envelope contains a complex consisting of glycoproteins gH and gL plus proteins encoded by the UL128 locus (UL128L): pUL128, pUL130, and pUL131A.
A. J. Davison, Adler, Adler, Akter, Baldanti, Borst, Boyle, Britt, Bronzini, Brunak, Cha, Chan, Chowdary, Compton, Compton, Cunningham, D. J. Dargan, Dargan, Davison, Desmet, Dogan, Dolan, Erice, Feire, Fouts, G. S. Wilkie, Genini, Gerna, Gerna, Grazia Revello, Hahn, Hahn, Haspot, I. Murrell, Irmiere, Isaacson, Isaacson, Jiang, Kari, Kelley, Kinzler, Lilleri, Lopper, Macagno, Magri, Matrosovich, Mocarski, Murphy, O'Connor, P. Tomasec, Paredes, Paterson, Prichard, R. J. Stanton, Rasmussen, Reese, Revello, Ryckman, Ryckman, Ryckman, Saccoccio, Schleiss, Schuessler, Schuessler, Schuessler, Scrivano, Sinclair, Sinzger, Sinzger, Sinzger, Sinzger, Smith, Soroceanu, Stanton, Stanton, Stanton, Stanton, Straschewski, Sun, Talbot, Vanarsdall, Vanarsdall, Wang, Wang, Wang, Warming, Wille, Yu   +87 more
core   +2 more sources

The Neurofibromatosis 2 Tumor Suppressor Gene Product, Merlin, Regulates Human Meningioma Cell Growth by Signaling through YAP

Neoplasia: An International Journal for Oncology Research, 2008
Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder characterized by the occurrence of schwannomas and meningiomas. Several studies have examined the ability of the NF2 gene product, merlin, to function as a tumor suppressor in diverse cell ...
Katherine Striedinger, Scott R. VandenBerg, Gilson S. Baia, Michael W. McDermott, David H. Gutmann, Anita Lal   +5 more
doaj   +1 more source

A usability study in patients with stroke using MERLIN, a robotic system based on serious games for upper limb rehabilitation in the home setting

Journal of NeuroEngineering and Rehabilitation, 2020
Background Neuroscience and neurotechnology are transforming stroke rehabilitation. Robotic devices, in addition to telerehabilitation, are increasingly being used to train the upper limbs after stroke, and their use at home allows us to extend ...
Silvia Guillén-Climent, Ainara Garzo, María Nieves Muñoz-Alcaraz, P. Casado-Adam, Javier Arcas-Ruiz-Ruano, Manuela Mejías-Ruiz, F. Mayordomo-Riera   +6 more
semanticscholar   +1 more source

Merlin/NF2-Lin28B-let-7 Is a Tumor-Suppressive Pathway that Is Cell-Density Dependent and Hippo Independent

Cell Reports, 2016
Contact inhibition of proliferation is critical for tissue organization, and its dysregulation contributes to tumorigenesis. Merlin/NF2 is a tumor suppressor that governs contact inhibition. Although Merlin/NF2 inhibits YAP1 and TAZ, which are paralogous
Hiroki Hikasa, Yoshitaka Sekido, Akira Suzuki   +2 more
doaj   +1 more source

Medium Energy Electron Flux in Earth's Outer Radiation Belt (MERLIN): A Machine Learning Model

Space Weather, 2020
The radiation belts of the Earth, filled with energetic electrons, comprise complex and dynamic systems that pose a significant threat to satellite operation.
A. Smirnov, Max Berrendorf, Yuri Shprits, E. Kronberg, H. Allison, N. Aseev, I. Zhelavskaya, Steven K. Morley, Geoffrey D. Reeves, Matthew R. Carver, F. Effenberger   +10 more
semanticscholar   +1 more source

Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene

BMC Evolutionary Biology, 2005
Background Merlin, the product of the Neurofibromatosis type 2 (NF2) tumor suppressor gene, belongs to the ezrin-radixin-moesin (ERM) subgroup of the protein 4.1 superfamily, which links cell surface glycoproteins to the actin cytoskeleton.
Omelyanchuk Leonid V, Chang Long-Sheng, Akhmametyeva Elena M, Blinov Alexander, Golovnina Kseniya   +4 more
doaj   +1 more source

The e-MERGE Survey (e-MERLIN Galaxy Evolution Survey): overview and survey description [PDF]

Monthly notices of the Royal Astronomical Society, 2020
We present an overview and description of the e-MERGE Survey (e-MERLIN Galaxy Evolution Survey) Data Release 1 (DR1), a large program of high-resolution 1.5-GHz radio observations of the GOODS-N field comprising ∼140 h of observations with enhanced ...
T. Muxlow, Alasdair Thomson, Alasdair Thomson, J. Radcliffe, J. Radcliffe, N. Wrigley, R. Beswick, I. Smail, I. McHardy, Simon Garrington, R. Ivison, R. Ivison, M. Jarvis, M. Jarvis, I. Prandoni, M. Bondi, D. Guidetti, M. Argo, D. Bacon, P. Best, A. Biggs, Scott C. Chapman, K. Coppin, H. Chen, H. Chen, H. Chen, T. Garratt, M. Garrett, M. Garrett, E. Ibar, J. Kneib, J. Kneib, K. Knudsen, L. Koopmans, L. Morabito, E. J. Murphy, A. Njeri, C. Pearson, M. Pérez-Torres, A. Richards, H. Röttgering, M. Sargent, S. Serjeant, Chris Simpson, J. Simpson, A. M. Swinbank, E. Varenius, E. Varenius, T. Venturi   +48 more
semanticscholar   +1 more source

p21-Activated kinases are required for transformation in a cell-based model of neurofibromatosis type 2. [PDF]

PLoS ONE, 2010
NF2 is an autosomal dominant disease characterized by development of bilateral vestibular schwannomas and other benign tumors in central nervous system.
Hoi Yee Chow, Dina Stepanova, Jennifer Koch, Jonathan Chernoff   +3 more
doaj   +1 more source

Merlin: A Language for Provisioning Network Resources [PDF]

, 2014
This paper presents Merlin, a new framework for managing resources in software-defined networks. With Merlin, administrators express high-level policies using programs in a declarative language.
Emin Gün, I Fern, O Pedone, Parisa Jalili Mar, Robert Kleinberg, Robert Soulé, Shrutarshi Basu, Sirer Nate Foster   +7 more
core   +5 more sources