Results 111 to 120 of about 444,796 (301)

Evaluation of candidate vaccine approaches for MERS-CoV [PDF]

Nature Communications, 2015
AbstractThe emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) as a cause of severe respiratory disease highlights the need for effective approaches to CoV vaccine development. Efforts focused solely on the receptor-binding domain (RBD) of the viral Spike (S) glycoprotein may not optimize neutralizing antibody (NAb) responses. Here we
Wang, L, Shi, W, Joyce, MG, Modjarrad, K, Zhang, Y, Leung, K, Lees, CR, Zhou, T, Yassine, HM, Kanekiyo, M, Yang, Z-Y, Chen, X, Becker, MM, Freeman, M, Vogel, L, Johnson, JC, Olinger, G, Todd, JP, Bagci, U, Solomon, J, Mollura, DJ, Hensley, L, Jahrling, P, Denison, MR, Rao, SS, Subbarao, K, Kwong, PD, Mascola, JR, Kong, W-P, Graham, BS   +29 more
openaire   +4 more sources

A chimeric MERS-CoV virus-like particle vaccine protects mice against MERS-CoV challenge

Virology Journal, 2022
Abstract Background Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory disease in humans, with a case fatality rate of approximately 35%, thus posing a considerable threat to public health.
Jung-Eun Park, Ji-Hee Kim, Jae-Yeon Park, Sung-Hoon Jun, Hyun-Jin Shin   +4 more
openaire   +3 more sources

Rapid and Sensitive Detection of RNA Viruses through Imaging of Marker Molecules Derived from Designed Circular DNA Probes

Small Methods, EarlyView.
This study presents a rapid and sensitive virus detection method that employs imaging of virus‐specific DNA markers. Utilizing specially designed single‐stranded circular DNA probes, this method captures RNA fragments from RNase‐digested viral genomes during the reverse transcriptase‐based reaction, resulting in double‐stranded markers that are ...
Yoon‐ha Jang, Taesoo Kim, Su‐jin Hong, Se‐yeon Kim, Hyeseung Hwang, Siwon Kim, Su‐a Kang, Nabin Won, Dogeun Kim, Min Jae Kim, Yong Pil Chong, Seongsoo Jang, Kyubong Jo, Kwang‐il Lim   +13 more
wiley   +1 more source

Comparison of the COVID-2019 (SARS-CoV-2) pathogenesis with SARS-CoV and MERS-CoV infections

Future Virology, 2020
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first identified in several patients who traveled to Wuhan or went to a seafood wholesale market in Wuhan.
M. Fani, A. Teimoori, S. Ghafari
semanticscholar   +1 more source

MERS-COV [PDF]

International Journal of Infectious Diseases, 2014
Beuy Joob, Viroj Wiwanitkit
openaire   +5 more sources

Detection of the Middle East Respiratory Syndrome Coronavirus Genome in an Air Sample Originating from a Camel Barn Owned by an Infected Patient

mBio, 2014
Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel betacoronavirus that has been circulating in the Arabian Peninsula since 2012 and causing severe respiratory infections in humans.
Esam I. Azhar, Anwar M. Hashem, Sherif A. El-Kafrawy, Sayed Sartaj Sohrab, Asad S. Aburizaiza, Suha A. Farraj, Ahmed M. Hassan, Muneera S. Al-Saeed, Ghazi A. Jamjoom, Tariq A. Madani   +9 more
doaj   +1 more source

A fusion peptide in the spike protein of MERS coronavirus [PDF]

, 2019
Coronaviruses represent current and emerging threats for many species, including humans. Middle East respiratory syndrome-related coronavirus (MERS-CoV) is responsible for sporadic infections in mostly Middle Eastern countries, with occasional transfer ...
Benjamin W. Neuman, Earp, Entedar A. J. Alsaadi, Hu, Ian M. Jones   +4 more
core   +1 more source

Medical countermeasures during public health emergencies—Does information sharing among health system coalition help?

Decision Sciences, EarlyView.
Abstract Challenged by constrained healthcare resources, hospitals encounter barriers to accommodating patient demand during public health emergencies. Building on a comprehensive literature review of information and knowledge exchange in healthcare, disaster management, and humanitarian operations management, this study explores the influence of ...
Sukrit Pal, Anand Nair
wiley   +1 more source

Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors

Nature Structural & Molecular Biology, 2019
The Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe and often lethal respiratory illness in humans, and no vaccines or specific treatments are available. Infections are initiated via binding of the MERS-CoV spike (S) glycoprotein to
Young-Jun Park, A. Walls, Zhaoqian Wang, M. Sauer, Wentao Li, M. A. Tortorici, B. Bosch, F. DiMaio, D. Veesler   +8 more
semanticscholar   +1 more source

To what extent are Arab pilgrims to Makkah aware of the middle east respiratory syndrome coronavirus and the precautions against it?

Journal of Family and Community Medicine, 2017
BACKGROUND: Approximately, 80% of the many cases of the Middle East respiratory syndrome coronavirus (MERS-CoV) confirmed worldwide were diagnosed in the Kingdom of Saudi Arabia (KSA).
Meshaal S Alotaibi, Abdulaziz M Alsubaie, Khaled A Almohaimede, Turki A Alotaibi, Omar A Alharbi, Abdulrahman F Aljadoa, Abdulaziz H Alhamad, Mazin Barry   +7 more
doaj   +1 more source