Results 91 to 100 of about 252,954 (227)
MERS-CoV: Bridging the Knowledge Gaps
Oman Medical Journal, 2014 Since its emergence in September 2012 and as of 30 April 2014, there have been 424 cases of the Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) reported to public health authorities worldwide (15 countries). This tally includes 95 healthcare workers (22%) and 131 deaths (mortality rate of 31%).1 To date, only two laboratory confirmed cases have
Abdullah Balkhair +4 more
openaire +3 more sources
ProTides for Antiviral Activity Beyond Liver Cells
Chemistry – A European Journal, Volume 32, Issue 21, 1 June 2026.A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel +5 more
wiley +1 more source
Broadly Protective Antibody‐Like Vaccines Against Highly Pathogenic Coronaviruses
Journal of Medical Virology, Volume 98, Issue 6, June 2026.ABSTRACT SARS‐CoV‐2 and MERS‐CoV are highly pathogenic and contagious coronaviruses. Despite intensive vaccination, SARS‐CoV‐2 continues to spread, and no FDA‐approved vaccines exist for MERS‐CoV; thus, more effective and safer vaccine options are needed. The receptor‐binding domain (RBD) of coronaviruses is a primary target of neutralizing antibodies (
Assala Helal +20 more
wiley +1 more source
MERS-CoV infection fails to activate the stress response pathway.
, 2016 (A) Immune fluorescence images of mock-treated an MERS-CoV infected Vero cells. Cells were infected with an MOI of 1 and fixed using 3% paraformaldehyde in PBS at 10h or 24h post infection.
Isabel Sola (218107) +10 more
core +1 more source
, 2023 Prospective cohort study to investigate the potential exposure to the Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) following Hajj pilgrims is still very limited.
Boon-Teong Teoh (409368) +17 more
core +1 more source
Journal of Infection and Public Health, 2018 Background: The Middle East respiratory syndrome (MERS) has been reported for the first time infecting a human being since 2012. The WHO was notified of 27 countries have reported cases of MERS, the majority of these cases occur in the Arabian Peninsula,
Samy Kasem +12 more
doaj +1 more source
MERS-CoV– Low risk to Canadians
Canada Communicable Disease Report, 2014 Middle East respiratory syndrome - Coronavirus (MERS-CoV) -- is a novel coronavirus that has caused a number of community-acquired cases and health care associated outbreaks in Saudi Arabia and the United Arab Emirates (UAE) as well as sporadic cases in other countries, especially in the Middle East.
M, Saboui +3 more
openaire +2 more sources
Domestic Pig Unlikely Reservoir for MERS-CoV [PDF]
Emerging Infectious Diseases, 2017 We tested the suitability of the domestic pig as a model for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Inoculation did not cause disease, but a low level of virus replication, shedding, and seroconversion were observed. Pigs do not recapitulate human MERS-CoV and are unlikely to constitute a reservoir in nature.
Emmie de Wit +11 more
openaire +3 more sources
MicrobiologyOpen, Volume 15, Issue 3, June 2026.Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq +2 more
wiley +1 more source
Organoids: From Bench to Bedside Applications
MedComm, Volume 7, Issue 6, June 2026.Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source