Results 71 to 80 of about 27,602 (177)

Rigidity of the Outer Shell Predicted by a Protein Intrinsic Disorder Model Sheds Light on the COVID-19 (Wuhan-2019-nCoV) Infectivity [PDF]

, 2020
The world is currently witnessing an outbreak of a new coronavirus spreading quickly across China and affecting at least 24 other countries. With almost 65,000 infected, a worldwide death toll of at least 1370 (as of 14 February 2020), and with the ...
Dunker, A. Keith, Foster, James A., Goh, Gerard Kian-Meng, Uversky, Vladmir N.   +3 more
core   +1 more source

MERS-CoV– Low risk to Canadians

Canada Communicable Disease Report, 2014
Middle East respiratory syndrome - Coronavirus (MERS-CoV) -- is a novel coronavirus that has caused a number of community-acquired cases and health care associated outbreaks in Saudi Arabia and the United Arab Emirates (UAE) as well as sporadic cases in other countries, especially in the Middle East.
M, Saboui, F, Reyes-Domingo, E, Levreault, T, Mersereau   +3 more
openaire   +2 more sources

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

On-site detection of MERS-CoV infections in a camel slaughterhouse in Kenya using a commercial rapid antigen test

Frontiers in Veterinary Science
BackgroundMiddle East respiratory syndrome coronavirus (MERS-CoV) poses a significant public health risk, with dromedary camels being the primary reservoir hosts.
Brian Maina Ogoti, Brian Maina Ogoti, Brian Maina Ogoti, Victor Riitho, Victor Riitho, Victor Riitho, Jordi Rodon, Nyamai Mutono, Nyamai Mutono, Nyamai Mutono, Julia Tesch, Julius Oyugi, Marianne W. Mureithi, Marianne W. Mureithi, Victor M. Corman, Victor M. Corman, Victor M. Corman, Christian Drosten, Christian Drosten, Christian Drosten, Johanna Wildemann, Samuel M. Thumbi, Samuel M. Thumbi, Samuel M. Thumbi, Samuel M. Thumbi, Marcel A. Müller, Marcel A. Müller   +26 more
doaj   +1 more source

MERS-CoV (Middle East Respiratory Syndrome Coronavirus) outside the Arabian Peninsula an One Health approach: Understanding the role of wildlife, livestock and human in the virus dynamic [PDF]

, 2016
One of the big paradoxes of the MERS-CoV epidemiology is the apparent lack of human cases in large parts Africa where the virus and an animal host, the dromedary camel, are present.
Akhmetsadykov, Nourlan, Ayelet, Gelagay, Baubekova, Almagul, Ben Bencheikh, M.N., Bourgarel, Mathieu, Boussini, H., Chevalier, Véronique, Chu, Daniel K.W., El Berbri, Ikhlass, Fassi-Fihri, Ouafaa, Faye, Bernard, Fekadu, G., Grosbois, Vladimir, Maher, W., Miguel, Eve, Peiris, Malik, Perera, Ranawaka A.P.M., Roche, Benjamin, Roger, François, Shimekit, D., Traoré, Amadou, Van Kerkhove, Maria D.   +21 more
core  

Sparse evidence of MERS-CoV infection among animal workers living in Southern Saudi Arabia during 2012 [PDF]

, 2015
Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that primarily causes respiratory illness. We conducted a seroprevalence study of banked human serum samples collected in 2012 from Southern Saudi Arabia. Sera from 300
Alsahly, A, Anderson, BD, Gray, GC, Heil, GL, Khan, SU, Masri, MA, Memish, ZA, Peiris, JSM   +7 more
core   +1 more source

A novel coronavirus, MERS-CoV

Uirusu, 2013
A novel human coronavirus was identified in Saudi Arabia and Qatar as the causative agent of severe acute respiratory diseases in 2012. The virus was termed Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and is taken notice of important coronavirus caused severe diseases to human after the outbreak of severe acute respiratory syndrome (SARS ...
openaire   +3 more sources

Unraveling the drivers of MERS-CoV transmission [PDF]

Proceedings of the National Academy of Sciences, 2016
Significance Since it was discovered in 2012, Middle East respiratory syndrome coronavirus (MERS-CoV) has infected more than 1,700 persons, one-third of whom died, essentially in the Middle East. Persons can get infected by direct or indirect contact with dromedary camels, and although human-to-human transmission is not self-sustaining in the
Simon Cauchemez, Pierre Nouvellet, Anne Cori, Thibaut Jombart, Tini Garske, Hannah Clapham, Sean Moore, Harriet Linden Mills, Henrik Salje, Caitlin Collins, Isabel Rodriquez-Barraquer, Steven Riley, Shaun Truelove, Homoud Algarni, Rafat Alhakeem, Khalid AlHarbi, Abdulhafiz Turkistani, Ricardo J. Aguas, Derek A. T. Cummings, Maria D. Van Kerkhove, Christl A. Donnelly, Justin Lessler, Christophe Fraser, Ali Al-Barrak, Neil M. Ferguson   +24 more
openaire   +6 more sources

Comparative evaluation of noncanonical amino acids as site‐specific NMR probes for the complex of E. coli SSB with single‐stranded DNA without isotope labelling

The FEBS Journal, EarlyView.
Genetic encoding of noncanonical amino acids (ncAA) enables their site‐specific installation in proteins. This work compares the nuclear magnetic resonance (NMR) performance of different ncAAs in a large protein−DNA complex (~ 100 kDa) without isotope labelling. The ncAAs deliver readily detectable NMR signals in the complex between E.
Sreelakshmi Mekkattu Tharayil, Haocheng Qianzhu, Elwy H. Abdelkader, Adarshi P. Welegedara, Josemon George, Christoph Nitsche, Thomas Huber, Gottfried Otting   +7 more
wiley   +1 more source

Domestic Pig Unlikely Reservoir for MERS-CoV [PDF]

Emerging Infectious Diseases, 2017
We tested the suitability of the domestic pig as a model for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Inoculation did not cause disease, but a low level of virus replication, shedding, and seroconversion were observed. Pigs do not recapitulate human MERS-CoV and are unlikely to constitute a reservoir in nature.
Emmie de Wit, Friederike Feldmann, Eva Horne, Cynthia Martellaro, Elaine Haddock, Trenton Bushmaker, Kyle Rosenke, Atsushi Okumura, Rebecca Rosenke, Greg Saturday, Dana Scott, Heinz Feldmann   +11 more
openaire   +3 more sources