Results 71 to 80 of about 59,724 (178)

Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 26, 10 July 2026.
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao   +9 more
wiley   +1 more source

p‐Sulfonatocalix[4]arene‐Based Ratiometric Fluorescence Chemosensor Array for the Differential Detection of Polycationic Peptides

open access: yesChemistryEurope, Volume 4, Issue 7, July 2026.
A ratiometric fluorescence chemosensor array based on pyrene‐functionalized calixarenes enables complexation‐induced aggregation sensing of polycationic peptides in water. The system discriminates closely related sequences differing by minimal arginine content, including biologically relevant coronavirus spike protein cleavage‐site motifs, highlighting
Joana N. Martins   +7 more
wiley   +1 more source

MERS-CoV: Bridging the Knowledge Gaps

open access: yesOman Medical Journal, 2014
Since its emergence in September 2012 and as of 30 April 2014, there have been 424 cases of the Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) reported to public health authorities worldwide (15 countries). This tally includes 95 healthcare workers (22%) and 131 deaths (mortality rate of 31%).1 To date, only two laboratory confirmed cases have
Abdullah Balkhair   +4 more
openaire   +3 more sources

Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD

open access: yesCell Reports, 2019
Summary: Middle East respiratory syndrome coronavirus (MERS-CoV) emerged into the human population in 2012 and has caused substantial morbidity and mortality. Potently neutralizing antibodies targeting the receptor-binding domain (RBD) on MERS-CoV spike (
Nianshuang Wang   +17 more
doaj   +1 more source

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

open access: yesJournal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu   +3 more
wiley   +1 more source

ACE2‐ and HR2‐Mimetic Peptides Inhibit Replication of Two SARS‐CoV‐2 Variants

open access: yesJournal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Several therapeutic approaches to inhibiting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) focus on blocking the virus's entry mechanism. This can be blocked in two ways: by interacting with the receptor‐binding domain (RBD) of the spike protein and human angiotensin‐converting enzyme 2 (ACE2), and by blocking viral‐cellular ...
Melvin E. Zúñiga‐Hernández   +5 more
wiley   +1 more source

MERS-CoV– Low risk to Canadians

open access: yesCanada Communicable Disease Report, 2014
Middle East respiratory syndrome - Coronavirus (MERS-CoV) -- is a novel coronavirus that has caused a number of community-acquired cases and health care associated outbreaks in Saudi Arabia and the United Arab Emirates (UAE) as well as sporadic cases in other countries, especially in the Middle East.
M, Saboui   +3 more
openaire   +2 more sources

Host-directed therapies for improving poor treatment outcomes associated with the middle east respiratory syndrome coronavirus infections

open access: yesInternational Journal of Infectious Diseases, 2015
Three years after its first discovery in Jeddah Saudi Arabia, the novel zoonotic pathogen of humans, the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) continues to be a major threat to global health security.1 Sporadic community acquired cases ...
Alimuddin Zumla   +7 more
doaj   +1 more source

MERS-CoV: An Epidemic Whirlwind

open access: yesBiology and Medicine, 2016
Corona virus as a Middle East Respiratory Syndrome (MERS) considered being a new complicated disease; it infects the epithelial cells in the respiratory and/or intestinal tracts, thus causing disease in epidemic proportions. The situation is exacerbated by either a short incubation period between 2-7 days or between 12-14 days.
Ilham Qattan, Aljohani A
openaire   +1 more source

Serological evidence of MERS-CoV and HKU8-related CoV co-infection in Kenyan camels

open access: yesEmerging Microbes and Infections, 2019
Dromedary camels are important reservoir hosts of various coronaviruses, including Middle East respiratory syndrome coronavirus (MERS-CoV) that cause human infections.
Wei Zhang   +19 more
doaj   +1 more source

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