Results 71 to 80 of about 59,724 (178)
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao +9 more
wiley +1 more source
A ratiometric fluorescence chemosensor array based on pyrene‐functionalized calixarenes enables complexation‐induced aggregation sensing of polycationic peptides in water. The system discriminates closely related sequences differing by minimal arginine content, including biologically relevant coronavirus spike protein cleavage‐site motifs, highlighting
Joana N. Martins +7 more
wiley +1 more source
MERS-CoV: Bridging the Knowledge Gaps
Since its emergence in September 2012 and as of 30 April 2014, there have been 424 cases of the Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) reported to public health authorities worldwide (15 countries). This tally includes 95 healthcare workers (22%) and 131 deaths (mortality rate of 31%).1 To date, only two laboratory confirmed cases have
Abdullah Balkhair +4 more
openaire +3 more sources
Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD
Summary: Middle East respiratory syndrome coronavirus (MERS-CoV) emerged into the human population in 2012 and has caused substantial morbidity and mortality. Potently neutralizing antibodies targeting the receptor-binding domain (RBD) on MERS-CoV spike (
Nianshuang Wang +17 more
doaj +1 more source
Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu +3 more
wiley +1 more source
ACE2‐ and HR2‐Mimetic Peptides Inhibit Replication of Two SARS‐CoV‐2 Variants
ABSTRACT Several therapeutic approaches to inhibiting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) focus on blocking the virus's entry mechanism. This can be blocked in two ways: by interacting with the receptor‐binding domain (RBD) of the spike protein and human angiotensin‐converting enzyme 2 (ACE2), and by blocking viral‐cellular ...
Melvin E. Zúñiga‐Hernández +5 more
wiley +1 more source
MERS-CoV– Low risk to Canadians
Middle East respiratory syndrome - Coronavirus (MERS-CoV) -- is a novel coronavirus that has caused a number of community-acquired cases and health care associated outbreaks in Saudi Arabia and the United Arab Emirates (UAE) as well as sporadic cases in other countries, especially in the Middle East.
M, Saboui +3 more
openaire +2 more sources
Three years after its first discovery in Jeddah Saudi Arabia, the novel zoonotic pathogen of humans, the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) continues to be a major threat to global health security.1 Sporadic community acquired cases ...
Alimuddin Zumla +7 more
doaj +1 more source
MERS-CoV: An Epidemic Whirlwind
Corona virus as a Middle East Respiratory Syndrome (MERS) considered being a new complicated disease; it infects the epithelial cells in the respiratory and/or intestinal tracts, thus causing disease in epidemic proportions. The situation is exacerbated by either a short incubation period between 2-7 days or between 12-14 days.
Ilham Qattan, Aljohani A
openaire +1 more source
Serological evidence of MERS-CoV and HKU8-related CoV co-infection in Kenyan camels
Dromedary camels are important reservoir hosts of various coronaviruses, including Middle East respiratory syndrome coronavirus (MERS-CoV) that cause human infections.
Wei Zhang +19 more
doaj +1 more source

