Results 71 to 80 of about 252,954 (227)

Three‐Dimensional Magnetic Multi‐Metallic Nanozymes With Colorimetric and Catalytic Amplification for Rapid and Highly‐Sensitive Detection of Influenza A

Exploration, EarlyView.
The application of nanozymes in LFIA greatly improved the situation of insufficient colorimetric signals by catalytic reaction. 3D magnetic multi‐metallic nanozymes integrated the characteristics of great magnetism, enhanced colorimetric signal, and outstanding POD‐like activity, and were applied to LFIA for rapid and accurate detection of Influenza A ...
Zhenzhen Liu, Pengyou Zhou, Xiaofei Jia, Xiaoxian Liu, Yong Yang, Yansong Sun, Rui Xiao   +6 more
wiley   +1 more source

MERS-CoV-induced microRNA (miRNA) expression in primary human airway epithelial cells (GSE81852).

, 2021
Two differentially expressed miRNAs (hsa-miR-4697-5p, hsa-miR-4521) clearly distinguish MERS-coronavirus (icMERS) infected from MOCK infected control cells; over 50% of predicted gene targets of both miRNAs are implicated in pro-viral, antiviral and/or ...
Harris A. Weisz (7305551), Donald S. Prough (7305566), Steve G. Widen (11502308), Helen L. Hellmich (7305569), Stacy L. Sell (7305545)   +4 more
core   +1 more source

A novel luciferase immunosorbent assay performs better than a commercial enzyme-linked immunosorbent assay to detect MERS-CoV specific IgG in humans and animals

Biosafety and Health, 2019
The Middle East respiratory syndrome (MERS) is a lethal zoonosis caused by MERS coronavirus (MERS-CoV) and poses a significant threat to public health worldwide.
Wenling Wang, Tianyu Wang, Yao Deng, Peihua Niu, Ruhan A, Jincun Zhao, Malik Peiris, Shixing Tang, Wenjie Tan   +8 more
doaj   +1 more source

A novel coronavirus, MERS-CoV

Uirusu, 2013
A novel human coronavirus was identified in Saudi Arabia and Qatar as the causative agent of severe acute respiratory diseases in 2012. The virus was termed Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and is taken notice of important coronavirus caused severe diseases to human after the outbreak of severe acute respiratory syndrome (SARS ...
openaire   +3 more sources

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis

Phytotherapy Research, EarlyView.
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang, YongJun Du, Yanmei Hou, Liangliang Hao, Zhen Chen, Haoyang Xie, Chuantao Zhang, Lei Li   +7 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Inhibition of the IFN-α JAK/STAT pathway by MERS-CoV and SARS-CoV-1 proteins in human epithelial cells

, 2022
Coronaviruses (CoVs) have caused several global outbreaks with relatively high mortality rates, including Middle East Respiratory Syndrome coronavirus (MERS)-CoV, which emerged in 2012, and Severe Acute Respiratory Syndrome (SARS)-CoV-1, which appeared ...
Siobhan Gargan (11907946), Yamei Zhang (2935029), Fiona M Roche (18705), Matthew Frieman (338380), Nigel Stevenson (12597031)   +4 more
core   +1 more source

Detection of the Middle East Respiratory Syndrome Coronavirus Genome in an Air Sample Originating from a Camel Barn Owned by an Infected Patient

mBio, 2014
Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel betacoronavirus that has been circulating in the Arabian Peninsula since 2012 and causing severe respiratory infections in humans.
Esam I. Azhar, Anwar M. Hashem, Sherif A. El-Kafrawy, Sayed Sartaj Sohrab, Asad S. Aburizaiza, Suha A. Farraj, Ahmed M. Hassan, Muneera S. Al-Saeed, Ghazi A. Jamjoom, Tariq A. Madani   +9 more
doaj   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source