Results 151 to 160 of about 338,568 (266)

The evolutionary landscape and serotypic dynamics of avian infectious bronchitis virus from spike protein

iMetaOmics, Volume 3, Issue 1, March 2026.
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang, Zongxi Han, Chuangchao Zou, Yihui Huang, Shiping Sun, Ouyang Peng, Usama Ashraf, Qiuping Xu, Yao Ge, Qixiang Kang, Xiuli Ma, Xinheng Zhang, Ye Zhao, Xin Yang, Hongning Wang, Guozhong Zhang, Qingmei Xie, Mang Shi, Yongsen Ruan, Min Liao, Shengwang Liu, Yongchang Cao   +21 more
wiley   +1 more source

Complement Hyperactivation Is Mediated by Alternative and Lectin Pathways During Early Phase of Severe Vaccination‐Omicron BA.5 Infection

Journal of Medical Virology, Volume 98, Issue 3, March 2026.
ABSTRACT Complement temporal activation kinetics, activation pathways, and their relationship with thromboinflammation and antibody responses in severe vaccination‐COVID‐19 remains unclear. Based on a vaccinated‐infected cohort, we analyzed complement immune responses across mild to critical COVID‐19 cases by a dynamic model.
Jinpeng Cao, Gang Yang, Tingting Cui, Jian Qin, Deyi Huang, Shiqin Jin, Xiaoyun Yang, Mingzhu Huang, Xiaoling Su, Siyi Liu, Yingjiao Xia, Shidong Deng, Chengna Luo, Zhuxiang Zhao, Yunhui Zhang, Nanshan Zhong, Zhongfang Wang   +16 more
wiley   +1 more source

Total Breakthrough Strategy in Hydrophilic Interaction Chromatography for IP‐RPLC × HILIC Separation of Oligonucleotides

Journal of Separation Science, Volume 49, Issue 3, March 2026.
ABSTRACT Solvent mismatch between the two dimensions is one of the main limitations in two‐dimensional liquid chromatography (2D‐LC) and presents a significant challenge for method development. Although 2D‐LC provides a powerful means to increase peak capacity for oligonucleotides analysis compared to conventional one‐dimensional LC, solvent ...
Megane K. Aebischer, Yusraa Abdurahman, Davy Guillarme   +2 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Clinical Characteristics and Gene Mutations of Hereditary Spherocytosis in 59 Chinese Children

Molecular Genetics &Genomic Medicine, Volume 14, Issue 3, March 2026.
Summary of the causative genes' spectrum of 59 Chinese HS Children patients. The schematic diagram of ankyrin, β‐spectrin, α‐spectrin, and band three protein domains with ANK1, SPTB, SPTA1, and SLC4A1 mutations. Distribution of mutations in the exons of ANK1 and SPTB genes.
Yuzhuopu Li, Yang Wang, Tao Liu, Li Xiao, Lan Huang, Yongjie Zhang, Yan Xiang, Jie Yu   +7 more
wiley   +1 more source

The Impact, Role and Experiences of Nurses Working in Medical Quarantine During the COVID‐19 Pandemic: A Narrative Review

Nursing Open, Volume 13, Issue 3, March 2026.
ABSTRACT Aim To understand the impact, role and experience of nurses working in medical hotel quarantine during the COVID‐19 pandemic. Background Medical Hotel Quarantine was staffed predominantly by nurses to prevent the spread of COVID‐19 when people who were COVID‐19 positive were unable to isolate safely in their communities.
Tania Avila, Diana Jefferies, Lucie M. Ramjan   +2 more
wiley   +1 more source

Large language models for bioinformatics

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract With the rapid advancements in large language model technology and the emergence of bioinformatics‐specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational characteristics, and diverse applications.
Wei Ruan, Yanjun Lyu, Jing Zhang, Jiazhang Cai, Peng Shu, Yang Ge, Yao Lu, Shang Gao, Yue Wang, Peilong Wang, Lin Zhao, Tao Wang, Yufang Liu, Luyang Fang, Ziyu Liu, Zhengliang Liu, Yiwei Li, Zihao Wu, Junhao Chen, Hanqi Jiang, Yi Pan, Zhenyuan Yang, Jingyuan Chen, Shizhe Liang, Wei Zhang, Terry Ma, Yuan Dou, Jianli Zhang, Xinyu Gong, Qi Gan, Yusong Zou, Zebang Chen, Yuanxin Qian, Shuo Yu, Jin Lu, Kenan Song, Xianqiao Wang, Andrea Sikora, Gang Li, Xiang Li, Quanzheng Li, Yingfeng Wang, Lu Zhang, Yohannes Abate, Lifang He, Wenxuan Zhong, Rongjie Liu, Chao Huang, Wei Liu, Ye Shen, Ping Ma, Hongtu Zhu, Yajun Yan, Dajiang Zhu, Tianming Liu   +54 more
wiley   +1 more source

MERS-CoV

, 2019
About the Special Issue Editors Fang Li is an Associate Professor in the Department of Veterinary and Biomedical Sciences at the University of Minnesota. His main line of research examines the invasion mechanisms of viruses. Specifically, his group investigates the structures and functions of virus-surface proteins that mediate receptor recognition and
openaire   +2 more sources

Genomic architecture of the resistance to Phytophthora cactorum 2 (RPc2) locus in strawberry (Fragaria × ananassa)

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Phytophthora crown rot, caused by Phytophthora cactorum, is a soilborne disease with broad impacts on cultivated strawberry (Fragaria × ananassa). A resistance locus, RPc2, was previously identified in octoploid strawberries, but the underlying genomic architecture and causal genes remained uncharacterized.
Hyeondae Han, Youngjae Oh, Yoon Jeong Jang, Saket Chandra, Upinder Gill, Sujeet Verma, Young‐Hee Noh, Sachiko Isobe, Dominique D. A. Pincot, Glenn S. Cole, Randi A. Famula, Mitchell J. Feldmann, Steven J. Knapp, Vance M. Whitaker, Seonghee Lee   +14 more
wiley   +1 more source

Mer

, 2022
Driessen, Henk, Driessen, Henk > Auteur
openaire   +1 more source