Results 91 to 100 of about 13,648 (298)

Medication adherence and persistence in the treatment of Canadian ulcerative colitis patients: analyses with the RAMQ database

BMC Gastroenterology, 2013
Background Although high non-adherence to medication has been noticed for ulcerative colitis (UC), little is known about adherence to mesalamine treatments and determinants that can predict adherence.
Lachaine Jean, Yen Linnette, Beauchemin Catherine, Hodgkins Paul   +3 more
doaj   +1 more source

Oral 5-aminosalicylic acid for maintenance of medically-induced remission in Crohn's disease [PDF]

, 2016
Background The prevention of relapse is a major issue in the management of Crohn's disease. Corticosteroids, the mainstay of treatment of acute exacerbations, are not effective for maintenance of remission and its chronic use is limited by numerous ...
Akobeng, Anthony, Gordon, Morris, Macdonald, John, Zang, Dongni   +3 more
core   +1 more source

Myelodysplastic Syndrome in a Patient With Cronkhite‐Canada Syndrome

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Cronkhite‐Canada Syndrome (CCS) is a rare non‐hereditary gastroenterological polyposis syndrome without a clear etiology. Myelodysplastic syndromes (MDS) are clonal hematological disorders. Immune dysregulation has been posited as a contributor to the development of both. A 70‐year‐old man developed chronic diarrhea, dysgeusia, and onycholysis.
Kevin G. Shim, Kevork Khadarian, Jewel Samadder, Jiehao Zhou, Cecilia Arana Yi   +4 more
wiley   +1 more source

Update on the management of ulcerative colitis: treatment and maintenance approaches focused on MMX® mesalamine

Clinical Pharmacology: Advances and Applications, 2012
Kavinderjit Nanda, Alan C MossCenter for Inflammatory Bowel Disease, BIDMC/Harvard Medical School, Boston, MA, USAAbstract: Ulcerative colitis (UC) is a chronic inflammatory disease of the colon that typically manifests as diarrhea, abdominal pain, and ...
Nanda K, Moss AC
doaj  

Endoscopic scores for inflammatory bowel disease in the era of 'mucosal healing'. old problem, new perspectives [PDF]

, 2016
The importance of the endoscopic evaluation in inflammatory bowel disease (IBD) management has been recognized for many years. However, the modalities for reporting endoscopic activity represent an ongoing challenge.
Corleto, Vito Domenico, DELLE FAVE, Gianfranco, Desideri, F, DI GIULIO, Emilio, Menasci, F, Pagnini, C   +5 more
core   +1 more source

Prescribing Inflammatory Bowel Disease Medications in Chronic Kidney Disease: A Practical Guide

Alimentary Pharmacology &Therapeutics, Volume 62, Issue 4, Page 400-418, August 2025.
Most therapies used in inflammatory bowel disease appear safe and effective when used in chronic kidney disease including on renal replacement therapy, particularly biologic therapies. Some caution should be considered when using conventional therapies and JAK inhibitors.
Lynna Chen, Ashish Srinivasan, Suet‐Wan Choy, Jeffrey Van, Habeeb Habeeb, Andrew Nguyen, Abhinav Vasudevan   +6 more
wiley   +1 more source

Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease [PDF]

, 2017
Background/Aims: Identifying predictors of endoscopic recurrence (ER) has become very important to guide the decision of postoperative strategy. This study aimed to determine the rate of endoscopic recurrence until 12 months after ileocolic resection for
Carvalho, Pedro Boal, Cotter, José Almeida Berkeley, Gonçalves, Tiago Cúrdia, Monteiro, Sara, Moreira, Maria João   +4 more
core   +1 more source

High‐frequency oscillations >250 Hz in people with Down syndrome and associated Alzheimer's disease dementia

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION Alzheimer's disease (AD) dementia has near full penetrance in adults with Down syndrome (DS) and is strongly linked to late‐onset myoclonic epilepsy in Down syndrome (LOMEDS). However, promising biomarkers of epileptogenicity, such as high‐frequency oscillations (HFOs >250 Hz), have not been studied. This study is the first to use
Christos Panagiotis Lisgaras, Sandra Giménez, María Carmona‐Iragui, Lucia Maure‐Blesa, Esther Blessing, Juan Fortea, Ricardo S. Osorio   +6 more
wiley   +1 more source

Distal Ulcerative Colitis Refractory to Rectal Mesalamine: Role of Transdermal Nicotine versus Oral Mesalamine

Canadian Journal of Gastroenterology, 2002
BACKGROUND: Distal ulcerative colitis usually responds to treatment with rectal mesalamine, but the management of refractory cases is poorly defined.AIM: To evaluate the possible therapeutic benefit of transdermal nicotine versus oral mesalamine.PATIENTS AND METHODS: Thirty patients with left-sided ulcerative colitis unresponsive to treatment with a ...
Guslandi M, Frego R, Viale E, TESTONI , PIER ALBERTO   +3 more
openaire   +6 more sources

Variability in intestinal drug metabolizing enzymes and transporters in Crohn's disease and potential impact on oral drug absorption

British Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 2028-2044, July 2025.
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia, Brahim Achour, Zubida M. Al‐Majdoub, Amin Rostami‐Hodjegan, Jill Barber   +4 more
wiley   +1 more source