Results 201 to 210 of about 9,412 (255)

Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease.

Inflammatory Bowel Diseases, 2021
BACKGROUND Some patients with inflammatory bowel disease (IBD) who were under mesalamine treatment develop adverse reactions called "mesalamine allergy," which includes high fever and worsening diarrhea.
Kaoru Suzuki, Y. Kakuta, Takeo Naito, T. Takagawa, H. Hanai, H. Araki, Yu Sasaki, H. Sakuraba, M. Sasaki, T. Hisamatsu, S. Motoya, T. Matsumoto, Motoyuki Onodera, Y. Ishiguro, H. Nakase, A. Andoh, S. Hiraoka, M. Shinozaki, T. Fujii, T. Katsurada, Taku Kobayashi, M. Fujiya, T. Otsuka, N. Oshima, Yasuo Suzuki, Yuichirou Sato, R. Hokari, M. Noguchi, Y. Ohta, M. Matsuura, Y. Kawai, K. Tokunaga, Masao Nagasaki, Hisaaki Kudo, N. Minegishi, Daisuke Okamoto, Yusuke Shimoyama, Rintaro Moroi, Masatake Kuroha, H. Shiga, Dalin Li, D. McGovern, Y. Kinouchi, A. Masamune, K. Ikeya, A. Nishida, Shoko Nakagawa, M. Miura, T. Toyonaga, K. Onodera, M. Takahara, S. Yanai, S. Ishihara, M. Nagahori, K. Matsuoka, K. Arai, S. Mizuno, M. Naganuma, Shiro Nakamura, Tomoaki Ishikawa, Hiroki Nakajima, H. Terasaki, Rumiko Saito, I. Amemiya, H. Ohyama, Kai Korekawa, Hideya Iwaki, Sayumi Takahashi, Motoki Makuuchi, Y. Inomata, Fumiko Shimoda, Takahiro Takahashi, Kota Yano, Izuru Abe, T. Handa, Y. Masu, Kasumi Hishinuma, Y. Kanazawa, Tomoya Kimura, K. Negoro, Mai Kato   +80 more
semanticscholar   +1 more source

Mesalamine-induced granulomatous hepatitis

The American Journal of Gastroenterology, 1999
A 42-yr-old man with ulcerative colitis was admitted for investigation of prolonged fever associated with cholestatic liver tests. Endoscopic retrograde cholangiopancreatography demonstrated a normal biliary tree, and liver biopsy showed granulomata.
Francis Salamon, Gerald Fraser, Marius Braun, Margareta Kunin, Ran Tur Kaspa   +4 more
openaire   +3 more sources

Mucoadhesive Mesalamine Prodrug Nanoassemblies to Target Intestinal Macrophages for the Treatment of Inflammatory Bowel Disease.

ACS Nano
While mesalamine, a 5-aminosalicylic acid (5-ASA), is pivotal in the management of inflammatory bowel disease (IBD) through both step-up and top-down approaches in clinical settings, its widespread utilization is limited by low bioavailability at the ...
Byeongmin Park, Geonhee Han, Do Young Jin, Ki Cheol Gil, Dongwon Shin, Jongwon Lee, Jung Yeon Park, Hochung Jang, Daeho Park, Sangmin Lee, Kwangmeyung Kim, Yoosoo Yang, Yongju Kim, Jun-Seob Kim, Sun Hwa Kim, M. Shim   +15 more
semanticscholar   +1 more source

Asacol (Mesalamine)

Gastroenterology Nursing, 1992
Asacol (mesalamine) is a delayed release pH-sensitive, polymer-coated, oral preparation of 5-ASA which releases the drug in the terminal ileum and colon for the treatment of mildly to moderately active ulcerative colitis. Treatment modalities using Asacol appear to be an alternative for sulfasalazine-sensitive patients as well as potential first-line ...
openaire   +2 more sources

Physiologically Based Biopharmaceutics Modeling Coupled with Biopredictive Dissolution in Development of Bioequivalent Formulation for Mesalamine Enteric Coated Tablet: A Tough Nut to Crack.

AAPS PharmSciTech
Mesalamine is a locally acting anti-inflammatory drug used to treat mild to moderate ulcerative colitis. Because of complex formulation principle and high in vivo variability, development of bioequivalent formulation for mesalamine is challenging ...
Sivacharan Kollipara, Pankaj Kumar Prabhat, Paramita Saha, Saurabh Gupta, Venkat Ramana Naidu, Tausif Ahmed   +5 more
semanticscholar   +1 more source

Development and In Vivo Evaluation of Pectin Based Enteric Coated Microparticles Loaded with Mesalamine and Saccharomyces boulardii for Management of Ulcerative Colitis.

Assay and drug development technologies, 2021
Mesalamine is the first-line choice of drug for ulcerative colitis management. However, due to the nontargeted delivery of mesalamine, it shows side effects. The possible impact of mesalamine can be improved by coated microparticles in combination with S.
Amandeep Singh, U. Mandal, R. Narang
semanticscholar   +1 more source

Pentasa (Mesalamine)

Gastroenterology Nursing, 1993
Pentasa (mesalamine) is a newly released oral 5-aminosalicylic acid capsule marketed by Marion Merrel Dow Inc., for the induction of remission and for the treatment of mildly to moderately active ulcerative colitis. Ulcerative colitis is a chronic inflammatory disease and the most common form of inflammatory bowel disease, which is a debilitating and ...
openaire   +2 more sources

Novel Bioenhanced Curcumin With Mesalamine for Induction of Clinical and Endoscopic Remission in Mild-to-Moderate Ulcerative Colitis

Journal of Clinical Gastroenterology, 2020
Background and Aims: The aim of this study was to assess the efficacy and safety of a novel, hydrophilic, bioenhanced curcumin (BEC) as add-on therapy in inducing clinical and endoscopic remission in mild to moderately active ulcerative colitis (UC ...
R. Banerjee, P. Pal, A. Penmetsa, Pradip Kathi, Ganesh Girish, I. Goren, D. Reddy   +6 more
semanticscholar   +1 more source

Thiopurines are superior to mesalamine for preventing postoperative recurrence in patients with Crohn's disease and two or more risk factors

Journal of Digestive Diseases, 2021
To confirm the hypothesis that thiopurines are better than mesalamine for preventing postoperative recurrence of Crohn's disease (CD) in patients with more than two risk factors.
Z. Huang, Qingfan Yang, Jian Tang, Miao Li, K. Chao, Xiang Gao   +5 more
semanticscholar   +1 more source

An Advanced Study on Development and Validation of RP-HPLC Method for Simultaneous Estimation of Mesalamine and Prednisolone in Bulk and Formulation

Technological Innovation in Pharmaceutical Research Vol. 9, 2021
In accordance with the analytical parameter mentioned in the ICH guidelines, a simple, precise, accurate, sensitive, and economical reversed phase high performance liquid chromatographic method was developed and validated for the simultaneous ...
N. K. Drisya, S. Prasanth, V. Akhila, K. Sruthi   +3 more
semanticscholar   +1 more source