Evaluation of mesalazine polymeric conjugate in the treatment of actinic proctitis in rats
Acta Cirúrgica Brasileira, 2021 Purpose: The present study aimed at testing a new formulation of mesalazine linked to chondroitin sulfate and its components alone in the treatment of actinic proctitis in rats.
Vinícius Rodrigues Taranto Nunes +9 more
doaj +1 more source
Treatment of diverticular disease: an update on latest evidence and clinical implications [PDF]
, 2018 Background: Diverticular disease (DD) is a common condition, especially in Western countries. In about 80% of patients, colonic diverticula remain asymptomatic (diverticulosis), while approximately 20% of patients may develop abdominal symptoms ...
Annibale, B, Carabotti, M
core +2 more sources
A mechanistic multi-centre, parallel group, randomised placebo controlled trial of Mesalazine for treatment of irritable bowel syndrome with diarrhoea (IBS-D) [PDF]
, 2015 Introduction: Immune activation has been reported in the mucosa of irritable bowel syndrome patients with diarrhoea (IBS-D) and some small studies have suggested that Mesalazine may reduce symptoms.
Abed Zaitoun +50 more
core +1 more source
Clinical and economic efficiency of multi-matrix mesalazine in ulcerative colitis treatment in the healthcare system of the Republic of Kazakhstan [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2019 Aim: Clinical and economic evaluation of multi-matrix mesalazine 1200 mg compared with prolonged-release mesalazine at a dose of 500mg for the treatment of patients aged 18 years and older with the diagnosis of ulcerative colitis in the phase of ...
Alima Almadiyeva +4 more
doaj +1 more source
New method for preparation of delivery systems of poorly soluble drugs on the basis of functionalized mesoporous MCM-41 nanoparticles [PDF]
, 2014 MCM-41 silica with spherical morphology and small particle sizes (100 nm) was synthesized and modified by post-synthesis method with amino and/or carboxylic groups.
Aleksandrov, H. E. +7 more
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Intestinal Research, 2017 Background/Aims: This study assessed the efficacy and safety of high-dose multimatrix mesalazine once-daily (QD) compared to another form of high-dose mesalazine.Methods: In this multicenter, randomized, double-blind study, 280 patients with mildly to ...
Haruhiko Ogata +4 more
doaj +1 more source
Pediatric case of mesalazine‐induced interstitial nephritis with literature review [PDF]
, 2013 We present the case of a 14‐year‐old boy with ulcerative colitis who was diagnosed with mesalazine‐induced interstitial nephritis ( M‐IIN ). Improvement in renal function occurred with discontinuation of mesalazine and corticosteroid therapy.
Co, Maridine L., Gorospe, Emmanuel C.
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Intestinal Research, 2017 Background/Aims: This study compared the efficacy of once-daily administration of multimatrix mesalazine 2.4 g/day with multiple-dose mesalazine for the maintenance of remission.Methods: In this multicenter, randomized, double-blind study, 203 patients ...
Haruhiko Ogata +5 more
doaj +1 more source
Evolution and predictive factors of relapse in ulcerative colitis patients treated with mesalazine after a first course of corticosteroids. [PDF]
, 2011 INTRODUCTION: Mesalazine remains the first line treatment for the induction and the maintenance of remission in mild to moderate ulcerative colitis (UC).
Belaiche, Jacques +3 more
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Ulcerative colitis associated with nephrotic syndrome after treatment with mesalazine developed into rectal carcinoma: a case study [PDF]
, 2016 BACKGROUND: Previous studies reported that nephrotic syndrome is associated with ulcerative colitis (UC) patients treated with mesalazine. Dysplasia associated with UC often develops into colorectal carcinoma.
Masatoshi Oya +6 more
core +1 more source