Results 141 to 150 of about 79,337 (314)

Dual‐Targeted Nanovesicles Induced Cancer Stem‐Like Cell Differentiation to Sensitize Hepatocellular Carcinoma Radiotherapy

Advanced Science, EarlyView.
The existence of Pin1 and Notch1 crosstalk is identified and verified in HCC, and the crucial function of this crosstalk in sustaining the aggressive phenotypes of CSCs and radioresistance. A biomimetic nanovesicle is now developed to block the crosstalk between Pin1 and Notch1 for inducing CSCs differentiation and sensitizing HCC radiotherapy ...
Hongmei Cao, Qian Wang, Yanan Niu, Shuxiang Wang, Haixue Jia, Dianyu Wang, Jinjian Liu, Wei Yuan, Lijun Yang, Jianfeng Liu   +9 more
wiley   +1 more source

Umbilical cord blood transplantation supplemented with the infusion of mesenchymal stem cell for an adolescent patient with severe aplastic anemia: a case report and review of literature

Patient Preference and Adherence, 2015
Chengxin Luan, Runzhe Chen, Baoan Chen, Jiahua Ding, Ming Ni Department of Hematology and Oncology (Key Department of Jiangsu Medicine), Zhongda Hospital, Medical School, Southeast University, Nanjing, Jiangsu Province, People’s Republic of China
Luan C, Chen R, Chen B, Ding J, Ni M
doaj  

Fetal Mesenchymal Stem-Cell Engraftment in Bone after In Utero Transplantation in a Patient with Severe Osteogenesis Imperfecta

, 2005
Katarina Le Blanc, Cecilia Götherström, Olle Ringdén, Moustapha Hassan, Robert P. McMahon, Edwin M. Horwitz, Göran Annerén, Ove Axelssön, Janice Nunn, Uwe Ewald, Solveig Nordén‐Lindeberg, Monika Jansson, Ann Dalton, Eva Åström, Magnus Westgren   +14 more
openalex   +1 more source

Mesenchymal stem cells from patients with chronic myeloid leukemia do not express BCR-ABL and have absence of chimerism after allogeneic bone marrow transplant [PDF]

, 2007
R.C.V. Carrara, M.D. Orellana, A.M. Fontes, P.V.B. Palma, S. Kashima, M.R. Mendes, M.A. Coutinho, J.C. Voltarelli, Dimas Tadeu Covas   +8 more
openalex   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

Treatment of resistant pure red cell aplasia after major abo‐incompatible bone marrow transplantation with human adipose tissue‐derived mesenchymal stem cells [PDF]

, 2007
Baijun Fang, Yongping Song, Robert Chunhua Zhao, Qin Han, Ying Cao   +4 more
openalex   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Correction: The synergistic effect of electroacupuncture and bone mesenchymal stem cell transplantation on repairing thin endometrial injury in rats. [PDF]

Stem Cell Res Ther, 2023
Xia L, Meng Q, Xi J, Han Q, Cheng J, Shen J, Xia Y, Shi L.   +7 more
europepmc   +1 more source

Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury

Advanced Science, EarlyView.
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley   +1 more source