Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan +8 more
wiley +1 more source
Effects of muscle energy technique along conventional physical therapy after mesenchymal stem cell transplantation in knee osteoarthritis patients. [PDF]
Ashraf F, Anwar K, Arshad H.
europepmc +1 more source
Matrix Viscoelasticity: The Overlooked Architect of Solid Tumour Evolution
Organ Medicine, EarlyView.
Ruixi Huang, Yupeng Guan
wiley +1 more source
Stem Cell‐Based Approaches for Neurotrophic Keratopathy: From Ocular Surface to Neuro‐Ophthalmology
ABSTRACT Neurotrophic keratopathy is an uncommon, but potentially sight‐threatening, corneal disorder that results from impaired trigeminal sensory innervation. The loss of corneal sensation disrupts epithelial stability, weakens wound healing, and may lead to persistent epithelial defects, stromal ulceration, and, in the most advanced cases, corneal ...
Matteo Capobianco, Marco Zeppieri
wiley +1 more source
Synergistic restoration of spinal cord injury through hyaluronic acid conjugated hydrogel-polydopamine nanoparticles combined with human mesenchymal stem cell transplantation. [PDF]
Kao Y +12 more
europepmc +1 more source
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova +10 more
wiley +1 more source
Therapeutic Potential of Different Injection Methods for Bone Marrow Mesenchymal Stem Cell Transplantation in Buslfan-Induced Male Rat Infertility. [PDF]
Abdelbaset S +4 more
europepmc +1 more source
A 3D‐bioprinted platform with stem cells activates “nerve‐bone” signaling by enabling the spatiotemporal delivery of Nell‐1. This activation enhances neurovascular and bone regeneration through the CYFIP1 cascade. In rat calvarial defects, the platform doubled bone regeneration and nerve repair and tripled vascular density, resulting in superior ...
Minjia Zhu +11 more
wiley +1 more source
Mesenchymal stem cell transplantation may be able to induce immunological tolerance in systemic lupus erythematosus. [PDF]
Barbado J.
europepmc +1 more source

