Magnetic cell delivery for the regeneration of musculoskeletal and neural tissues
Regenerative Therapy, 2018 Magnetic targeting is a cell delivery system using the magnetic labeling of cells and the magnetic field; it has been developed for minimally invasive cell transplantation.
Naosuke Kamei, Nobuo Adachi, Mitsuo Ochi
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Mesenchymal stem cells: a promising way in therapies of graft-versus-host disease
Cancer Cell International, 2020 It is well acknowledged that allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective treatment for numerous malignant blood diseases, which has also been applied to autoimmune diseases for more than a decade.
Xinyi Zhou +3 more
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Chondrogenic potential of human articular chondrocytes and skeletal stem cells: a comparative study
, 2014 Regenerative medicine strategies have increasingly focused on skeletal stem cells (SSCs), in response to concerns such as donor site morbidity, dedifferentiation and limited lifespan associated with the use of articular chondrocytes for cartilage repair.
Li, Siwei +3 more
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Overcoming the roadblocks to cardiac cell therapy using tissue engineering [PDF]
, 2017 Transplantations of various stem cells or their progeny have repeatedly improved cardiac performance in animal models of myocardial injury; however, the benefits observed in clinical trials have been generally less consistent.
Bolli, Roberto +12 more
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Platelet lysate as a serum substitute for 2D static and 3D perfusion culture of stromal vascular fraction cells from human adipose tissue [PDF]
, 2009 Fetal bovine serum (FBS) and fibroblast growth factor (FGF)-2 are key supplements for the culture of stromal vascular fraction (SVF) cells from adipose tissue, both for typical monolayer (2D) expansion and for streamlined generation of osteogenic ...
Alini, Mauro +8 more
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Autologous mesenchymal stem cell transplantation in stroke patients
Annals of Neurology, 2005 AbstractMesenchymal stem cell (MSC) transplantation improves recovery from ischemic stroke in animals. We examined the feasibility, efficacy, and safety of cell therapy using culture‐expanded autologous MSCs in patients with ischemic stroke. We prospectively and randomly allocated 30 patients with cerebral infarcts within the middle cerebral arterial ...
Oh Young, Bang +3 more
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Wharton’s jelly or bone marrow mesenchymal stromal cells improve cardiac function following myocardial infarction for more than 32 weeks in a rat model: a preliminary report [PDF]
, 2013 The therapeutic effect of mesenchymal stromal cells (MSCs) following myocardial infarction (MI) is small. This may be due to differences in cellular sources and donor age, route of administration, in vitro cellular manipulations and the short time course
Borgarelli, Michele +7 more
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Adult-Derived Human Liver Mesenchymal-Like Cells as a Potential Progenitor Reservoir of Hepatocytes?
Cell Transplantation, 2007 It is currently accepted that adult tissues may develop and maintain their own stem cell pools. Because of their higher safety profile, adult stem cells may represent an ideal candidate cell source to be used for liver cell therapies.
Mustapha Najimi +6 more
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Mesenchymal Stem Cell Insights: Prospects in Hematological Transplantation
Cell Transplantation, 2013 Adult stem cells have been proven to possess tremendous potential in the treatment of hematological disorders, possibly in transplantation. Mesenchymal stem cells (MSCs) are a heterogeneous group of cells in culture, with hypoimmunogenic character to avoid alloreactive T-cell recognition as well as inhibition of T-cell proliferation.
Shiu-Huey Chou +9 more
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Mesenchymal stem cells for management of rheumatoid arthritis : immune modulation, repair or both? [PDF]
, 2018 The authors are grateful for support to their research from Arthritis Research UK (grants 19271, 19429, 19667, 20050, 20775) and the Medical Research Council (grant no.
Ansboro, Sharon +2 more
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