Results 111 to 120 of about 1,363,551 (403)

Encapsulation of factor IX–engineered mesenchymal stem cells in fibrinogen–alginate microcapsules enhances their viability and transgene secretion

Journal of Tissue Engineering, 2012
Cell microencapsulation holds significant promise as a strategy for cellular therapies; however, inadequate survival and functionality of the enclosed cells limit its application in hemophilia treatment.
Bahareh Sayyar, Megan Dodd, Jianping Wen, Shirley Ma, Leah Marquez-Curtis, Anna Janowska-Wieczorek, Gonzalo Hortelano   +6 more
doaj   +1 more source

Dental mesenchymal stem cells [PDF]

Development, 2016
Mammalian teeth harbour mesenchymal stem cells (MSCs), which contribute to tooth growth and repair. These dental MSCs possess many in vitro features of bone marrow-derived MSCs, including clonogenicity, expression of certain markers, and following stimulation, differentiation into cells that have the characteristics of osteoblasts, chondrocytes and ...
openaire   +3 more sources

Ovalbumin sensitization and challenge increases the number of lung cells possessing a mesenchymal stromal cell phenotype [PDF]

, 2010
Background Recent studies have indicated the presence of multipotent mesenchymal stromal cells (MSCs) in human lung diseases. Excess airway smooth muscle, myofibroblasts and activated fibroblasts have each been noted in asthma, suggesting that ...
Adam M Goldsmith, Amy E Baek, Antonia P Popova, Bentley, J Kelley, J Kelley Bentley, Jing Lei, Marc B Hershenson, Marisa J Linn, Paul D Bozyk   +8 more
core   +6 more sources

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Synovial membrane mesenchymal stem cells: past life, current situation, and application in bone and joint diseases

Stem cell research & therapeutics, 2020
Mesenchymal stem cells (MSCs) can be isolated from not only bone marrow, but also various adult mesenchymal tissues such as periosteum, skeletal muscle, and adipose tissue.
Na Li, Jinfang Gao, L. Mi, Gailian Zhang, Liyun Zhang, Na Zhang, Rongxiu Huo, Junping Hu, Ke Xu   +8 more
semanticscholar   +1 more source

Trafficking of Mesenchymal Stem Cells

, 2011
In adult life mesenchymal stem cells (MSCs) reside primarily in the bone marrow and are defined according to their ability to self-renew and differentiate into tissues of mesodermal origin. Due to their immuno-modulatory properties and ability to form cartilage and bone, MSCs have clinical potential, for the treatment of autoimmune diseases and tissue ...
openaire   +4 more sources

Wharton’s jelly or bone marrow mesenchymal stromal cells improve cardiac function following myocardial infarction for more than 32 weeks in a rat model: a preliminary report [PDF]

, 2013
The therapeutic effect of mesenchymal stromal cells (MSCs) following myocardial infarction (MI) is small. This may be due to differences in cellular sources and donor age, route of administration, in vitro cellular manipulations and the short time course
Borgarelli, Michele, Hageman, Karen S., Lutjemeier, Barbara, López, Yelica, Musch, Timothy I., Seshareddy, Kiran, Trevino, Elizabeth M., Weiss, Mark L.   +7 more
core   +2 more sources

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Immunosuppressive and remodelling properties of mesenchymal stem cells in a model of chronic kidney disease [PDF]

Einstein (São Paulo), 2009
Objective: To investigate the role of mesenchymal stem cells in fibrogenesis using a model of chronic renal insufficiency. Methods: Mesenchymal stem cells  were obtained from tibias and femurs of Wistar-EPM rats.
Patricia Semedo, Matheus Corrêa-Costa, Marcos Antonio Cenedeze, Denise Maria Avancini Costa Malheiros, Maria Heloisa Massola Shimizu, Antonio Carlos Seguro, Alvaro Pacheco-Silva, Niels Olsen Saraiva Câmara   +7 more
doaj  

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

Nature Communications, 2015
Mesenchymal stem cells (MSCs) and macrophages are fundamental components of the stem cell niche and function coordinately to regulate haematopoietic stem cell self-renewal and mobilization. Recent studies indicate that mitophagy and healthy mitochondrial
D. Phinney, Michelangelo Di Giuseppe, Joel Njah, E. Sala, S. Shiva, C. S. St Croix, D. Stolz, Simon C Watkins, Y. Di, G. Leikauf, J. Kolls, D. Riches, G. DeIuliis, N. Kaminski, Siddaraju V Boregowda, D. McKenna, L. Ortiz   +16 more
semanticscholar   +1 more source