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Mesenchymal stem cells in osteoarthritis
Current Opinion in Rheumatology, 2004Accumulating evidence indicates that every tissue contains stem cells. Our understanding of the biology of stem cells reveals that these cell populations have a critical role in the homeostasis and repair of tissues. Besides the local stem cell niches, additional compartments in the body such as the bone marrow may serve as reservoirs for stem cell ...
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Mesenchymal Stem/Stromal Cells: MESENCHYMAL STEM/STROMAL CELLS
Cytotherapy, 2023E. Heyman +3 more
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Mesenchymal stem cells and haematopoietic stem cell transplantation
Best Practice & Research Clinical Haematology, 2004The bone marrow serves as a reservoir for different classes of stem cells. In addition to haemopoietic stem cells, the bone marrow comprises a population of marrow stromal cells or mesenchymal stem cells (MSCs). These cells exhibit multilineage differentiation capacity, and are able to generate progenitors with restricted developmental potential ...
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Mesenchymal Stem Cells and Haematopoietic Stem Cell Culture
2012Haematopoietic stem cell (HSC) transplantation is an established cell-based therapy for a number of haematological malignancies and immunodeficiency diseases. However, the limited number of HSC from umbilical cord blood (UCB) limits the efficacy of transplants from this source.
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The multifaceted role of mesenchymal stem cells in cancer
Seminars in Cancer Biology, 2020Yuval Shaked +2 more
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2017
Induced Pluripotent Stem Cells (iPSCs) are adult somatic cells genetically reprogrammed to an embryonic stem cell-like state. Fibroblast (FB) is the adult somatic cell most commonly used for reprogramming and is defined by spindle-shape morphology, plastic-adherence and expression of several markers. Nonetheless, such properties also define Mesenchymal
Sacco A +11 more
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Induced Pluripotent Stem Cells (iPSCs) are adult somatic cells genetically reprogrammed to an embryonic stem cell-like state. Fibroblast (FB) is the adult somatic cell most commonly used for reprogramming and is defined by spindle-shape morphology, plastic-adherence and expression of several markers. Nonetheless, such properties also define Mesenchymal
Sacco A +11 more
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The elusive nature and function of mesenchymal stem cells
Nature Reviews Molecular Cell Biology, 2011Jérôme Ritz +2 more
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Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets
Nature Reviews Drug Discovery, 2016Yufang Shi, Liming Du, Ying Wang
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