Results 81 to 90 of about 1,363,551 (403)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

The Effect of Adipose-Derived Stem Cell Supernatant on Reducing Sperm Damage During Freezing and Thawing

open access: yesArmaghane Danesh Bimonthly Journal, 2020
Background & aim: Infertility and its individual and social problems are one of the main and important issues and concerns of couples and about half of all infertility is related to men.
F Saghaiti   +3 more
doaj  

Differentiated Stem Cells Derived from Rabbit Adipose Tissue Exhibited in ‎Vitro Adipogenesis and Osteogenesis

open access: yesThe Iraqi Journal of Veterinary Medicine, 2023
The multipotent characteristic of rabbit adipose-derived stem cells makes them available and ‎convenient sources for isolating mesenchymal stem cells.
Dhurgham H Al-Haideri   +1 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Mesenchymal stem/stromal cells in cancer therapy

open access: yesJournal of Hematology & Oncology, 2021
The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone marrow in 1976, have been identified in nearly all tissues of human body now. The multipotency of MSCs allows them to give rise to osteocytes, chondrocytes, adipocytes,
Tianxia Lan, Min Luo, Xiawei Wei
semanticscholar   +1 more source

Mesenchymal Stem Cells in Cardiology [PDF]

open access: yes, 2016
Cardiovascular disease (CVD) accounts for more deaths globally than any other single disease. There are on average 1.5 million episodes of myocardial infarction (heart attack) each year in the United States alone with roughly one-third resulting in death.
Cristina Sanina   +3 more
openaire   +3 more sources

Mesenchymal stem cells for management of rheumatoid arthritis : immune modulation, repair or both? [PDF]

open access: yes, 2018
The authors are grateful for support to their research from Arthritis Research UK (grants 19271, 19429, 19667, 20050, 20775) and the Medical Research Council (grant no.
Ansboro, Sharon   +2 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Human mesenchymal stem cells - current trends and future prospective

open access: yesBioscience Reports, 2015
Stem cells are cells specialized cell, capable of renewing themselves through cell division and can differentiate into multi-lineage cells. These cells are categorized as embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs) and adult stem ...
Imran Ullah, R. Subbarao, G. Rho
semanticscholar   +1 more source

Homing of Mesenchymal Stem Cells [PDF]

open access: yesTransfusion Medicine and Hemotherapy, 2008
SUMMARY: Mesenchymal stem cells (MSCs) are primarily fibroblast-like cells. Yet, once studied under conditions of shear stress when flowing along endothelial cells in vitro or in blood vessels, as well as in classic migration assays such as chemotaxis assays, MSCs have recently been found to function similarly to leukocytes in many ways.
Reinhard Henschler   +2 more
openaire   +3 more sources

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